NEWS

---

cosmosR 1.21.2

• Remove the legacy DoRothEA installation dependency. Classic CARNIVAL preprocessing now requires an explicit TF regulon; use a prepared CollecTRI regulon for new work.
• Retire load_tf_regulon_dorothea() with a clear migration error.

cosmosR 1.21.1

• Declare Pandoc (>= 2.8) as a system requirement for rendering vignettes.

cosmosR 0.99.2

---

• Submitted to bioRxiv
• Release of github page
• Submitted to Bioconductor