Package: diffHic Version: 1.45.3 Date: 2026-10-12 Title: Differential Analysis of Hi-C Data Author: Aaron Lun, Gordon Smyth Maintainer: Gordon Smyth , Aaron Lun , Hannah Coughlin Depends: R (>= 3.5), GenomicRanges, InteractionSet, SummarizedExperiment Imports: Rsamtools, Rhtslib, Biostrings, BSgenome, rhdf5, edgeR, limma, csaw, locfit, methods, IRanges, S4Vectors, GenomeInfoDb, BiocGenerics, grDevices, graphics, stats, utils, Rcpp, rtracklayer Suggests: BSgenome.Ecoli.NCBI.20080805, Matrix, testthat biocViews: MultipleComparison, Preprocessing, Sequencing, Coverage, Alignment, Normalization, Clustering, HiC Description: Detects differential interactions across biological conditions in a Hi-C experiment. Methods are provided for read alignment and data pre-processing into interaction counts. Statistical analysis is based on edgeR and supports normalization and filtering. Several visualization options are also available. License: GPL (>=2) NeedsCompilation: yes LinkingTo: Rhtslib (>= 1.13.1), Rcpp SystemRequirements: GNU make Config/pak/sysreqs: make libbz2-dev liblzma-dev libxml2-dev libssl-dev xz-utils zlib1g-dev Repository: https://bioc.r-universe.dev Date/Publication: 2026-10-12 07:23:43 UTC RemoteUrl: https://github.com/bioc/diffHic RemoteRef: HEAD RemoteSha: cd5dd6e2ab1731f1352c4e9dd6419eae1ca781fb Packaged: 2026-10-13 03:50:37 UTC; root