Package: clusterProfiler Type: Package Title: A Universal Enrichment Tool for Interpreting Omics Data Version: 4.21.0 Authors@R: c( person(given = "Guangchuang", family = "Yu", email = "guangchuangyu@gmail.com", role = c("aut", "cre", "cph"), comment = c(ORCID = "0000-0002-6485-8781")), person(given = "Li-Gen", family = "Wang", email = "reeganwang020@gmail.com", role = "ctb"), person(given = "Xiao", family = "Luo", email = "l77880853349@163.com", role = "ctb"), person(given = "Meijun", family = "Chen", email = "mjchen1996@outlook.com", role = "ctb"), person(given = "Giovanni", family = "Dall'Olio", email = "giovanni.dallolio@upf.edu", role = "ctb"), person(given = "Wanqian", family = "Wei", email = "altair_wei@outlook.com", role = "ctb"), person(given = "Chun-Hui", family = "Gao", email = "gaospecial@gmail.com", role = "ctb", comment = c(ORCID = "0000-0002-1445-7939")) ) Maintainer: Guangchuang Yu Description: A universal tool for interpreting functional characteristics of omics data. It supports Over-Representation Analysis (ORA) and Gene Set Enrichment Analysis (GSEA) for both coding and non-coding genomics data of thousands of species. It provides a unified and tidy interface to access, manipulate, and visualize enrichment results. A key capability is the simultaneous analysis and comparison of datasets from multiple treatments or time points. Furthermore, it integrates Large Language Model (LLM) capabilities to provide automated and insightful interpretation of enrichment results. Depends: R (>= 4.2.0) Imports: aisdk, AnnotationDbi, dplyr, enrichit (>= 0.1.1), enrichplot (>= 1.9.3), ggplot2, GO.db, GOSemSim (>= 2.27.2), gson (>= 0.0.7), httr, igraph, jsonlite, magrittr, methods, plyr, qvalue, rlang, stats, tidyr, utils, yulab.utils (>= 0.2.3) Suggests: AnnotationHub, BiocManager, DOSE, ggtangle, readr, org.Hs.eg.db, quarto, testthat VignetteBuilder: quarto ByteCompile: true License: Artistic-2.0 URL: https://yulab-smu.top/contribution-knowledge-mining/ BugReports: https://github.com/YuLab-SMU/clusterProfiler/issues Packaged: 2026-05-30 08:57:32 UTC; root biocViews: Annotation, Clustering, GeneSetEnrichment, GO, KEGG, MultipleComparison, Pathways, Reactome, Visualization Encoding: UTF-8 RoxygenNote: 7.3.3 Config/pak/sysreqs: libcairo2-dev cmake libfontconfig1-dev libfreetype6-dev libglpk-dev make libicu-dev libpng-dev libuv1-dev libxml2-dev libssl-dev zlib1g-dev Repository: https://bioc.r-universe.dev Date/Publication: 2026-04-28 12:35:12 UTC RemoteUrl: https://github.com/bioc/clusterProfiler RemoteRef: HEAD RemoteSha: 400f57a5dccaaa0a4ea5cb34caf2f3a2b2a6ea4b NeedsCompilation: no Author: Guangchuang Yu [aut, cre, cph] (ORCID: ), Li-Gen Wang [ctb], Xiao Luo [ctb], Meijun Chen [ctb], Giovanni Dall'Olio [ctb], Wanqian Wei [ctb], Chun-Hui Gao [ctb] (ORCID: )