Backman TWH, Girke T (2016) bioassayR: Cross-Target Analysis of Small Molecule Bioactivity. J. Chem. Inf. Model. 56: 1237-1242,<doi:10.1021/acs.jcim.6b00109>.
Corresponding BibTeX entry:
@Article{,
title = {bioassayR: {Cross-Target} Analysis of Small Molecule
Bioactivity},
author = {{Backman} and Tyler William H and {Girke} and {Thomas}},
abstract = {Despite a large and rapidly growing body of small
molecule bioactivity screens available in the public domain,
systematic leverage of the data to assess target druggability and
compound selectivity has been confounded by a lack of suitable
cross-target analysis software. We have developed bioassayR, a
computational tool that enables simultaneous analysis of
thousands of bioassay experiments performed over a diverse set of
compounds and biological targets. Unique features include support
for large-scale cross-target analyses of both public and custom
bioassays, generation of high throughput screening fingerprints
(HTSFPs), and an optional preloaded database that provides access
to a substantial portion of publicly available bioactivity data.
bioassayR is implemented as an open-source R/Bioconductor package
available from https://bioconductor.org/packages/bioassayR/ .},
journal = {J. Chem. Inf. Model.},
volume = {56},
number = {7},
pages = {1237--1242},
month = {jul},
year = {2016},
language = {en},
doi = {10.1021/acs.jcim.6b00109},
url = {https://doi.org/10.1021/acs.jcim.6b00109},
}