Package: drugTargetInteractions
Type: Package
Title: drugTargetInteractions: Mining the Druggable Genome
Version: 1.21.15
Date: 2026-10-13
Authors@R: c(
    person("Thomas", "Girke", email="thomas.girke@ucr.edu", role=c("cre", "aut"), comment=c(ORCID="0000-0003-0710-3777")),
    person("Kevin", "Horan", role="ctb"))
Description: Utilities for identifying known drug-target interactions
        for sets of query drug and/or target protein (gene)
        identifiers. The interaction information is obtained from a
        series of drug and target databases, including ChEMBL, PubChem,
        DGIdb, Open Targets, the Therapeutic Target Database, the Broad
        Institute Drug Repurposing Hub and the IUPHAR/BPS Guide to
        PHARMACOLOGY. Each source can be queried on its own, or several
        of them combined into a single table anchored on HGNC gene
        identifiers. Identifier translation utilities map query
        identifiers onto the native identifier types each source
        expects.
Depends: methods, R (>= 4.1)
Imports: utils, stats, RSQLite, UniProt.ws, biomaRt,ensembldb,
        BiocFileCache,rappdirs, AnnotationFilter, S4Vectors, httr2,
        readxl, jsonlite
Suggests: RUnit, BiocStyle, knitr, rmarkdown, ggplot2, reshape2, DT,
        EnsDb.Hsapiens.v86, testthat (>= 3.0.0)
VignetteBuilder: knitr
License: Artistic-2.0
Encoding: UTF-8
NeedsCompilation: no
URL: https://github.com/girke-lab/drugTargetInteractions
biocViews: Cheminformatics, BiomedicalInformatics, Pharmacogenetics,
        Pharmacogenomics, Proteomics, Metabolomics, GeneTarget, Network
Config/testthat/edition: 3
BugReports: https://github.com/girke-lab/drugTargetInteractions
Config/roxygen2/version: 8.0.0
Config/pak/sysreqs: make libbz2-dev libicu-dev liblzma-dev libpng-dev
        libxml2-dev libssl-dev xz-utils zlib1g-dev
Repository: https://bioc.r-universe.dev
Date/Publication: 2026-10-17 02:36:23 UTC
RemoteUrl: https://github.com/bioc/drugTargetInteractions
RemoteRef: HEAD
RemoteSha: bf6616552e125642ac04d795dec153c00ca63000
Packaged: 2026-10-17 11:03:48 UTC; root
Author: Thomas Girke [cre, aut] (ORCID:
    <https://orcid.org/0000-0003-0710-3777>),
  Kevin Horan [ctb]
Maintainer: Thomas Girke <thomas.girke@ucr.edu>