dmGsea

Efficient Gene Set Enrichment Analysis for DNA Methylation Data

Introduction

The R package dmGsea is specifically designed for DNA methylation data, provides functions to perform gene set enrichment analysis while addressing probe dependency and probe number bias. The package supports Illumina 450K, EPIC, and mouse methylation arrays and can be extended to other omics data with user-provided probe-to-gene mapping annotations.

Installation

From Bioconductor (recommended)

You can install the stable version of dmGsea from Bioconductor using the following command:

if (!requireNamespace("BiocManager", quietly = TRUE))
    install.packages("BiocManager")
BiocManager::install("dmGsea")