{
  "_id": "6a1aee891d7bb097a09f5a20",
  "Package": "tomoda",
  "Title": "Tomo-seq data analysis",
  "Version": "1.23.0",
  "Authors@R": "person(given = \"Wendao\",\nfamily = \"Liu\",\nrole = c(\"aut\", \"cre\"),\nemail = \"liuwd15@tsinghua.org.cn\",\ncomment = c(ORCID = \"0000-0002-5124-9338\"))",
  "Description": "This package provides many easy-to-use methods to analyze\nand visualize tomo-seq data. The tomo-seq technique is based on\ncryosectioning of tissue and performing RNA-seq on consecutive\nsections. (Reference: Kruse F, Junker JP, van Oudenaarden A,\nBakkers J. Tomo-seq: A method to obtain genome-wide expression\ndata with spatial resolution. Methods Cell Biol.\n2016;135:299-307. doi:10.1016/bs.mcb.2016.01.006) The main\npurpose of the package is to find zones with similar\ntranscriptional profiles and spatially expressed genes in a\ntomo-seq sample. Several visulization functions are available\nto create easy-to-modify plots.",
  "License": "MIT + file LICENSE",
  "Encoding": "UTF-8",
  "Roxygen": "list(markdown = TRUE)",
  "RoxygenNote": "7.1.2",
  "URL": "https://github.com/liuwd15/tomoda",
  "BugReports": "https://github.com/liuwd15/tomoda/issues",
  "biocViews": "GeneExpression, Sequencing, RNASeq, Transcriptomics,\nSpatial, Clustering, Visualization",
  "VignetteBuilder": "knitr",
  "Config/pak/sysreqs": "libicu-dev libpng-dev libssl-dev python3 zlib1g-dev",
  "Repository": "https://bioc.r-universe.dev",
  "Date/Publication": "2026-04-28 12:53:56 UTC",
  "RemoteUrl": "https://github.com/bioc/tomoda",
  "RemoteRef": "HEAD",
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  "NeedsCompilation": "no",
  "Packaged": {
    "Date": "2026-05-30 09:41:22 UTC",
    "User": "root"
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  "Author": "Wendao Liu [aut, cre] (ORCID: <https://orcid.org/0000-0002-5124-9338>)",
  "Maintainer": "Wendao Liu <liuwd15@tsinghua.org.cn>",
  "MD5sum": "90c91d04aa2b48f54dc4041cd999ab72",
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  "_published": "2026-05-30T14:04:57.591Z",
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    "author": "A Wokaty <andres.wokaty@sph.cuny.edu>",
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    "description": "Software for the analysis and comprehension of high-throughput genomic data"
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    "findPeak",
    "findPeakGene",
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    "geneEmbedPlot",
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    "runUMAP",
    "scaleTomo",
    "tomoMatrix",
    "tomoSummarizedExperiment"
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      "title": "A raw read count matrix of zebrafish injured heart.",
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        "array"
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        "X2",
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      "page": "corHeatmap",
      "title": "Correlation heatmap of sections",
      "topics": [
        "corHeatmap"
      ]
    },
    {
      "page": "createTomo",
      "title": "Create an object representing tomo-seq data",
      "topics": [
        "createTomo",
        "createTomo,matrix-method",
        "createTomo,missing-method",
        "createTomo,SummarizedExperiment-method"
      ]
    },
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      "page": "embedPlot",
      "title": "Embedding plot for sections",
      "topics": [
        "embedPlot"
      ]
    },
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      "title": "Expression heatmap",
      "topics": [
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      ]
    },
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      "title": "Find peak in a vector",
      "topics": [
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      ]
    },
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      "title": "Find peak genes",
      "topics": [
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      ]
    },
    {
      "page": "geneCorHeatmap",
      "title": "Correlation heatmap of genes",
      "topics": [
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      ]
    },
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      "title": "Embedding plot for genes",
      "topics": [
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    },
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      "title": "Hierarchical clustering across sections",
      "topics": [
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      ]
    },
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      "title": "K-Means clustering across sections",
      "topics": [
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    },
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      "title": "Line plot for expression traces",
      "topics": [
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      ]
    },
    {
      "page": "normalizeTomo",
      "title": "Normalize data",
      "topics": [
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      "title": "Perform PCA",
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      "title": "Create an object from matrix",
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    },
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