{
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  "Package": "wppi",
  "Type": "Package",
  "Title": "Weighting protein-protein interactions",
  "Version": "1.21.0",
  "Authors@R": "c(\nperson(\ngiven = \"Ana\",\nfamily = \"Galhoz\",\nrole = c(\"cre\", \"aut\"),\nemail = \"ana.galhoz@helmholtz-muenchen.de\",\ncomment = c(ORCID = \"0000-0001-7402-5292\")),\nperson(\ngiven = \"Denes\",\nfamily = \"Turei\",\nrole = \"aut\",\nemail = \"turei.denes@gmail.com\",\ncomment = c(ORCID = \"0000-0002-7249-9379\")),\nperson(\ngiven = \"Michael\",\nfamily = \"P. Menden\",\nrole = \"aut\",\nemail = \"michael.menden@helmholtz-muenchen.de\",\ncomment = c(ORCID = \"0000-0003-0267-5792\")),\n#\n# Copyright holders\nperson(\"Albert\", \"Krewinkel\", role = c(\"ctb\", \"cph\"),\ncomment = \"pagebreak Lua filter\")\n)",
  "Description": "Protein-protein interaction data is essential for omics\ndata analysis and modeling. Database knowledge is general, not\nspecific for cell type, physiological condition or any other\ncontext determining which connections are functional and\ncontribute to the signaling. Functional annotations such as\nGene Ontology and Human Phenotype Ontology might help to\nevaluate the relevance of interactions. This package predicts\nfunctional relevance of protein-protein interactions based on\nfunctional annotations such as Human Protein Ontology and Gene\nOntology, and prioritizes genes based on network topology,\nfunctional scores and a path search algorithm.",
  "License": "MIT + file LICENSE",
  "URL": "https://github.com/AnaGalhoz37/wppi",
  "BugReports": "https://github.com/AnaGalhoz37/wppi/issues",
  "biocViews": "GraphAndNetwork, Network, Pathways, Software, GeneSignaling,\nGeneTarget, SystemsBiology, Transcriptomics, Annotation",
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  "Repository": "https://bioc.r-universe.dev",
  "Date/Publication": "2026-04-28 12:55:38 UTC",
  "RemoteUrl": "https://github.com/bioc/wppi",
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  "Packaged": {
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    "User": "root"
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  "Author": "Ana Galhoz [cre, aut] (ORCID: <https://orcid.org/0000-0001-7402-5292>),\nDenes Turei [aut] (ORCID: <https://orcid.org/0000-0002-7249-9379>),\nMichael P. Menden [aut] (ORCID:\n<https://orcid.org/0000-0003-0267-5792>),\nAlbert Krewinkel [ctb, cph] (pagebreak Lua filter)",
  "Maintainer": "Ana Galhoz <ana.galhoz@helmholtz-muenchen.de>",
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