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# CITATION file created with {cffr} R package
# See also: https://docs.ropensci.org/cffr/
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cff-version: 1.2.0
message: 'To cite package "garfield" in publications use:'
type: software
license: GPL-3.0-only
title: 'garfield: GWAS Analysis of Regulatory or Functional Information Enrichment
  with LD correction'
version: 1.33.0
abstract: 'GARFIELD is a non-parametric functional enrichment analysis approach described
  in the paper GARFIELD: GWAS analysis of regulatory or functional information enrichment
  with LD correction. Briefly, it is a method that leverages GWAS findings with regulatory
  or functional annotations (primarily from ENCODE and Roadmap epigenomics data) to
  find features relevant to a phenotype of interest. It performs greedy pruning of
  GWAS SNPs (LD r2 > 0.1) and then annotates them based on functional information
  overlap. Next, it quantifies Fold Enrichment (FE) at various GWAS significance cutoffs
  and assesses them by permutation testing, while matching for minor allele frequency,
  distance to nearest transcription start site and number of LD proxies (r2 > 0.8).'
authors:
- family-names: Iotchkova
  given-names: Valentina
  email: vi1@sanger.ac.uk
- family-names: Morganella
  given-names: Sandro
  email: sm22@sanger.ac.uk
repository: https://bioc.r-universe.dev
date-released: '2015-12-14'
contact:
- family-names: Iotchkova
  given-names: Valentina
  email: vi1@sanger.ac.uk