{
  "_id": "6a103acfacfb0bcc41c9b4a7",
  "Package": "rexposome",
  "Version": "1.35.0",
  "Title": "Exposome exploration and outcome data analysis",
  "Authors@R": "c(person(\"Carles\", \"Hernandez-Ferrer\", , \"carles.hernandez@isglobal.org\", c(\"aut\", \"cre\")),\nperson(\"Juan R.\", \"Gonzalez\", ,\"juanr.gonzalez@isglobal.org\", role = \"aut\"),\nperson(\"Xavier\", \"Escribà-Montagut\", ,\"xavier.escriba@isglobal.org\", role = \"aut\"))",
  "Maintainer": "Xavier Escribà Montagut <xavier.escriba@isglobal.org>",
  "Description": "Package that allows to explore the exposome and to perform\nassociation analyses between exposures and health outcomes.",
  "License": "MIT + file LICENSE",
  "Encoding": "UTF-8",
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  "biocViews": "Software, BiologicalQuestion, Infrastructure, DataImport,\nDataRepresentation, BiomedicalInformatics, ExperimentalDesign,\nMultipleComparison, Classification, Clustering",
  "Config/pak/sysreqs": "cmake make libicu-dev libuv1-dev libx11-dev\nzlib1g-dev",
  "Repository": "https://bioc.r-universe.dev",
  "Date/Publication": "2026-05-11 17:35:33 UTC",
  "RemoteUrl": "https://github.com/bioc/rexposome",
  "RemoteRef": "HEAD",
  "RemoteSha": "2a65b5f87612f67d196aae2a521620654e05ab0a",
  "NeedsCompilation": "no",
  "Packaged": {
    "Date": "2026-05-11 22:09:20 UTC",
    "User": "root"
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  "Author": "Carles Hernandez-Ferrer [aut, cre],\nJuan R. Gonzalez [aut],\nXavier Escribà-Montagut [aut]",
  "MD5sum": "57a2ae6b17c9e070b1c47fc1225f62d7",
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  "_created": "2026-05-11T22:09:20.000Z",
  "_published": "2026-05-22T11:15:27.320Z",
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  "_exports": [
    "classification",
    "clustering",
    "correlation",
    "expos",
    "exposureNames",
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    "exwas",
    "familyNames",
    "get_robust_sd",
    "highAndLow",
    "ilod",
    "imputation",
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    "invExWAS",
    "loadExposome",
    "loadExposome_plain",
    "loadImputed",
    "mexwas",
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    "normalityTest",
    "pca",
    "phenotypeNames",
    "plot3PCA",
    "plotClassification",
    "plotCorrelation",
    "plotEffect",
    "plotEXP",
    "plotExwas",
    "plotFamily",
    "plotHistogram",
    "plotLOD",
    "plotMissings",
    "plotPCA",
    "plotPHE",
    "plotVolcano",
    "readExposome",
    "standardize",
    "tableLOD",
    "tableMissings",
    "tef",
    "toES",
    "trans",
    "volcano_plot"
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    {
      "name": "ex_imp",
      "title": "'imExposomeSet' for testing purpouses",
      "object": "ex_imp",
      "class": [
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      "fields": [],
      "table": false,
      "tojson": false
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      "name": "expo",
      "title": "'ExposomeSet' for testing purpouses",
      "object": "exposome",
      "class": [
        "ExposomeSet"
      ],
      "fields": [],
      "table": false,
      "tojson": false
    },
    {
      "name": "expo_c",
      "title": "'ExposomeClust' for testing purpouses",
      "object": "eclust",
      "class": [
        "ExposomeClust"
      ],
      "fields": [],
      "table": false,
      "tojson": false
    },
    {
      "name": "me",
      "title": "'data.frame' for testing purpouses",
      "object": "me",
      "class": [
        "data.frame"
      ],
      "fields": [
        ".imp",
        ".id",
        "DDE",
        "DDT",
        "HCB",
        "bHCH",
        "PCB118",
        "PCB153",
        "PCB180",
        "PCB138",
        "BPA",
        "THM",
        "CHCl3",
        "BTHM",
        "Cotinine",
        "Gas",
        "ETS",
        "H_pesticides",
        "G_pesticides",
        "Benzene",
        "PM25CU",
        "PM25FE",
        "PM25K",
        "PM25Ni",
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        "PM25Sl",
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        "PM25Zn",
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        "PM10Fe",
        "PM10K",
        "PM10Ni",
        "PM10S",
        "PM10SI",
        "PM10V",
        "PM10Zn",
        "NO2",
        "NO",
        "NOx",
        "PM25",
        "PM10",
        "PMcoarse",
        "AbsPM25",
        "Dens",
        "Conn",
        "Green",
        "Noise_d",
        "Noise_n",
        "Temp",
        "whistling_chest",
        "flu",
        "rhinitis",
        "wheezing",
        "sex",
        "age",
        "cbmi",
        "blood_pre"
      ],
      "rows": 654,
      "table": true,
      "tojson": true
    }
  ],
  "_help": [
    {
      "page": "classification-methods",
      "title": "Method to get the classification of the samples from an ExposomeClust.",
      "topics": [
        "classification"
      ]
    },
    {
      "page": "clustering-methods",
      "title": "Method to perform clustering on the samples of an ExposomeSet",
      "topics": [
        "clustering"
      ]
    },
    {
      "page": "correlation-methods",
      "title": "Creation of an ExposomeCorr from an ExposomeSet.",
      "topics": [
        "correlation"
      ]
    },
    {
      "page": "ex_imp",
      "title": "'imExposomeSet' for testing purpouses",
      "topics": [
        "ex_imp"
      ]
    },
    {
      "page": "expo",
      "title": "'ExposomeSet' for testing purpouses",
      "topics": [
        "expo"
      ]
    },
    {
      "page": "expo_c",
      "title": "'ExposomeClust' for testing purpouses",
      "topics": [
        "expo_c"
      ]
    },
    {
      "page": "expos-methods",
      "title": "Returns the exposures matrix of an ExposomeSet.",
      "topics": [
        "expos"
      ]
    },
    {
      "page": "ExposomeClust-class",
      "title": "Class ExposomeClust",
      "topics": [
        "classification,ExposomeClust-method",
        "ExposomeClust",
        "ExposomeClust-class",
        "plot,ExposomeClust,ANY-method",
        "plotClassification,ExposomeClust-method",
        "sampleNames,ExposomeClust-method"
      ]
    },
    {
      "page": "ExposomeCorr-class",
      "title": "Class ExposomeCorr",
      "topics": [
        "dim,ExposomeCorr-method",
        "ExposomeCorr",
        "ExposomeCorr-class",
        "extract,ExposomeCorr-method",
        "plot,ExposomeCorr,ANY-method",
        "plotCorrelation,ExposomeCorr-method"
      ]
    },
    {
      "page": "ExposomePCA-class",
      "title": "Class ExposomePCA",
      "topics": [
        "ExposomePCA",
        "ExposomePCA-class",
        "exposureNames,ExposomePCA-method",
        "extract,ExposomePCA-method",
        "ndim,ExposomePCA-method",
        "phenotypeNames,ExposomePCA-method",
        "plot,ExposomePCA,ANY-method",
        "plot3PCA,ExposomePCA-method",
        "plotEXP,ExposomePCA-method",
        "plotPCA,ExposomePCA-method",
        "plotPHE,ExposomePCA-method"
      ]
    },
    {
      "page": "ExposomeSet-class",
      "title": "Class ExposomeSet",
      "topics": [
        "clustering,ExposomeSet-method",
        "correlation,ExposomeSet-method",
        "dim,ExposomeSet-method",
        "expos,ExposomeSet-method",
        "ExposomeSet",
        "ExposomeSet-class",
        "exposureNames,ExposomeSet-method",
        "exwas,ExposomeSet-method",
        "familyNames,ExposomeSet-method",
        "highAndLow,ExposomeSet-method",
        "ilod,ExposomeSet-method",
        "imputation,ExposomeSet-method",
        "invExWAS,ExposomeSet-method",
        "mexwas,ExposomeSet-method",
        "normalityTest,ExposomeSet-method",
        "pca,ExposomeSet-method",
        "phenotypeNames,ExposomeSet-method",
        "plot,ExposomeSet,ANY-method",
        "plotFamily,ExposomeSet-method",
        "plotHistogram,ExposomeSet-method",
        "plotLOD,ExposomeSet-method",
        "plotMissings,ExposomeSet-method",
        "standardize,ExposomeSet-method",
        "Summary,ExposomeSet-method",
        "tableLOD,ExposomeSet-method",
        "tableMissings,ExposomeSet-method",
        "trans,ExposomeSet-method"
      ]
    },
    {
      "page": "exposureNames-methods",
      "title": "Getter to obtain the exposures's names of an ExposomeSet or ExposomePCA",
      "topics": [
        "exposureNames"
      ]
    },
    {
      "page": "extract-methods",
      "title": "Raw data from 'ExWAS', 'ExposomeClust' and 'ExposomeCorr'.",
      "topics": [
        "extract"
      ]
    },
    {
      "page": "exwas-methods",
      "title": "Testing the association between an exposure and a phenotype of an ExposomeSet",
      "topics": [
        "exwas"
      ]
    },
    {
      "page": "ExWAS-class",
      "title": "Class ExWAS",
      "topics": [
        "extract,ExWAS-method",
        "ExWAS",
        "ExWAS-class",
        "get_robust_sd,ExWAS-method",
        "names,ExWAS-method",
        "plot,ExWAS,ANY-method",
        "plotEffect,ExWAS-method",
        "plotExwas,ExWAS-method",
        "plotVolcano,ExWAS-method",
        "tef,ExWAS-method"
      ]
    },
    {
      "page": "familyNames-methods",
      "title": "Getter to obtain the exposures's names of an ExposomeSet.",
      "topics": [
        "familyNames"
      ]
    },
    {
      "page": "get_robust_sd-methods",
      "title": "Raw data from 'ExWAS'",
      "topics": [
        "extract",
        "get_robust_sd"
      ]
    },
    {
      "page": "highAndLow-methods",
      "title": "Function to convert continuous exposures to categorical exposures",
      "topics": [
        "highAndLow"
      ]
    },
    {
      "page": "ilod-methods",
      "title": "Function to impute under-LOD values from an ExposomeSet",
      "topics": [
        "ilod"
      ]
    },
    {
      "page": "imExposomeSet-class",
      "title": "Class imExposomeSet",
      "topics": [
        "dim,imExposomeSet-method",
        "expos,imExposomeSet-method",
        "exposureNames,imExposomeSet-method",
        "extract,imExposomeSet-method",
        "exwas,imExposomeSet-method",
        "familyNames,imExposomeSet-method",
        "imExposomeSet",
        "imExposomeSet-class",
        "imExposomeSet-methods",
        "phenotypeNames,imExposomeSet-method",
        "plot,imExposomeSet,ANY-method",
        "plotFamily,imExposomeSet-method",
        "sampleNames,imExposomeSet-method",
        "toES,imExposomeSet-method",
        "[",
        "[,imExposomeSet,ANY,ANY,ANY-method",
        "[[,imExposomeSet-method"
      ]
    },
    {
      "page": "imputation-methods",
      "title": "Function to impute missing values from an ExposomeSet",
      "topics": [
        "imputation"
      ]
    },
    {
      "page": "imputeLOD",
      "title": "Function to impute values under limit of detection",
      "topics": [
        "imputeLOD"
      ]
    },
    {
      "page": "invExWAS-methods",
      "title": "Testing the association between an exposure and a phenotype of an ExposomeSet (modelling the exposures as response)",
      "topics": [
        "invExWAS"
      ]
    },
    {
      "page": "loadExposome",
      "title": "Creation of an ExposomeSet from 'data.frames'",
      "topics": [
        "loadExposome"
      ]
    },
    {
      "page": "loadExposome_plain",
      "title": "Creation of an ExposomeSet from single 'data.frame'",
      "topics": [
        "loadExposome_plain"
      ]
    },
    {
      "page": "loadImputed",
      "title": "Creation of an imExposomeSet from 'data.frames'",
      "topics": [
        "loadImputed"
      ]
    },
    {
      "page": "me",
      "title": "'data.frame' for testing purpouses",
      "topics": [
        "me"
      ]
    },
    {
      "page": "mexwas-methods",
      "title": "Testing the association between an exposure and a phenotype of an ExposomeSet using a multivariate aproach.",
      "topics": [
        "mexwas"
      ]
    },
    {
      "page": "mExWAS-class",
      "title": "Class mExWAS",
      "topics": [
        "extract,mExWAS-method",
        "mExWAS",
        "mExWAS-class",
        "plot,mExWAS,ANY-method",
        "plotExwas,mExWAS-method"
      ]
    },
    {
      "page": "ndim-methods",
      "title": "Number of principal components in an ExposomePCA.",
      "topics": [
        "ndim"
      ]
    },
    {
      "page": "normalityTest-methods",
      "title": "It creates a 'data.frame' of boolean indicating if the exposures follows a normal distribution or not.",
      "topics": [
        "normalityTest"
      ]
    },
    {
      "page": "pca-methods",
      "title": "Creation of an ExposomePCA from an ExposomeSet.",
      "topics": [
        "pca"
      ]
    },
    {
      "page": "phenotypeNames-methods",
      "title": "Getter to obtain the phenotype's names of an ExposomeSet or ExposomePCA.",
      "topics": [
        "phenotypeNames"
      ]
    },
    {
      "page": "plot3PCA-methods",
      "title": "Ploting PCA in a 3D space",
      "topics": [
        "plot3PCA"
      ]
    },
    {
      "page": "plotClassification-methods",
      "title": "Draw the profile of the levels exposures after a classification with a clustering method",
      "topics": [
        "plotClassification"
      ]
    },
    {
      "page": "plotCorrelation-methods",
      "title": "It draws both circos or matrix plot for the correlation in ExposomeCorr",
      "topics": [
        "plotCorrelation"
      ]
    },
    {
      "page": "plotEffect-methods",
      "title": "Function to draw a plot of the pvalues stored in an 'ExWAS' object",
      "topics": [
        "plotEffect"
      ]
    },
    {
      "page": "plotEXP-methods",
      "title": "Plot correlation between exposures and PCA",
      "topics": [
        "plotEXP"
      ]
    },
    {
      "page": "plotExwas-methods",
      "title": "Function to draw a plot of the pvalues stored in an 'ExWAS' object",
      "topics": [
        "plotExwas"
      ]
    },
    {
      "page": "plotFamily-methods",
      "title": "It draws the profile of the exposome in an ExposomeSet",
      "topics": [
        "plotFamily"
      ]
    },
    {
      "page": "plotHistogram-methods",
      "title": "It draws a histogram for each exposure in an ExposomeSet",
      "topics": [
        "plotHistogram"
      ]
    },
    {
      "page": "plotLOD-methods",
      "title": "It draws a chart with the percentage of under-LOD values in an ExposomeSet",
      "topics": [
        "plotLOD"
      ]
    },
    {
      "page": "plotMissings-methods",
      "title": "It draws a chart with the percentage of missing in an ExposomeSet",
      "topics": [
        "plotMissings"
      ]
    },
    {
      "page": "plotPCA-methods",
      "title": "Ploting PCA",
      "topics": [
        "plotPCA"
      ]
    },
    {
      "page": "plotPHE-methods",
      "title": "Plot association score between phentoypes and PCA",
      "topics": [
        "plotPHE"
      ]
    },
    {
      "page": "plotVolcano-methods",
      "title": "Function to draw a plot of the pvalues stored in an 'ExWAS' object",
      "topics": [
        "plotVolcano"
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    {
      "page": "readExposome",
      "title": "Creation of an ExposomeSet from files",
      "topics": [
        "readExposome"
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    },
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      "page": "rexposome",
      "title": "rexposome: Package for exposome exploration and outcome data analysis",
      "topics": [
        "rexposome"
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    {
      "page": "standardize-methods",
      "title": "#' Summary of an ExposomeSet. #' #' Given an ExposomeSet is shows a summary for its exposures or #' its phenotypes. #' #' @name Summary #' @rdname Summary-methods #' @aliases Summary #' @param object codeExposomeSet with 'set' will be summarized. #' @param set Set to be sumarized ('\"exposures\"' or '\"phenotypes\"'). #' @param select Subseting of exposures of phenotypes. #' @return A basic description of the exposures in the 'ExposomeSet' #' @examples #' data(\"exposome\") #' Summary(expo, set = \"exposures\") #' @export Summary setGeneric(\"Summary\", function(object, set=c(\"exposures\", \"phenotypes\"), select) standardGeneric(\"Summary\") ) Standardize of an ExposomeSet.",
      "topics": [
        "standardize"
      ]
    },
    {
      "page": "tableLOD-methods",
      "title": "It creates a vector with the amount of under-LOD exposures in an ExposomeSet",
      "topics": [
        "tableLOD"
      ]
    },
    {
      "page": "tableMissings-methods",
      "title": "It creates a vector with the amount of missing in an ExposomeSet",
      "topics": [
        "tableMissings"
      ]
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    {
      "page": "tef-methods",
      "title": "Function to get the Threshold for effective tests (TEF)",
      "topics": [
        "tef"
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      "page": "toES",
      "title": "Method to convert an imExposomeSet to an ExposomeSet",
      "topics": [
        "toES"
      ]
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    {
      "page": "trans-methods",
      "title": "Function to apply a transformation to the exposures of an ExposomeSet",
      "topics": [
        "trans"
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    },
    {
      "page": "volcano_plot",
      "title": "Function to draw a Volcano Plot",
      "topics": [
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      "title": "Dealing with Multiple Imputations",
      "author": "Carles Hernandez-Ferrer and Juan R. Gonzalez",
      "engine": "knitr::rmarkdown",
      "headings": [
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