NEWS

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crisprDesign 1.7.1

• Fixed getTssObjectFromTxObject for negative strand.

crisprDesign 1.5.2

• Added function addReinitiationFlag.

crisprDesign 1.1.25

• Added a warning message when having duplicated gRNAs.

crisprDesign 1.1.21

• Fixed intergenic annotation of alignments when non-standard chromosomes are found.

crisprDesign 1.1.20

• flattenGuideSet is now GuideSet2DataFrames.

crisprDesign 1.1.19

• Changed argument standard_chr_only to FALSE by default in the functions getSpacerAlignments and friends.

crisprDesign 1.1.18

• Updated the object guideSetExampleWithAlignments to contain the latest annotations.

crisprDesign 1.1.17

• Updated the object guideSetExampleFullAnnotation to contain the latest annotations.

crisprDesign 1.1.12

• Refactored addGeneAnnotation.

crisprDesign 1.1.10

• Added the function getPreMrnaSequence.

crisprDesign 1.1.8

• Added features for non-targeting controls (addNtcs).

crisprDesign 1.0.0

• New package crisprDesign, for the design of CRISPR gRNA.