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  "Title": "rcellminer: Molecular Profiles, Drug Response, and Chemical\nStructures for the NCI-60 Cell Lines",
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  "Date": "2025-04-11",
  "Author": "Augustin Luna, Vinodh Rajapakse, Fabricio Sousa",
  "Maintainer": "Augustin Luna <augustin.luna@nih.gov>, Vinodh Rajapakse\n<vinodh.rajapakse@nih.gov>, Fathi Elloumi\n<fathi.elloumi@nih.gov>",
  "Description": "The NCI-60 cancer cell line panel has been used over the\ncourse of several decades as an anti-cancer drug screen. This\npanel was developed as part of the Developmental Therapeutics\nProgram (DTP, http://dtp.nci.nih.gov/) of the U.S. National\nCancer Institute (NCI). Thousands of compounds have been tested\non the NCI-60, which have been extensively characterized by\nmany platforms for gene and protein expression, copy number,\nmutation, and others (Reinhold, et al., 2012). The purpose of\nthe CellMiner project (http://discover.nci.nih.gov/ cellminer)\nhas been to integrate data from multiple platforms used to\nanalyze the NCI-60 and to provide a powerful suite of tools for\nexploration of NCI-60 data.",
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      "concept": [
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      "concept": [
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      "concept": [
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      "title": "Returns a list of data frames with feature information.",
      "concept": [
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      "topics": [
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      "title": "Returns a list of data frames with feature information.",
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      "title": "Returns a list of data frames with feature information.",
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      "page": "getMedSenLineActivity",
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      "concept": [
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      "concept": [
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      "title": "Get MOA string",
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      "concept": [
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      "concept": [
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      "title": "Returns a vector indicating the number of NCI-60 cell lines with missing activity data for set of compounds.",
      "concept": [
        "rcellminer"
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      "topics": [
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      "title": "Returns an eSet object with drug repeat activity experiment data.",
      "concept": [
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      "title": "Returns an eSet object with drug repeat activity experiment data.",
      "concept": [
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      "topics": [
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      "title": "Computes the relative standard deviation values with respect to the columns of a matrix or data.frame.",
      "concept": [
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    },
    {
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      "concept": [
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      "page": "getSampleData-DrugData-method",
      "title": "Returns a data frame with sample information.",
      "concept": [
        "rcellminerData"
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      "topics": [
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    },
    {
      "page": "getSampleData-MolData-method",
      "title": "Returns a data frame with sample information.",
      "concept": [
        "rcellminerData"
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      "topics": [
        "getSampleData,MolData-method"
      ]
    },
    {
      "page": "getSmiles",
      "title": "Get the SMILES strings for a set of NSC identifiers.",
      "concept": [
        "rcellminer"
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      "topics": [
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    },
    {
      "page": "hasMoa",
      "title": "Check if NSC has Mechanism of Action (MOA) Annotation",
      "concept": [
        "rcellminer"
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    },
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      "title": "Returns a DrugData object.",
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      "title": "Returns a MolData object.",
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      "concept": [
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      "title": "Using rcellminer",
      "engine": "knitr::rmarkdown",
      "headings": [
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        "Installation",
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        "Searching for Compounds",
        "Profile Visualization",
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