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# CITATION file created with {cffr} R package
# See also: https://docs.ropensci.org/cffr/
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cff-version: 1.2.0
message: 'To cite package "distinct" in publications use:'
type: software
license: GPL-3.0-or-later
title: 'distinct: distinct: a method for differential analyses via hierarchical permutation
  tests'
version: 1.17.0
doi: 10.1214/22-AOAS1689
abstract: 'distinct is a statistical method to perform differential testing between
  two or more groups of distributions; differential testing is performed via hierarchical
  non-parametric permutation tests on the cumulative distribution functions (cdfs)
  of each sample. While most methods for differential expression target differences
  in the mean abundance between conditions, distinct, by comparing full cdfs, identifies,
  both, differential patterns involving changes in the mean, as well as more subtle
  variations that do not involve the mean (e.g., unimodal vs. bi-modal distributions
  with the same mean). distinct is a general and flexible tool: due to its fully non-parametric
  nature, which makes no assumptions on how the data was generated, it can be applied
  to a variety of datasets. It is particularly suitable to perform differential state
  analyses on single cell data (i.e., differential analyses within sub-populations
  of cells), such as single cell RNA sequencing (scRNA-seq) and high-dimensional flow
  or mass cytometry (HDCyto) data. To use distinct one needs data from two or more
  groups of samples (i.e., experimental conditions), with at least 2 samples (i.e.,
  biological replicates) per group.'
authors:
- family-names: Tiberi
  given-names: Simone
  email: simone.tiberi@uzh.ch
- family-names: Tiberi.
  given-names: Simone
preferred-citation:
  type: article
  title: 'distinct: a novel approach to differential distribution analyses'
  authors:
  - family-names: Tiberi
    given-names: Simone
    email: simone.tiberi@uzh.ch
  - family-names: Crowell
    given-names: Helana L
  - family-names: Samartsidis
    given-names: Pantelis
  - family-names: Weber
    given-names: Lukas M
  - family-names: Robinson
    given-names: Mark D.
  journal: The Annals of Applied Statistics
  volume: '17'
  issue: '2'
  year: '2023'
  doi: 10.1214/22-AOAS1689
  url: https://doi.org/10.1214/22-AOAS1689
  publisher:
    name: Institute of Mathematical Statistics
repository: https://bioc.r-universe.dev
repository-code: https://github.com/SimoneTiberi/distinct
url: https://github.com/SimoneTiberi/distinct
contact:
- family-names: Tiberi
  given-names: Simone
  email: simone.tiberi@uzh.ch