Package: casper Version: 2.47.0 Date: 2026-03-12 Title: Characterization of Alternative Splicing Based on Paired-End Reads Authors@R: c(person(given = "David", family = "Rossell", role = c("aut", "cre"), email = "rosselldavid@gmail.com"), person(given = "Camille", family = "Stephan-Otto", role = "aut"), person(given = "Manuel", family = "Kroiss", role = "aut"), person(given = "Miranda", family = "Stobbe", role = "aut"), person(given = "Victor", family = "Pena", role = "aut")) Maintainer: David Rossell Depends: R (>= 3.6.0), Biobase, IRanges, methods, GenomicRanges Imports: BiocGenerics (>= 0.31.6), coda, EBarrays, gaga, gtools, Seqinfo, GenomicFeatures, limma, mgcv, Rsamtools, rtracklayer, S4Vectors (>= 0.9.25), sqldf, survival, txdbmaker, VGAM Enhances: parallel Description: Infer alternative splicing from paired-end RNA-seq data. The model is based on counting paths across exons, rather than pairwise exon connections, and estimates the fragment size and start distributions non-parametrically, which improves estimation precision. License: GPL (>=2) LazyLoad: yes Collate: GenericDefs.R ClassDefinitions.R asymmetryCheck.R calcDenovo.R calcExp.R casperVignettes.R createDenovoGenome.R genePlot.R getDistrs.R getRoc.R denovoExpr.R makeTranscriptDbFromGFF.R mergeBatches.R mergeExp.R modelPrior.R pathCounts.R probNonEquiv.R procBam.R procGenome.R qqnormGenomeWide.R relexprByGene.R rmShortInserts.R simMultSamples.R simPost.R simReads.R splitGenomeByLength.R truncnorm.R wrapKnown.R checks.R wrapDenovo.R biocViews: ImmunoOncology, GeneExpression, DifferentialExpression, Transcription, RNASeq, Sequencing Config/pak/sysreqs: make libbz2-dev libicu-dev liblzma-dev libpng-dev libxml2-dev libssl-dev xz-utils zlib1g-dev Repository: https://bioc.r-universe.dev Date/Publication: 2026-04-28 12:37:14 UTC RemoteUrl: https://github.com/bioc/casper RemoteRef: HEAD RemoteSha: 2471cc4deb01d422191faccc332d926cef3d528d NeedsCompilation: yes Packaged: 2026-07-15 04:51:10 UTC; root Author: David Rossell [aut, cre], Camille Stephan-Otto [aut], Manuel Kroiss [aut], Miranda Stobbe [aut], Victor Pena [aut]