{
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  "Title": "Hits Selection for Synthetic Lethal RNAi Screen Data",
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  "Authors@R": "person(given = \"Chunxuan\", family = \"Shao\", role = c(\"aut\", \"cre\"), email = \"chunxuan@outlook.com\")",
  "Description": "Select hits from synthetic lethal RNAi screen data. For\nexample, there are two identical celllines except one gene is\nknocked-down in one cellline. The interest is to find genes\nthat lead to stronger lethal effect when they are knocked-down\nfurther by siRNA. Quality control and various visualisation\ntools are implemented. Four different algorithms could be used\nto pick up the interesting hits. This package is designed based\non 384 wells plates, but may apply to other platforms with\nproper configuration.",
  "License": "GPL-3",
  "biocViews": "ImmunoOncology, CellBasedAssays, QualityControl,\nPreprocessing, Visualization, FeatureExtraction",
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  "Repository": "https://bioc.r-universe.dev",
  "Date/Publication": "2026-04-28 12:41:40 UTC",
  "RemoteUrl": "https://github.com/bioc/synlet",
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  "Packaged": {
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    "User": "root"
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  "Author": "Chunxuan Shao [aut, cre]",
  "Maintainer": "Chunxuan Shao <chunxuan@outlook.com>",
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    "author": "A Wokaty <andres.wokaty@sph.cuny.edu>",
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      "title": "Synthetic lethal RNAi screen example data.",
      "object": "example_dt",
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      "class": [
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        "data.frame"
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        "MASTER_PLATE",
        "WELL_CONTENT_NAME",
        "EXPERIMENT_TYPE",
        "EXPERIMENT_MODIFICATION",
        "ROW_NAME",
        "COL_NAME",
        "READOUT"
      ],
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      "title": "Calculate B-score",
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    },
    {
      "page": "example_dt",
      "title": "Synthetic lethal RNAi screen example data.",
      "topics": [
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      ]
    },
    {
      "page": "madSelect",
      "title": "Select hits basing on median +- k*MAD",
      "topics": [
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      ]
    },
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      "title": "Heatmap of all plates",
      "topics": [
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    },
    {
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      "topics": [
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      ]
    },
    {
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      "title": "Select hits by RSA",
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    },
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      ]
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      "created": "2015-08-06 17:36:37",
      "modified": "2023-02-01 17:37:18",
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