# -------------------------------------------- # CITATION file created with {cffr} R package # See also: https://docs.ropensci.org/cffr/ # -------------------------------------------- cff-version: 1.2.0 message: 'To cite package "dinoR" in publications use:' type: software license: MIT title: 'dinoR: Differential NOMe-seq analysis' version: 1.3.0 doi: 10.32614/CRAN.package.dinoR abstract: dinoR tests for significant differences in NOMe-seq footprints between two conditions, using genomic regions of interest (ROI) centered around a landmark, for example a transcription factor (TF) motif. This package takes NOMe-seq data (GCH methylation/protection) in the form of a Ranged Summarized Experiment as input. dinoR can be used to group sequencing fragments into 3 or 5 categories representing characteristic footprints (TF bound, nculeosome bound, open chromatin), plot the percentage of fragments in each category in a heatmap, or averaged across different ROI groups, for example, containing a common TF motif. It is designed to compare footprints between two sample groups, using edgeR's quasi-likelihood methods on the total fragment counts per ROI, sample, and footprint category. authors: - family-names: Schwaiger given-names: Michaela email: michaela.schwaiger@fmi.ch orcid: https://orcid.org/0000-0002-4522-7810 repository: https://bioc.r-universe.dev repository-code: https://github.com/xxxmichixxx/dinoR commit: eaf277e1358a4096fd0e809e765675155cd329f4 url: https://github.com/xxxmichixxx/dinoR contact: - family-names: Schwaiger given-names: Michaela email: michaela.schwaiger@fmi.ch orcid: https://orcid.org/0000-0002-4522-7810