Package: deconvR Title: Simulation and Deconvolution of Omic Profiles Version: 1.19.0 Date: 2025-07-28 Authors@R: c(person(given = "Irem B.", family = "Gündüz", role = c("aut", "cre"), email = "irembgunduz@gmail.com", comment = c(ORCID = "0000-0003-2641-0916")), person(given = "Veronika", family = "Ebenal", role = c("aut"), email = "veronikaebenal@gmail.com", comment = c(ORCID = "0000-0001-7976-3964")), person(given = "Altuna", family = "Akalin", role = c("aut"), email = "aakalin@gmail.com", comment = c(ORCID = "0000-0002-0468-0117"))) Description: This package provides a collection of functions designed for analyzing deconvolution of the bulk sample(s) using an atlas of reference omic signature profiles and a user-selected model. Users are given the option to create or extend a reference atlas and,also simulate the desired size of the bulk signature profile of the reference cell types.The package includes the cell-type-specific methylation atlas and, Illumina Epic B5 probe ids that can be used in deconvolution. Additionally,we included BSmeth2Probe, to make mapping WGBS data to their probe IDs easier. License: Artistic-2.0 URL: https://github.com/BIMSBbioinfo/deconvR BugReports: https://support.bioconductor.org/t/deconvR biocViews: DNAMethylation, Regression, GeneExpression, RNASeq, SingleCell, StatisticalMethod, Transcriptomics Encoding: UTF-8 LazyData: false Roxygen: list(markdown = TRUE) RoxygenNote: 7.2.1 Depends: R (>= 4.1), data.table (>= 1.14.0) Imports: S4Vectors (>= 0.30.0), methylKit (>= 1.18.0), IRanges (>= 2.26.0), GenomicRanges (>= 1.44.0), BiocGenerics (>= 0.38.0), stats, methods, foreach (>= 1.5.1), magrittr (>= 2.0.1), matrixStats (>= 0.61.0), e1071 (>= 1.7.9), quadprog (>= 1.5.8), nnls (>= 1.4), rsq (>= 2.2), MASS, utils, dplyr (>= 1.0.7), tidyr (>= 1.1.3), assertthat, minfi Suggests: testthat (>= 3.0.0), roxygen2 (>= 7.1.2), doParallel (>= 1.0.16), parallel, knitr (>= 1.34), BiocStyle (>= 2.20.2), reshape2 (>= 1.4.4), ggplot2 (>= 3.3.5), rmarkdown, devtools (>= 2.4.2), sessioninfo (>= 1.1.1), covr, granulator, RefManageR VignetteBuilder: knitr Config/testthat/edition: 3 Config/pak/sysreqs: cmake make libbz2-dev libicu-dev liblzma-dev libpng-dev libxml2-dev libssl-dev libx11-dev xz-utils zlib1g-dev Repository: https://bioc.r-universe.dev Date/Publication: 2026-04-28 12:57:19 UTC RemoteUrl: https://github.com/bioc/deconvR RemoteRef: HEAD RemoteSha: 2779e925bba5bb7b17edf5cc4c1f2038ab176518 NeedsCompilation: no Packaged: 2026-07-04 04:25:43 UTC; root Author: Irem B. Gündüz [aut, cre] (ORCID: ), Veronika Ebenal [aut] (ORCID: ), Altuna Akalin [aut] (ORCID: ) Maintainer: Irem B. Gündüz