# -------------------------------------------- # CITATION file created with {cffr} R package # See also: https://docs.ropensci.org/cffr/ # -------------------------------------------- cff-version: 1.2.0 message: 'To cite package "cn.mops" in publications use:' type: software license: LGPL-2.0-or-later title: 'cn.mops: cn.mops - Mixture of Poissons for CNV detection in NGS data' version: 1.51.0 doi: 10.1093/nar/gks003 abstract: cn.mops (Copy Number estimation by a Mixture Of PoissonS) is a data processing pipeline for copy number variations and aberrations (CNVs and CNAs) from next generation sequencing (NGS) data. The package supplies functions to convert BAM files into read count matrices or genomic ranges objects, which are the input objects for cn.mops. cn.mops models the depths of coverage across samples at each genomic position. Therefore, it does not suffer from read count biases along chromosomes. Using a Bayesian approach, cn.mops decomposes read variations across samples into integer copy numbers and noise by its mixture components and Poisson distributions, respectively. cn.mops guarantees a low FDR because wrong detections are indicated by high noise and filtered out. cn.mops is very fast and written in C++. authors: - family-names: Klambauer given-names: Guenter - family-names: Povysil given-names: Gundula email: povysil@bioinf.jku.at preferred-citation: type: article title: 'cn.MOPS: Mixture of Poissons for Discovering Copy Number Variations in Next Generation Sequencing Data with a Low False Discovery Rate' authors: - family-names: Klambauer given-names: Guenter - family-names: Schwarzbauer given-names: Karin - family-names: Mayr given-names: Andreas - family-names: Mitterecker given-names: Andreas - family-names: Clevert given-names: Djork-Arne - family-names: Bodenhofer given-names: Ulrich - family-names: Hochreiter given-names: Sepp year: '2012' volume: '40' journal: Nucleic Acids Research doi: 10.1093/nar/gks003 url: http://nar.oxfordjournals.org/content/40/9/e69.abstract start: e69 repository: https://bioc.r-universe.dev url: http://www.bioinf.jku.at/software/cnmops/cnmops.html date-released: '2021-11-20' contact: - family-names: Povysil given-names: Gundula email: povysil@bioinf.jku.at