{
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  "Title": "Spillover Compensation in Mass Cytometry Data",
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  "Authors@R": "c(\nperson(\"Marco\", \"Guazzini\",\nemail= \"m.guazzini@student.maastrichtuniversity.nl\",\nrole = c(\"aut\", \"cre\"), comment = c(ORCID = \"0009-0007-8111-5772\")),\nperson(\"Alexander G.\", \"Reisach\" ,\nemail = \"alexander.reisach@u-paris.fr\",\nrole = \"aut\", comment = c(ORCID = \"0009-0003-5057-6278\")),\nperson(\"Sebastian\", \"Weichwald\",\nemail = \"sweichwald@math.ku.dk\",\nrole = \"aut\", comment = c(ORCID = \"0000-0003-0169-7244\")),\nperson(\"Christof\", \"Seiler\",\nemail = \"christof.seiler@maastrichtuniversity.nl\",\nrole = \"aut\", comment = c(ORCID = \"0000-0001-8802-3642\")))",
  "Description": "Channel interference in mass cytometry can cause spillover\nand may result in miscounting of protein markers. We develop a\nnonparametric finite mixture model and use the mixture\ncomponents to estimate the probability of spillover. We\nimplement our method using expectation-maximization to fit the\nmixture model.",
  "biocViews": "FlowCytometry, ImmunoOncology, MassSpectrometry,\nPreprocessing, SingleCell, Software, StatisticalMethod,\nVisualization, Regression",
  "License": "LGPL-3",
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  "Date/Publication": "2026-04-28 13:02:05 UTC",
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  "Author": "Marco Guazzini [aut, cre] (ORCID:\n<https://orcid.org/0009-0007-8111-5772>),\nAlexander G. Reisach [aut] (ORCID:\n<https://orcid.org/0009-0003-5057-6278>),\nSebastian Weichwald [aut] (ORCID:\n<https://orcid.org/0000-0003-0169-7244>),\nChristof Seiler [aut] (ORCID: <https://orcid.org/0000-0001-8802-3642>)",
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