Package: blase Title: Bulk Linkage Analysis for Single-cell Experiments Version: 1.3.2 Authors@R: c( person("Andrew", "McCluskey", , "2117532m@student.gla.ac.uk", role = c("aut", "cre"), comment = c(ORCID = "0009-0004-4187-799X")), person("Toby", "Kettlewell", , , role = c("aut"), comment = c(ORCID = "0009-0001-1225-3318")), person("Adrian M.", "Smith", , , role = c("aut"), comment = c(ORCID="0000-0001-8833-2330")), person("Rhiannon", "Kundu", , , role = c("aut"), comment = c(ORCID="0000-0003-3970-5860")), person("David A.", "Gunn", , , role = c("aut"), comment = c(ORCID="0000-0001-9866-3221")), person("Thomas D.", "Otto", , , role=c("aut","ths"), comment=c(ORCID = "0000-0002-1246-7404"))) Description: BLASE is a method for finding where bulk RNA-seq data lies on a single-cell pseudotime trajectory. It uses a fast and understandable approach based on Spearman correlation, with bootstrapping to provide confidence. BLASE can be used to "date" bulk RNA-seq data, annotate cell types in scRNA-seq, and help correct for developmental phenotype differences in bulk RNA-seq experiments. License: GPL (>= 3) Encoding: UTF-8 Roxygen: list(markdown = TRUE) RoxygenNote: 7.3.3 biocViews: Transcriptomics, SingleCell, Sequencing, GeneExpression, Transcription, RNASeq, TimeCourse, CellBiology, Software, CellBasedAssays Imports: SummarizedExperiment, SingleCellExperiment, ggplot2, viridis, patchwork, Matrix, scater, methods, rlang, BiocParallel, boot, dplyr, mgcv, stats, MatrixGenerics, Seurat (>= 4.0.0), lsa Suggests: knitr, rmarkdown, testthat (>= 3.2.3), covr, tradeSeq, scran, slingshot, tools, reshape2, plyr, fs, sparseMatrixStats, ggVennDiagram, uwot, BiocStyle, DelayedMatrixStats, limma Config/testthat/edition: 3 VignetteBuilder: knitr URL: https://andrewmccluskey-uog.github.io/blase/ BugReports: https://andrewmccluskey-uog.github.io/blase/issues Depends: R (>= 4.5.0) LazyData: false Config/pak/sysreqs: cmake libglpk-dev make libicu-dev libpng-dev libuv1-dev libxml2-dev libssl-dev python3 zlib1g-dev Repository: https://bioc.r-universe.dev Date/Publication: 2026-07-14 08:30:54 UTC RemoteUrl: https://github.com/bioc/blase RemoteRef: HEAD RemoteSha: 843de9e652f0387ff7bafc9364fa4c365e2b45b1 NeedsCompilation: no Packaged: 2026-07-14 09:44:06 UTC; root Author: Andrew McCluskey [aut, cre] (ORCID: ), Toby Kettlewell [aut] (ORCID: ), Adrian M. Smith [aut] (ORCID: ), Rhiannon Kundu [aut] (ORCID: ), David A. Gunn [aut] (ORCID: ), Thomas D. Otto [aut, ths] (ORCID: ) Maintainer: Andrew McCluskey <2117532m@student.gla.ac.uk>