Package: cypress Type: Package Title: Cell-Type-Specific Power Assessment Version: 1.9.0 Date: 2024-05-27 Authors@R: c( person("Shilin", "Yu", role=c("aut", "cre"),email= "sy597@georgetown.edu",comment=c(ORCID="0000-0002-5494-1960")), person("Guanqun", "Meng", role="aut",email="gxm324@case.edu"), person("Wen", "Tang", role="aut",email="wxt175@case.edu")) License: GPL-2 | GPL-3 Depends: R(>= 4.4.0) Imports: stats, abind, sirt, MASS,TOAST, tibble, parallel, preprocessCore, SummarizedExperiment, TCA, PROPER, methods,dplyr, utils, RColorBrewer, graphics, edgeR, BiocParallel, checkmate, mvtnorm, DESeq2, rlang, e1071 Suggests: knitr, rmarkdown, MatrixGenerics, htmltools, RUnit, BiocGenerics, BiocManager, BiocStyle, Biobase Collate: AllClasses.R AllGenerics.R CIBERSORT.R csRNA_seq_sim.R cypress_design.R cypress_wrapper.R cypressEmbedded.R metrics.R cypress-methods.R PlotTDR.R DE_arg.R TOAST_implement.R user.R util_datasim.R util_EST.R PlotFDC.R PlotPower.R biocViews: Software, GeneExpression, DataImport, RNASeq, Sequencing Description: CYPRESS is a cell-type-specific power tool. This package aims to perform power analysis for the cell-type-specific data. It calculates FDR, FDC, and power, under various study design parameters, including but not limited to sample size, and effect size. It takes the input of a SummarizeExperimental(SE) object with observed mixture data (feature by sample matrix), and the cell-type mixture proportions (sample by cell-type matrix). It can solve the cell-type mixture proportions from the reference free panel from TOAST and conduct tests to identify cell-type-specific differential expression (csDE) genes. Encoding: UTF-8 LazyData: FALSE VignetteBuilder: knitr URL: https://github.com/renlyly/cypress BugReports: https://github.com/renlyly/cypress/issues Config/pak/sysreqs: cmake libicu-dev libpng-dev libxml2-dev libssl-dev zlib1g-dev Repository: https://bioc.r-universe.dev Date/Publication: 2026-04-28 13:02:45 UTC RemoteUrl: https://github.com/bioc/cypress RemoteRef: HEAD RemoteSha: b8b699f3d2305dc664a8a614155f581f6d74d876 NeedsCompilation: no Packaged: 2026-07-04 09:46:10 UTC; root Author: Shilin Yu [aut, cre] (ORCID: ), Guanqun Meng [aut], Wen Tang [aut] Maintainer: Shilin Yu