Package: edgeR Version: 4.99.11 Date: 2026-10-31 Title: Empirical Analysis of Digital Gene Expression Data in R Description: Differential expression analysis of sequence count data. Implements a range of statistical methodology based on the negative binomial distributions, including empirical Bayes estimation, exact tests, generalized linear models, quasi-likelihood, and gene set enrichment. Can perform differential analyses of any type of omics data that produces read counts, including RNA-seq, ChIP-seq, ATAC-seq, Bisulfite-seq, SAGE, CAGE, metabolomics, or proteomics spectral counts. RNA-seq analyses can be conducted at the gene or isoform level, and tests can be conducted for differential exon or transcript usage. Author: Yunshun Chen, Lizhong Chen, Aaron TL Lun, Davis J McCarthy, Pedro Baldoni, Matthew E Ritchie, Belinda Phipson, Yifang Hu, Xiaobei Zhou, Mark D Robinson, Gordon K Smyth Maintainer: Yunshun Chen , Gordon Smyth License: GPL (>=2) Depends: R (>= 3.6.0), limma (>= 3.63.6) Imports: methods, graphics, stats, utils Suggests: jsonlite, knitr, Matrix, nanoparquet, readr, rhdf5, SeuratObject, splines, AnnotationDbi, Biobase, BiocStyle, org.Hs.eg.db, S4Vectors, SummarizedExperiment VignetteBuilder: knitr URL: https://bioinf.wehi.edu.au/edgeR/, https://bioconductor.org/packages/edgeR biocViews: AlternativeSplicing, BatchEffect, Bayesian, BiomedicalInformatics, CellBiology, ChIPSeq, Clustering, Coverage, DifferentialExpression, DifferentialMethylation, DifferentialSplicing, DNAMethylation, Epigenetics, FunctionalGenomics, GeneExpression, GeneSetEnrichment, Genetics, Genetics, ImmunoOncology, MultipleComparison, Normalization, Pathways, Proteomics, QualityControl, Regression, RNASeq, SAGE, Sequencing, SingleCell, SystemsBiology, TimeCourse, Transcription, Transcriptomics NeedsCompilation: yes Repository: https://bioc.r-universe.dev Date/Publication: 2026-10-31 21:11:33 UTC RemoteUrl: https://github.com/bioc/edgeR RemoteRef: HEAD RemoteSha: c708c74473eb7781078133cb51a4f0ffa77f3b67 Packaged: 2026-10-31 22:26:08 UTC; root