# ------------------------------------------------ # CITATION.cff file created with {cffr} R package # See also: https://docs.ropensci.org/cffr/ # ------------------------------------------------ cff-version: 1.2.0 message: 'To cite package "causalASCEND" in publications use:' type: software license: GPL-3.0-only title: 'causalASCEND: Scalable Two-Tier Causal Discovery for Multi-Omic Data' version: 0.99.5 abstract: Causal ASCEND (Ancestral Scalable Causal discovEry via iNherited Descent) infers ancestral (cause-before-effect) relations among downstream molecular variables, such as gene expression, when a layer of upstream variables, such as genotypes or methylation sites, is known to precede them. Each conditional independence test conditions only on a small, iteratively refined set of nearest ancestors instead of the whole upstream layer, so the number of tests grows polynomially with the number of variables. The package accepts matrices, SummarizedExperiment objects or a MultiAssayExperiment, and returns the ancestral relations with the rule and evidence behind each one. authors: - family-names: Asiedu given-names: Stephen email: stephen.asiedu@kcl.ac.uk orcid: https://orcid.org/0009-0005-8885-5381 - family-names: Watson given-names: David email: david.watson@kcl.ac.uk repository: https://bioc.r-universe.dev repository-code: https://github.com/SparkAILab/causalASCEND commit: 9104c90774ead6bbda65320363ca5ef0c136e922 url: https://github.com/SparkAILab/causalASCEND date-released: '2026-11-06' contact: - family-names: Asiedu given-names: Stephen email: stephen.asiedu@kcl.ac.uk orcid: https://orcid.org/0009-0005-8885-5381