Package: dorothea
Type: Package
Title: Collection Of Human And Mouse TF Regulons
Version: 1.25.0
Authors@R: c(
    person(given = "Pau",
           family = "Badia-i-Mompel",
           role = c("cre"),
           email = "pau.badia@uni-heidelberg.de",
           comment = c(ORCID = "0000-0002-1004-3923")),
    person(given = "Daniel",
           family = "Dimitrov",
           role = c("aut"),
           email = "daniel.dimitrov@uni-heidelberg.de",
           comment = c(ORCID = "0000-0002-5197-2112")),
    person(given = "Christian H.",
           family = "Holland",
           role = c("aut"),
           email = "cholland2408@gmail.com",
           comment = c(ORCID = "0000-0002-3060-5786")),
    person(given = "Luz",
           family = "Garcia-Alonso",
           role = "aut"),
    person(given = "Alberto",
           family = "Valdeolivas",
           role = "ctb"),
    person(given = "Minoo",
           family = "Ashtiani",
           role = "ctb"),
    person(given = "Attila",
           family = "Gabor",
           role = "ctb")
           )
Description: DoRothEA is a gene regulatory network containing signed
        transcription factor (TF) - target gene interactions. DoRothEA
        regulons, the collection of a TF and its transcriptional
        targets, were curated and collected from different types of
        evidence for both human and mouse. A confidence level was
        assigned to each TF-target interaction based on the number of
        supporting evidence.
URL: https://saezlab.github.io/dorothea/,
        https://github.com/saezlab/dorothea
BugReports: https://github.com/saezlab/dorothea/issues
Depends: R (>= 4.0)
License: GPL-3 + file LICENSE
Encoding: UTF-8
LazyData: true
LazyDataCompression: xz
RoxygenNote: 7.2.3
VignetteBuilder: knitr
biocViews: ExperimentData, Homo_sapiens_Data, Mus_musculus_Data
Imports: dplyr, magrittr, bcellViper, decoupleR,
Suggests: Biobase, BiocStyle, OmnipathR, viper, knitr, pheatmap,
        pkgdown, rmarkdown, Seurat, SingleCellExperiment,
        SummarizedExperiment, testthat (>= 2.1.0), tibble, tidyr, utils
Config/pak/sysreqs: libicu-dev
Repository: https://bioc.r-universe.dev
Date/Publication: 2026-04-28 12:34:00 UTC
RemoteUrl: https://github.com/bioc/dorothea
RemoteRef: HEAD
RemoteSha: 4feba311dcfeaea16ba2302675d7227a322b214b
NeedsCompilation: no
Packaged: 2026-10-10 10:43:20 UTC; root
Author: Pau Badia-i-Mompel [cre] (ORCID:
    <https://orcid.org/0000-0002-1004-3923>),
  Daniel Dimitrov [aut] (ORCID: <https://orcid.org/0000-0002-5197-2112>),
  Christian H. Holland [aut] (ORCID:
    <https://orcid.org/0000-0002-3060-5786>),
  Luz Garcia-Alonso [aut],
  Alberto Valdeolivas [ctb],
  Minoo Ashtiani [ctb],
  Attila Gabor [ctb]
Maintainer: Pau Badia-i-Mompel <pau.badia@uni-heidelberg.de>