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  "Package": "tidyexposomics",
  "Title": "Integrated Exposure-Omics Analysis Powered by Tidy Principles",
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  "Authors@R": "c(\nperson(given = \"Jason\",\nfamily  = \"Laird\",\nemail = \"jasonlaird5353@gmail.com\",\nrole = c(\"aut\", \"cre\"),\ncomment = c(ORCID = \"0009-0000-5994-2236\")\n),\nperson(given = \"Thomas\",\nfamily  = \"Hartung\",\nemail = \"thartun1@jhu.edu\",\nrole = c(\"ctb\"),\ncomment = c(ORCID = \"0000-0003-1359-7689\")\n),\nperson(given = \"Fenna\",\nfamily  = \"Sillé\",\nemail = \"fsille1@jhu.edu\",\nrole = c(\"ctb\"),\ncomment = c(ORCID = \"0000-0003-4305-2049\")\n),\nperson(given = \"Alexandra\",\nfamily  = \"Maertens\",\nemail = \"amaerte1@jhu.edu\",\nrole = c(\"ctb\"),\ncomment = c(ORCID = \"0000-0002-2077-2011\")\n),\nperson(\"JHU Discovery Award\", role = \"fnd\")\n)",
  "Description": "The tidyexposomics package is designed to facilitate the\nintegration of exposure and omics data to identify\nexposure-omics associations. We structure our commands to fit\ninto the tidyverse framework, where commands are designed to be\nsimplified and intuitive. Here we provide functionality to\nperform quality control, sample and exposure association\nanalysis, differential abundance analysis, multi-omics\nintegration, and functional enrichment analysis.",
  "License": "MIT + file LICENSE",
  "URL": "https://bionomad.github.io/tidyexposomics/",
  "BugReports": "https://github.com/BioNomad/tidyexposomics/issues",
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  "Repository": "https://bioc.r-universe.dev",
  "Date/Publication": "2026-04-28 13:06:08 UTC",
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  "Author": "Jason Laird [aut, cre] (ORCID: <https://orcid.org/0009-0000-5994-2236>),\nThomas Hartung [ctb] (ORCID: <https://orcid.org/0000-0003-1359-7689>),\nFenna Sillé [ctb] (ORCID: <https://orcid.org/0000-0003-4305-2049>),\nAlexandra Maertens [ctb] (ORCID:\n<https://orcid.org/0000-0002-2077-2011>),\nJHU Discovery Award [fnd]",
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    "create_exposomicset",
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    "pivot_feature",
    "pivot_sample",
    "plot_association",
    "plot_circos_correlation",
    "plot_correlation_summary",
    "plot_correlation_tile",
    "plot_enrichment",
    "plot_exposure_impact",
    "plot_exposure_omics_association",
    "plot_exposures",
    "plot_factor_summary",
    "plot_manhattan",
    "plot_missing",
    "plot_network",
    "plot_normality_summary",
    "plot_pca",
    "plot_sample_clusters",
    "plot_sensitivity_summary",
    "plot_top_factor_features",
    "plot_volcano",
    "run_association",
    "run_cluster_samples",
    "run_correlation",
    "run_create_network",
    "run_differential_abundance",
    "run_enrichment",
    "run_exposome_score",
    "run_exposure_impact",
    "run_exposure_omics_association",
    "run_factor_overlap",
    "run_impute_missing",
    "run_multiomics_integration",
    "run_normality_check",
    "run_pca",
    "run_pipeline_summary",
    "run_sensitivity_analysis",
    "run_summarize_exposures",
    "transform_exposure"
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      "name": "tidyexposomics_example",
      "title": "Example exposome multi-omics dataset",
      "object": "tidyexposomics_example",
      "file": "tidyexposomics_example.RData",
      "class": [
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      ],
      "fields": [],
      "table": false,
      "tojson": true
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      "page": "build_ont_annot_app",
      "title": "Build the Ontology Annotation Shiny app",
      "topics": [
        "build_ont_annot_app"
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    },
    {
      "page": "create_exposomicset",
      "title": "Create an Exposomicset Object",
      "topics": [
        "create_exposomicset"
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    },
    {
      "page": "download_dataset",
      "title": "Download and cache a tidyexposomics dataset",
      "topics": [
        "download_dataset"
      ]
    },
    {
      "page": "extract_omics_exposure_df",
      "title": "Extract Merged Omics and Exposure Data Frame",
      "topics": [
        "extract_omics_exposure_df"
      ]
    },
    {
      "page": "extract_results",
      "title": "Extract Results from 'MultiAssayExperiment' Metadata",
      "topics": [
        "extract_results"
      ]
    },
    {
      "page": "extract_results_excel",
      "title": "Export tidyexposomics Results to Excel",
      "topics": [
        "extract_results_excel"
      ]
    },
    {
      "page": "extract_top_factor_features",
      "title": "Extract Top Contributing Features for Factors",
      "topics": [
        "extract_top_factor_features"
      ]
    },
    {
      "page": "filter_missing",
      "title": "Filter Features and Variables with High Missingness",
      "topics": [
        "filter_missing"
      ]
    },
    {
      "page": "filter_non_normal",
      "title": "Filter Non-Normal Exposure Variables",
      "topics": [
        "filter_non_normal"
      ]
    },
    {
      "page": "filter_omics",
      "title": "Filter low-quality features in omics assays",
      "topics": [
        "filter_omics"
      ]
    },
    {
      "page": "filter_sample_outliers",
      "title": "Filter Sample Outliers",
      "topics": [
        "filter_sample_outliers"
      ]
    },
    {
      "page": "load_annotation_data",
      "title": "Load Ontology Data",
      "topics": [
        "load_annotation_data"
      ]
    },
    {
      "page": "make_example_data",
      "title": "Generate Example Data for Testing",
      "topics": [
        "make_example_data"
      ]
    },
    {
      "page": "pivot_exp",
      "title": "Pivot a selected omics dataset from a MultiAssayExperiment into tidybulk format",
      "topics": [
        "pivot_exp"
      ]
    },
    {
      "page": "pivot_feature",
      "title": "Extract Feature Metadata from a MultiAssayExperiment",
      "topics": [
        "pivot_feature"
      ]
    },
    {
      "page": "pivot_sample",
      "title": "Extract Sample Metadata from MultiAssayExperiment or SummarizedExperiment",
      "topics": [
        "pivot_sample"
      ]
    },
    {
      "page": "plot_association",
      "title": "Plot Association Results (Unified Forest Plot)",
      "topics": [
        "plot_association"
      ]
    },
    {
      "page": "plot_circos_correlation",
      "title": "Plot Circular Network of Exposure Relationships",
      "topics": [
        "plot_circos_correlation"
      ]
    },
    {
      "page": "plot_correlation_summary",
      "title": "Plot Correlation Summary from Exposure-Feature Correlations",
      "topics": [
        "plot_correlation_summary"
      ]
    },
    {
      "page": "plot_correlation_tile",
      "title": "Plot Correlation Tilemap",
      "topics": [
        "plot_correlation_tile"
      ]
    },
    {
      "page": "plot_enrichment",
      "title": "Plot Enrichment Results from exposomicset",
      "topics": [
        "plot_enrichment"
      ]
    },
    {
      "page": "plot_exposure_impact",
      "title": "Plot Exposure Impact on Network Centrality Metrics",
      "topics": [
        "plot_exposure_impact"
      ]
    },
    {
      "page": "plot_exposure_omics_association",
      "title": "Plot Exposure-Omics Associations",
      "topics": [
        "plot_exposure_omics_association"
      ]
    },
    {
      "page": "plot_exposures",
      "title": "Plot Exposure Distributions by Category or Group",
      "topics": [
        "plot_exposures"
      ]
    },
    {
      "page": "plot_factor_summary",
      "title": "Plot Summary of Factor Contributions from Multi-Omics Integration",
      "topics": [
        "plot_factor_summary"
      ]
    },
    {
      "page": "plot_manhattan",
      "title": "Plot a Manhattan-style ExWAS summary across omics categories",
      "topics": [
        "plot_manhattan"
      ]
    },
    {
      "page": "plot_missing",
      "title": "Plot Missing Data Across Exposure and Omic Layers",
      "topics": [
        "plot_missing"
      ]
    },
    {
      "page": "plot_network",
      "title": "Plot Network Graph of Features or Exposures",
      "topics": [
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      ]
    },
    {
      "page": "plot_normality_summary",
      "title": "Plot Normality Summary of Exposure Variables",
      "topics": [
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      "title": "Plot PCA Results for Features and Samples",
      "topics": [
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      "title": "Plot Sample Clusters",
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