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# CITATION file created with {cffr} R package
# See also: https://docs.ropensci.org/cffr/
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cff-version: 1.2.0
message: 'To cite package "dmrseq" in publications use:'
type: software
license: MIT
title: 'dmrseq: Detection and inference of differentially methylated regions from
  Whole Genome Bisulfite Sequencing'
version: 1.25.0
doi: 10.1093/biostatistics/kxy007
abstract: This package implements an approach for scanning the genome to detect and
  perform accurate inference on differentially methylated regions from Whole Genome
  Bisulfite Sequencing data. The method is based on comparing detected regions to
  a pooled null distribution, that can be implemented even when as few as two samples
  per population are available. Region-level statistics are obtained by fitting a
  generalized least squares (GLS) regression model with a nested autoregressive correlated
  error structure for the effect of interest on transformed methylation proportions.
authors:
- family-names: Korthauer
  given-names: Keegan
  email: keegan@stat.ubc.ca
  orcid: https://orcid.org/0000-0002-4565-1654
- family-names: Irizarry
  given-names: Rafael
  email: rafa@jimmy.harvard.edu
  orcid: https://orcid.org/0000-0002-3944-4309
- family-names: Benjamini
  given-names: Yuval
- family-names: Chakraborty
  given-names: Sutirtha
preferred-citation:
  type: article
  title: Detection and accurate false discovery rate control of differentially methylated
    regions from whole genome bisulfite sequencing
  authors:
  - family-names: Korthauer
    given-names: Keegan
    email: keegan@stat.ubc.ca
    orcid: https://orcid.org/0000-0002-4565-1654
  - family-names: Chakraborty
    given-names: Sutirtha
  - family-names: Benjamini
    given-names: Yuval
  - family-names: Irizarry
    given-names: Rafael A
  journal: Biostatistics
  year: '2018'
  doi: 10.1093/biostatistics/kxy007
  start: kxy007
repository: https://bioc.r-universe.dev
contact:
- family-names: Korthauer
  given-names: Keegan
  email: keegan@stat.ubc.ca
  orcid: https://orcid.org/0000-0002-4565-1654