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# CITATION file created with {cffr} R package
# See also: https://docs.ropensci.org/cffr/
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cff-version: 1.2.0
message: 'To cite package "dce" in publications use:'
type: software
license: GPL-3.0-only
title: 'dce: Pathway Enrichment Based on Differential Causal Effects'
version: 1.13.0
doi: 10.1093/bioinformatics/btab847
abstract: Compute differential causal effects (dce) on (biological) networks. Given
  observational samples from a control experiment and non-control (e.g., cancer) for
  two genes A and B, we can compute differential causal effects with a (generalized)
  linear regression. If the causal effect of gene A on gene B in the control samples
  is different from the causal effect in the non-control samples the dce will differ
  from zero. We regularize the dce computation by the inclusion of prior network information
  from pathway databases such as KEGG.
authors:
- family-names: Jablonski
  given-names: Kim Philipp
  email: kim.philipp.jablonski@gmail.com
  orcid: https://orcid.org/0000-0002-4166-4343
- family-names: Pirkl
  given-names: Martin
  email: martinpirkl@yahoo.de
preferred-citation:
  type: article
  title: Identifying cancer pathway dysregulations using differential causal effects
  authors:
  - name: Jablonski
  - family-names: Philipp
    given-names: Kim
  - name: Pirkl
  - name: Martin
  - name: '''Cevid'
  - name: Domagoj
  - name: B"uhlmann
  - name: Peter
  - name: Beerenwinkel
  - name: Niko
  journal: Bioinformatics
  year: '2021'
  doi: 10.1093/bioinformatics/btab847
  url: https://doi.org/10.1093/bioinformatics/btab847
repository: https://bioc.r-universe.dev
repository-code: https://github.com/cbg-ethz/dce
url: https://github.com/cbg-ethz/dce
contact:
- family-names: Jablonski
  given-names: Kim Philipp
  email: kim.philipp.jablonski@gmail.com
  orcid: https://orcid.org/0000-0002-4166-4343