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# CITATION file created with {cffr} R package
# See also: https://docs.ropensci.org/cffr/
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message: 'To cite package "cfTools" in publications use:'
type: software
title: 'cfTools: Informatics Tools for Cell-Free DNA Study'
version: 1.5.0
abstract: 'The cfTools R package provides methods for cell-free DNA (cfDNA) methylation
  data analysis to facilitate cfDNA-based studies. Given the methylation sequencing
  data of a cfDNA sample, for each cancer marker or tissue marker, we deconvolve the
  tumor-derived or tissue-specific reads from all reads falling in the marker region.
  Our read-based deconvolution algorithm exploits the pervasiveness of DNA methylation
  for signal enhancement, therefore can sensitively identify a trace amount of tumor-specific
  or tissue-specific cfDNA in plasma. cfTools provides functions for (1) cancer detection:
  sensitively detect tumor-derived cfDNA and estimate the tumor-derived cfDNA fraction
  (tumor burden); (2) tissue deconvolution: infer the tissue type composition and
  the cfDNA fraction of multiple tissue types for a plasma cfDNA sample. These functions
  can serve as foundations for more advanced cfDNA-based studies, including cancer
  diagnosis and disease monitoring.'
authors:
- family-names: Hu
  given-names: Ran
  email: huran@ucla.edu
  orcid: https://orcid.org/0000-0002-0563-8957
- family-names: Stackpole
  given-names: Mary Louisa
  orcid: https://orcid.org/0000-0003-4432-6718
- family-names: Li
  given-names: Shuo
  orcid: https://orcid.org/0000-0002-1960-6016
- family-names: Zhou
  given-names: Xianghong Jasmine
  email: XJZhou@mednet.ucla.edu
  orcid: https://orcid.org/0000-0002-4522-7490
- family-names: Li
  given-names: Wenyuan
  email: WenyuanLi@mednet.ucla.edu
  orcid: https://orcid.org/0000-0002-5029-8525
repository: https://bioc.r-universe.dev
repository-code: https://github.com/jasminezhoulab/cfTools
url: https://github.com/jasminezhoulab/cfTools
contact:
- family-names: Hu
  given-names: Ran
  email: huran@ucla.edu
  orcid: https://orcid.org/0000-0002-0563-8957