Package: depmap
Type: Package
Title: Cancer Dependency Map Data Package
Version: 1.27.0
Authors@R: c(person(given = "Laurent", family = "Gatto",
                    email = "laurent.gatto@uclouvain.be",
                    comment = c(ORCID = "0000-0002-1520-2268"),
                    role = c("cre", "aut")),
            person(given = "Theo", family = "Killian",
                    role = "aut"),
            person(given = "Alexander", family = "Peltzer", role = "ctb",
                    comment = c(ORCID = "0000-0002-6503-2180")))
Description: The depmap package is a data package that accesses datsets
        from the Broad Institute DepMap cancer dependency study using
        ExperimentHub. Datasets from the most current release are
        available, including RNAI and CRISPR-Cas9 gene knockout screens
        quantifying the genetic dependency for select cancer cell
        lines. Additional datasets are also available pertaining to the
        log copy number of genes for select cell lines, protein
        expression of cell lines as measured by reverse phase protein
        lysate microarray (RPPA), 'Transcript Per Million' (TPM) data,
        as well as supplementary datasets which contain metadata and
        mutation calls for the other datasets found in the current
        release. The 19Q3 release adds the drug_dependency dataset,
        that contains cancer cell line dependency data with respect to
        drug and drug-candidate compounds. The 20Q2 release adds the
        proteomic dataset that contains quantitative profiling of
        proteins via mass spectrometry. This package will be updated on
        a quarterly basis to incorporate the latest Broad Institute
        DepMap Public cancer dependency datasets. All data made
        available in this package was generated by the Broad Institute
        DepMap for research purposes and not intended for clinical use.
        This data is distributed under the Creative Commons license
        (Attribution 4.0 International (CC BY 4.0)).
Depends: R (>= 4.1.0), methods, dplyr
Imports: utils, ExperimentHub, AnnotationHub, BiocFileCache, httr2,
        curl, tibble
License: Artistic-2.0
Encoding: UTF-8
RoxygenNote: 7.3.1
Suggests: knitr, rmarkdown, BiocStyle, viridis, gridExtra, ggplot2,
        readr, stringr, tidyverse, magick
VignetteBuilder: knitr
biocViews: ExperimentHub, ExperimentData, ReproducibleResearch,
        RepositoryData, AssayDomainData, CopyNumberVariationData,
        DiseaseModel, CancerData, BreastCancerData, ColonCancerData,
        KidneyCancerData, LeukemiaCancerData, LungCancerData,
        OvarianCancerData, ProstateCancerData, OrganismData,
        Homo_sapiens_Data, PackageTypeData, SpecimenSource,
        CellCulture, Genome, Proteome, StemCell, Tissue
Config/pak/sysreqs: libicu-dev libpng-dev libssl-dev zlib1g-dev
Repository: https://bioc.r-universe.dev
Date/Publication: 2026-04-28 12:33:14 UTC
RemoteUrl: https://github.com/bioc/depmap
RemoteRef: HEAD
RemoteSha: c9de6f901e091e7458420ec727c443b8975129dc
NeedsCompilation: no
Packaged: 2026-10-10 10:46:54 UTC; root
Author: Laurent Gatto [cre, aut] (ORCID:
    <https://orcid.org/0000-0002-1520-2268>),
  Theo Killian [aut],
  Alexander Peltzer [ctb] (ORCID:
    <https://orcid.org/0000-0002-6503-2180>)
Maintainer: Laurent Gatto <laurent.gatto@uclouvain.be>