Package: concordexR Title: Identify Spatial Homogeneous Regions with concordex Version: 1.13.0 Authors@R: c( person("Kayla", "Jackson", , "kaylajac@caltech.edu", role = c("aut", "cre"), comment = c(ORCID = "0000-0001-6483-0108")), person("A. Sina", "Booeshaghi", , "alisina@caltech.edu", role = "aut", comment = c(ORCID = "0000-0002-6442-4502")), person("Angel", "Galvez-Merchan", , "agalvezm@caltech.edu", role = "aut", comment = c(ORCID = "0000-0001-7420-8697")), person("Lambda", "Moses", , "dlu2@caltech.edu", role = "aut", comment = c(ORCID = "0000-0002-7092-9427")), person("Alexandra", "Kim", , "alexandrasuriya@gmail.com", role = "ctb"), person("Laura", "Luebbert", , "lauraluebbert@caltech.edu", role = "ctb", comment = c(ORCID = "0000-0003-1379-2927")), person("Lior", "Pachter", , "lpachter@caltech.edu", role = c("aut", "rev", "ths"), comment = c(ORCID = "0000-0002-9164-6231")) ) Description: Spatial homogeneous regions (SHRs) in tissues are domains that are homogenous with respect to cell type composition. We present a method for identifying SHRs using spatial transcriptomics data, and demonstrate that it is efficient and effective at finding SHRs for a wide variety of tissue types. concordex relies on analysis of k-nearest-neighbor (kNN) graphs. The tool is also useful for analysis of non-spatial transcriptomics data, and can elucidate the extent of concordance between partitions of cells derived from clustering algorithms, and transcriptomic similarity as represented in kNN graphs. License: Artistic-2.0 URL: https://github.com/pachterlab/concordexR, https://pachterlab.github.io/concordexR/ BugReports: https://github.com/pachterlab/concordexR/issues Depends: R (>= 4.5.0) Imports: BiocGenerics, BiocNeighbors, BiocParallel, bluster, cli, DelayedArray, Matrix, methods, purrr, rlang, SingleCellExperiment, sparseMatrixStats, SpatialExperiment, SummarizedExperiment Suggests: BiocManager, BiocStyle, ggplot2, glue, knitr, mbkmeans, patchwork, rmarkdown, scater, SFEData, SpatialFeatureExperiment, TENxPBMCData, testthat (>= 3.0.0) VignetteBuilder: knitr biocViews: SingleCell, Clustering, Spatial, Transcriptomics Config/testthat/edition: 3 Encoding: UTF-8 Roxygen: list(markdown = TRUE) RoxygenNote: 7.3.2 Config/pak/sysreqs: libglpk-dev libmagick++-dev gsfonts libicu-dev libxml2-dev libssl-dev zlib1g-dev Repository: https://bioc.r-universe.dev Date/Publication: 2026-04-28 13:00:35 UTC RemoteUrl: https://github.com/bioc/concordexR RemoteRef: HEAD RemoteSha: 3b93bdfd7a224aee10649d0e880910ba84fd332e NeedsCompilation: no Packaged: 2026-05-30 08:51:02 UTC; root Author: Kayla Jackson [aut, cre] (ORCID: ), A. Sina Booeshaghi [aut] (ORCID: ), Angel Galvez-Merchan [aut] (ORCID: ), Lambda Moses [aut] (ORCID: ), Alexandra Kim [ctb], Laura Luebbert [ctb] (ORCID: ), Lior Pachter [aut, rev, ths] (ORCID: ) Maintainer: Kayla Jackson