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# CITATION file created with {cffr} R package
# See also: https://docs.ropensci.org/cffr/
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cff-version: 1.2.0
message: 'To cite package "crisprScore" in publications use:'
type: software
license: MIT
title: 'crisprScore: On-Target and Off-Target Scoring Algorithms for CRISPR gRNAs'
version: 1.9.0
abstract: 'Provides R wrappers of several on-target and off-target scoring methods
  for CRISPR guide RNAs (gRNAs). The following nucleases are supported: SpCas9, AsCas12a,
  enAsCas12a, and RfxCas13d (CasRx). The available on-target cutting efficiency scoring
  methods are RuleSet1, Azimuth, DeepHF, DeepCpf1, enPAM+GB, and CRISPRscan. Both
  the CFD and MIT scoring methods are available for off-target specificity prediction.
  The package also provides a Lindel-derived score to predict the probability of a
  gRNA to produce indels inducing a frameshift for the Cas9 nuclease. Note that DeepHF,
  DeepCpf1 and enPAM+GB are not available on Windows machines.'
authors:
- family-names: Fortin
  given-names: Jean-Philippe
  email: fortin946@gmail.com
- family-names: Lun
  given-names: Aaron
  email: infinite.monkeys.with.keyboards@gmail.com
preferred-citation:
  type: article
  title: A comprehensive Bioconductor ecosystem for the design of CRISPR guide RNAs
    across nucleases and technologies
  authors:
  - family-names: Hoberecht
    given-names: Luke
  - family-names: Perampalam
    given-names: Pirunthan
  - family-names: Lun
    given-names: Aaron
    email: infinite.monkeys.with.keyboards@gmail.com
  - family-names: Fortin
    given-names: Jean-Philippe
    email: fortin946@gmail.com
  journal: Nature Communications
  volume: '13'
  issue: '1'
  year: '2022'
  start: '6568'
repository: https://bioc.r-universe.dev
repository-code: https://github.com/crisprVerse/crisprScore
url: https://github.com/crisprVerse/crisprScore/issues
date-released: '2024-01-16'
contact:
- family-names: Fortin
  given-names: Jean-Philippe
  email: fortin946@gmail.com