Package: debrowser Type: Package Title: Interactive Differential Expresion Analysis Browser Version: 1.41.2 Date: 2026-07-23 Authors@R: c( person("Alper", "Kucukural", email = "alper.kucukural@umassmed.edu", role = c("aut", "cre")), person("Onur", "Yukselen", email = "onur.yukselen@umassmed.edu", role = "aut"), person("Manuel", "Garber", email = "manuel.garber@umassmed.edu", role = "aut")) Description: Bioinformatics platform containing interactive plots and tables for differential gene and region expression studies. Allows visualizing expression data much more deeply in an interactive and faster way. By changing the parameters, users can easily discover different parts of the data that like never have been done before. Manually creating and looking these plots takes time. With DEBrowser users can prepare plots without writing any code. Differential expression, PCA and clustering analysis are made on site and the results are shown in various plots such as scatter, bar, box, volcano, ma plots and Heatmaps. Depends: R (>= 4.2.0), License: GPL-3 + file LICENSE Imports: shiny, jsonlite, shinyjs, shinyBS, shinyWidgets, gplots, DT, ggplot2, annotate, AnnotationDbi, DESeq2, igraph, grDevices, graphics, stats, utils, GenomicRanges, IRanges, S4Vectors, SummarizedExperiment, stringi, reshape2, org.Hs.eg.db, limma, edgeR, clusterProfiler, methods, sva, RCurl, colourpicker, plotly, heatmaply, bslib (>= 0.7.0), htmltools RoxygenNote: 8.0.0 Encoding: UTF-8 Suggests: testthat (>= 3.2.0), rmarkdown, RSQLite, knitr, digest, shinymanager (>= 1.0.4), shinytest2, chromote, DBI, Harman, pathview, org.Mm.eg.db, apeglm, ashr, commonmark, enrichplot, fgsea, ipaddress (>= 1.0), mockery, msigdbr, openssl, scrypt, UpSetR, DOSE, ellmer (>= 0.1.0), keyring, whisker, withr, xml2 Config/testthat/edition: 3 VignetteBuilder: knitr URL: https://github.com/UMMS-Biocore/debrowser, https://debrowser.readthedocs.io BugReports: https://github.com/UMMS-Biocore/debrowser/issues/new biocViews: Sequencing, ChIPSeq, RNASeq, DifferentialExpression, GeneExpression, Clustering, ImmunoOncology Config/pak/sysreqs: libcairo2-dev cmake libfontconfig1-dev libfreetype6-dev libglpk-dev make libmagick++-dev gsfonts libicu-dev libpng-dev libuv1-dev libxml2-dev libssl-dev zlib1g-dev Repository: https://bioc.r-universe.dev Date/Publication: 2026-07-23 18:20:13 UTC RemoteUrl: https://github.com/bioc/debrowser RemoteRef: HEAD RemoteSha: f1190cd970fa9d26b27f8300a0a0a21d83bdf682 NeedsCompilation: no Packaged: 2026-07-25 09:26:24 UTC; root Author: Alper Kucukural [aut, cre], Onur Yukselen [aut], Manuel Garber [aut] Maintainer: Alper Kucukural