{
  "_id": "6a61cbae768d0b54cfc78a25",
  "Package": "scTHI",
  "Title": "Indentification of significantly activated ligand-receptor\ninteractions across clusters of cells from single-cell RNA\nsequencing data",
  "Version": "1.25.0",
  "Authors@R": "c(person(\"Francesca Pia\", \"Caruso\", email = \"francescapia.caruso@gmail.com\", role = c(\"aut\")),\nperson(\"Michele\", \"Ceccarelli\", email = \"m.ceccarelli@gmail.com\", role = c(\"aut\", \"cre\")))",
  "Description": "scTHI is an R package to identify active pairs of\nligand-receptors from single cells in order to study,among\nothers, tumor-host interactions. scTHI contains a set of\nsignatures to classify cells from the tumor microenvironment.",
  "License": "GPL-2",
  "Encoding": "UTF-8",
  "RoxygenNote": "6.1.1.9000",
  "VignetteBuilder": "knitr",
  "biocViews": "Software,SingleCell",
  "BugReports": "https://github.com/miccec/scTHI/issues",
  "Repository": "https://bioc.r-universe.dev",
  "Date/Publication": "2026-04-28 12:52:00 UTC",
  "RemoteUrl": "https://github.com/bioc/scTHI",
  "RemoteRef": "HEAD",
  "RemoteSha": "d2fa1dc894d94d3498a26a1f8c7bf0875d1f22ee",
  "NeedsCompilation": "no",
  "Packaged": {
    "Date": "2026-07-23 07:56:45 UTC",
    "User": "root"
  },
  "Author": "Francesca Pia Caruso [aut],\nMichele Ceccarelli [aut, cre]",
  "Maintainer": "Michele Ceccarelli <m.ceccarelli@gmail.com>",
  "_user": "bioc",
  "_type": "src",
  "_file": "scTHI_1.25.0.tar.gz",
  "_fileid": "https://r2.ropensci.org/b2d9c95f2df5952fcc95b5e2aef9363a03e4cfdd6475ac8097972aa0b6258fbc",
  "_filesize": 613322,
  "_sha256": "b2d9c95f2df5952fcc95b5e2aef9363a03e4cfdd6475ac8097972aa0b6258fbc",
  "_expires": "2026-10-31T08:07:08.000Z",
  "_created": "2026-07-23T07:56:45.000Z",
  "_published": "2026-07-23T08:07:09.828Z",
  "_bioccheck": {
    "error": 0,
    "warning": 1,
    "note": 12
  },
  "_host": "GitHub-Actions",
  "_buildurl": "https://github.com/r-universe/bioc/actions/runs/29989524003",
  "_status": "success",
  "_upstream": "https://github.com/bioc/scTHI",
  "_commit": {
    "id": "d2fa1dc894d94d3498a26a1f8c7bf0875d1f22ee",
    "author": "A Wokaty <andres.wokaty@sph.cuny.edu>",
    "committer": "A Wokaty <andres.wokaty@sph.cuny.edu>",
    "message": "bump x.y.z version to odd y following creation of RELEASE_3_23 branch\n",
    "time": 1777380720
  },
  "_maintainer": {
    "name": "Michele Ceccarelli",
    "email": "m.ceccarelli@gmail.com",
    "login": "miccec",
    "twitter": "@mceccarelli",
    "description": "\n    Professor at University of Miami\n",
    "uuid": 2706649
  },
  "_distro": "resolute",
  "_jobs": [
    {
      "job": 89149587465,
      "time": 144,
      "config": "bioc-checks",
      "r": "4.6.1",
      "check": "WARNING",
      "artifact": "8556586014"
    },
    {
      "job": 89149587476,
      "time": 189,
      "config": "linux-devel-x86_64",
      "r": "4.7.0",
      "check": "OK",
      "artifact": "8556601466"
    },
    {
      "job": 89149587457,
      "time": 222,
      "config": "linux-release-x86_64",
      "r": "4.6.1",
      "check": "OK",
      "artifact": "8556612734"
    },
    {
      "job": 89149587521,
      "time": 110,
      "config": "macos-oldrel-arm64",
      "r": "4.5.3",
      "check": "OK",
      "artifact": "8556574870"
    },
    {
      "job": 89149587474,
      "time": 113,
      "config": "macos-release-arm64",
      "r": "4.6.1",
      "check": "OK",
      "artifact": "8556575866"
    },
    {
      "job": 89148973145,
      "time": 235,
      "config": "source",
      "r": "4.6.1",
      "check": "OK",
      "artifact": "8556537428"
    },
    {
      "job": 89149587441,
      "time": 115,
      "config": "wasm-release",
      "r": "4.6.0",
      "check": "OK",
      "artifact": "8556576278"
    },
    {
      "job": 89149587488,
      "time": 125,
      "config": "windows-devel-x86_64",
      "r": "4.7.0",
      "check": "OK",
      "artifact": "8556579555"
    },
    {
      "job": 89149587478,
      "time": 162,
      "config": "windows-oldrel-x86_64",
      "r": "4.5.3",
      "check": "OK",
      "artifact": "8556593452"
    },
    {
      "job": 89149587507,
      "time": 138,
      "config": "windows-release-x86_64",
      "r": "4.6.1",
      "check": "OK",
      "artifact": "8556585299"
    }
  ],
  "_registered": true,
  "_dependencies": [
    {
      "package": "R",
      "version": ">= 4.0",
      "role": "Depends"
    },
    {
      "package": "BiocParallel",
      "role": "Imports"
    },
    {
      "package": "Rtsne",
      "role": "Imports"
    },
    {
      "package": "grDevices",
      "role": "Imports"
    },
    {
      "package": "graphics",
      "role": "Imports"
    },
    {
      "package": "stats",
      "role": "Imports"
    },
    {
      "package": "scTHI.data",
      "role": "Suggests"
    },
    {
      "package": "knitr",
      "role": "Suggests"
    },
    {
      "package": "rmarkdown",
      "role": "Suggests"
    },
    {
      "package": "BiocStyle",
      "role": "Suggests"
    }
  ],
  "_owner": "bioc",
  "_selfowned": true,
  "_usedby": 0,
  "_updates": [
    {
      "week": "2025-44",
      "n": 2
    },
    {
      "week": "2026-18",
      "n": 2
    }
  ],
  "_tags": [],
  "_bioc": [
    {
      "branch": "devel",
      "version": "1.25.0",
      "bioc": "3.24"
    },
    {
      "branch": "release",
      "version": "1.24.0",
      "bioc": "3.23"
    }
  ],
  "_topics": [
    "software",
    "singlecell"
  ],
  "_stars": 6,
  "_contributors": [
    {
      "user": "miccec",
      "count": 65,
      "uuid": 2706649
    },
    {
      "user": "fpcaruso",
      "count": 1,
      "uuid": 49145177
    }
  ],
  "_userbio": {
    "uuid": 2286807,
    "type": "organization",
    "name": "Bioconductor",
    "followers": 450,
    "description": "Software for the analysis and comprehension of high-throughput genomic data"
  },
  "_downloads": {
    "count": 331,
    "source": "https://www.bioconductor.org/packages/stats/bioc/scTHI"
  },
  "_mentions": 1,
  "_devurl": "https://github.com/miccec/scthi",
  "_searchresults": 2,
  "_rbuild": "4.6.1",
  "_assets": [
    "extra/citation.cff",
    "extra/citation.html",
    "extra/citation.json",
    "extra/citation.txt",
    "extra/contents.json",
    "extra/NEWS.html",
    "extra/NEWS.txt",
    "extra/scTHI.html",
    "manual.pdf"
  ],
  "_homeurl": "https://github.com/miccec/scthi",
  "_realowner": "bioc",
  "_cranurl": false,
  "_exports": [
    "scTHI_plotCluster",
    "scTHI_plotPairs",
    "scTHI_plotResult",
    "scTHI_runTsne",
    "scTHI_score",
    "TME_classification",
    "TME_plot"
  ],
  "_help": [
    {
      "page": "scTHI",
      "title": "single cell Tumor Hist Interaction (scTHI)",
      "topics": [
        "scTHI-package",
        "scTHI"
      ]
    },
    {
      "page": "scTHI_plotCluster",
      "title": "scTHI_plotCluster",
      "topics": [
        "scTHI_plotCluster"
      ]
    },
    {
      "page": "scTHI_plotPairs",
      "title": "scTHI_plotPairs",
      "topics": [
        "scTHI_plotPairs"
      ]
    },
    {
      "page": "scTHI_plotResult",
      "title": "scTHI_plotResult",
      "topics": [
        "scTHI_plotResult"
      ]
    },
    {
      "page": "scTHI_runTsne",
      "title": "scTHI_runTsne",
      "topics": [
        "scTHI_runTsne"
      ]
    },
    {
      "page": "scTHI_score",
      "title": "scTHI_score",
      "topics": [
        "scTHI_score"
      ]
    },
    {
      "page": "TME_classification",
      "title": "TME_classification",
      "topics": [
        "TME_classification"
      ]
    },
    {
      "page": "TME_plot",
      "title": "TME_plot",
      "topics": [
        "TME_plot"
      ]
    }
  ],
  "_rundeps": [
    "BH",
    "BiocParallel",
    "codetools",
    "cpp11",
    "formatR",
    "futile.logger",
    "futile.options",
    "lambda.r",
    "Rcpp",
    "Rtsne",
    "snow"
  ],
  "_vignettes": [
    {
      "source": "vignette.Rmd",
      "filename": "vignette.html",
      "title": "Using scTHI",
      "author": "Michele Ceccarelli, Francesca Pia Caruso",
      "engine": "knitr::rmarkdown",
      "headings": [
        "Introduction",
        "Installation",
        "Examples",
        "Analysis of H3K27M glioma from Fibin et al. Science 2018",
        "Input Data",
        "Run scTHI.score",
        "Tumor microenvironment classification",
        "Session Info",
        "References"
      ],
      "created": "2019-04-16 14:36:13",
      "modified": "2023-04-20 09:00:06",
      "commits": 5
    }
  ],
  "_score": 4.079181246047625,
  "_indexed": true,
  "_nocasepkg": "scthi",
  "_universes": [
    "bioc",
    "miccec"
  ],
  "_binaries": [
    {
      "r": "4.7.0",
      "os": "linux",
      "version": "1.25.0",
      "date": "2026-07-23T07:59:29.000Z",
      "distro": "resolute",
      "commit": "d2fa1dc894d94d3498a26a1f8c7bf0875d1f22ee",
      "fileid": "https://r2.ropensci.org/77671ecacf09b94d30b4dacc4a3c0a0140118ee868edfb52cdec2bfa13a6239e",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/bioc/actions/runs/29989524003"
    },
    {
      "r": "4.6.1",
      "os": "linux",
      "version": "1.25.0",
      "date": "2026-07-23T07:59:59.000Z",
      "distro": "resolute",
      "commit": "d2fa1dc894d94d3498a26a1f8c7bf0875d1f22ee",
      "fileid": "https://r2.ropensci.org/f0848a8fbeb5bb203999494faaa9f8fa3f398e33fc8c0bd54c5b9cec542e6c89",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/bioc/actions/runs/29989524003"
    },
    {
      "r": "4.5.3",
      "os": "mac",
      "version": "1.25.0",
      "date": "2026-07-23T07:58:17.000Z",
      "commit": "d2fa1dc894d94d3498a26a1f8c7bf0875d1f22ee",
      "fileid": "https://r2.ropensci.org/3a005d072ebac9ca14bfed383016f6e1e6f2fd600198f4c5fedc0b7bd5843e40",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/bioc/actions/runs/29989524003"
    },
    {
      "r": "4.6.1",
      "os": "mac",
      "version": "1.25.0",
      "date": "2026-07-23T07:58:20.000Z",
      "commit": "d2fa1dc894d94d3498a26a1f8c7bf0875d1f22ee",
      "fileid": "https://r2.ropensci.org/a7203f5c948e9d266cc965e7ea0d85455ac5009736247b68c8d00435765e2be1",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/bioc/actions/runs/29989524003"
    },
    {
      "r": "4.6.0",
      "os": "wasm",
      "version": "1.25.0",
      "date": "2026-07-23T07:58:59.000Z",
      "commit": "d2fa1dc894d94d3498a26a1f8c7bf0875d1f22ee",
      "fileid": "https://r2.ropensci.org/e602aba40fd9917e7e67676713c372543fa6aba78cdb396ca7879e9111aa4d6d",
      "status": "success",
      "buildurl": "https://github.com/r-universe/bioc/actions/runs/29989524003"
    },
    {
      "r": "4.7.0",
      "os": "win",
      "version": "1.25.0",
      "date": "2026-07-23T07:58:18.000Z",
      "commit": "d2fa1dc894d94d3498a26a1f8c7bf0875d1f22ee",
      "fileid": "https://r2.ropensci.org/1a8d8db3f1235bb31a639f038042c8ea0f494a1ca586475c4cab046a28b65b6c",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/bioc/actions/runs/29989524003"
    },
    {
      "r": "4.5.3",
      "os": "win",
      "version": "1.25.0",
      "date": "2026-07-23T07:59:05.000Z",
      "commit": "d2fa1dc894d94d3498a26a1f8c7bf0875d1f22ee",
      "fileid": "https://r2.ropensci.org/3188505d49dcdd31709471896c6bfe0069a39abde8d3d306ae62fc9da22761db",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/bioc/actions/runs/29989524003"
    },
    {
      "r": "4.6.1",
      "os": "win",
      "version": "1.25.0",
      "date": "2026-07-23T07:58:36.000Z",
      "commit": "d2fa1dc894d94d3498a26a1f8c7bf0875d1f22ee",
      "fileid": "https://r2.ropensci.org/64331282362176a1dbca2f2841df182d4b77362ebd52c192ba7a57c11debd785",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/bioc/actions/runs/29989524003"
    }
  ]
}