{
  "_id": "6a1af5131d7bb097a09f9184",
  "Package": "phenoTest",
  "Type": "Package",
  "Title": "Tools to test association between gene expression and phenotype\nin a way that is efficient, structured, fast and scalable. We\nalso provide tools to do GSEA (Gene set enrichment analysis)\nand copy number variation.",
  "Version": "1.61.0",
  "Date": "2013-05-29",
  "Author": "Evarist Planet",
  "Maintainer": "Evarist Planet <evarist.planet@epfl.ch>",
  "Description": "Tools to test correlation between gene expression and\nphenotype in a way that is efficient, structured, fast and\nscalable. GSEA is also provided.",
  "License": "GPL (>=2)",
  "LazyLoad": "yes",
  "biocViews": "Microarray, DifferentialExpression, MultipleComparison,\nClustering, Classification",
  "Config/pak/sysreqs": "cmake make libicu-dev libpng-dev libuv1-dev\nlibxml2-dev libssl-dev zlib1g-dev",
  "Repository": "https://bioc.r-universe.dev",
  "Date/Publication": "2026-04-28 12:35:04 UTC",
  "RemoteUrl": "https://github.com/bioc/phenoTest",
  "RemoteRef": "HEAD",
  "RemoteSha": "9c9fc2085ae2eca2f73d41eee70b5511fb4b8829",
  "NeedsCompilation": "no",
  "Packaged": {
    "Date": "2026-05-30 09:45:50 UTC",
    "User": "root"
  },
  "MD5sum": "be9e8a84690d4e46b16a3a620127cb54",
  "_user": "bioc",
  "_type": "src",
  "_file": "phenoTest_1.61.0.tar.gz",
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  "_filesize": 1377555,
  "_sha256": "7962384289da45d190cc1e258ab1f3093446f2549a7760e1bf3ac1ed3fddb1d2",
  "_created": "2026-05-30T09:45:50.000Z",
  "_published": "2026-05-30T14:32:51.623Z",
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    "warning": 5,
    "note": 17
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  "_buildurl": "https://github.com/r-universe/bioc/actions/runs/26676629181",
  "_status": "success",
  "_host": "GitHub-Actions",
  "_upstream": "https://github.com/bioc/phenoTest",
  "_commit": {
    "id": "9c9fc2085ae2eca2f73d41eee70b5511fb4b8829",
    "author": "A Wokaty <andres.wokaty@sph.cuny.edu>",
    "committer": "A Wokaty <andres.wokaty@sph.cuny.edu>",
    "message": "bump x.y.z version to odd y following creation of RELEASE_3_23 branch\n",
    "time": 1777379704
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  "_maintainer": {
    "name": "Evarist Planet",
    "email": "evarist.planet@epfl.ch",
    "login": "evaristplanet",
    "description": "",
    "uuid": 6883969
  },
  "_distro": "noble",
  "_registered": true,
  "_dependencies": [
    {
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      "version": ">= 3.6.0",
      "role": "Depends"
    },
    {
      "package": "Biobase",
      "role": "Depends"
    },
    {
      "package": "methods",
      "role": "Depends"
    },
    {
      "package": "annotate",
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    {
      "package": "Heatplus",
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    {
      "package": "BMA",
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    {
      "package": "ggplot2",
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    },
    {
      "package": "Hmisc",
      "role": "Depends"
    },
    {
      "package": "survival",
      "role": "Imports"
    },
    {
      "package": "limma",
      "role": "Imports"
    },
    {
      "package": "gplots",
      "role": "Imports"
    },
    {
      "package": "Category",
      "role": "Imports"
    },
    {
      "package": "AnnotationDbi",
      "role": "Imports"
    },
    {
      "package": "hopach",
      "role": "Imports"
    },
    {
      "package": "biomaRt",
      "role": "Imports"
    },
    {
      "package": "GSEABase",
      "role": "Imports"
    },
    {
      "package": "genefilter",
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    },
    {
      "package": "xtable",
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      "package": "annotate",
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    {
      "package": "mgcv",
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    {
      "package": "hgu133a.db",
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    },
    {
      "package": "ellipse",
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  "_selfowned": true,
  "_usedby": 1,
  "_updates": [
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      "week": "2025-44",
      "n": 2
    },
    {
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  ],
  "_tags": [],
  "_bioc": [
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      "branch": "devel",
      "version": "1.61.0",
      "bioc": "3.24"
    },
    {
      "branch": "release",
      "version": "1.60.0",
      "bioc": "3.23"
    }
  ],
  "_topics": [
    "microarray",
    "differentialexpression",
    "multiplecomparison",
    "clustering",
    "classification"
  ],
  "_userbio": {
    "uuid": 2286807,
    "type": "organization",
    "name": "Bioconductor",
    "description": "Software for the analysis and comprehension of high-throughput genomic data"
  },
  "_downloads": {
    "count": 534,
    "source": "https://www.bioconductor.org/packages/stats/bioc/phenoTest"
  },
  "_mentions": 6,
  "_searchresults": 26,
  "_rbuild": "4.6.0",
  "_assets": [
    "extra/citation.cff",
    "extra/citation.html",
    "extra/citation.json",
    "extra/citation.txt",
    "extra/contents.json",
    "extra/phenoTest.html",
    "manual.pdf"
  ],
  "_realowner": "bioc",
  "_cranurl": false,
  "_exports": [
    "approach",
    "barplotSignatures",
    "barplotSignifSignatures",
    "ClusterPhenoTest",
    "epheno2html",
    "eset2genelevel",
    "export2CSV",
    "ExpressionPhenoTest",
    "findCopyNumber",
    "genesInArea",
    "getEs",
    "getEsPositions",
    "getEsSim",
    "getFc",
    "getFcHr",
    "getHr",
    "getMeans",
    "getPostProbs",
    "getPvals",
    "getSignif",
    "getSummaryDif",
    "getVars2test",
    "gsea",
    "gsea.selGsets",
    "gsea.selVars",
    "gsea2html",
    "gseaSignatures",
    "gseaSignificance",
    "heatmapPhenoTest",
    "logFcHr",
    "p.adjust.method",
    "pAdjust",
    "pca",
    "phenoClass",
    "phenoNames",
    "plot.gseaData",
    "plot.gseaSignaturesSign",
    "plot.gseaSignaturesVar",
    "show",
    "smoothCoxph",
    "summary.gseaData",
    "summary.gseaSignificanceSign",
    "summary.gseaSignificanceVar",
    "write.html"
  ],
  "_datasets": [
    {
      "name": "epheno",
      "title": "epheno object.",
      "object": "epheno",
      "file": "epheno.RData",
      "class": [
        "epheno"
      ],
      "fields": [],
      "table": false,
      "tojson": false
    },
    {
      "name": "eset",
      "title": "Example data.",
      "object": "eset",
      "file": "eset.genelevel.RData",
      "class": [
        "ExpressionSet"
      ],
      "fields": [],
      "table": false,
      "tojson": false
    },
    {
      "name": "eset.genelevel",
      "title": "Example data.",
      "object": "eset.genelevel",
      "file": "eset.genelevel.RData",
      "class": [
        "ExpressionSet"
      ],
      "fields": [],
      "table": false,
      "tojson": false
    }
  ],
  "_help": [
    {
      "page": "phenoTest-package",
      "title": "Test correlation between gene expression and phenotype.",
      "topics": [
        "phenoTest-package",
        "phenoTest"
      ]
    },
    {
      "page": "plots4epheno",
      "title": "Summary plots for gene signature vs phenotype association",
      "topics": [
        "barplotSignatures",
        "barplotSignifSignatures"
      ]
    },
    {
      "page": "barplotSignatures-methods",
      "title": "Methods for Function barplotSignatures in Package `phenoTest'",
      "topics": [
        "barplotSignatures,epheno,character-method",
        "barplotSignatures,epheno,GeneSet-method",
        "barplotSignatures,epheno,GeneSetCollection-method",
        "barplotSignatures,epheno,list-method",
        "barplotSignatures-methods"
      ]
    },
    {
      "page": "barplotSignifSignatures-methods",
      "title": "Methods for Function barplotSignifSignatures in Package `phenoTest'",
      "topics": [
        "barplotSignifSignatures,epheno,character-method",
        "barplotSignifSignatures,epheno,GeneSet-method",
        "barplotSignifSignatures,epheno,GeneSetCollection-method",
        "barplotSignifSignatures,epheno,list-method",
        "barplotSignifSignatures-methods"
      ]
    },
    {
      "page": "ClusterPhenoTest",
      "title": "Test association of clusters with phenotype.",
      "topics": [
        "ClusterPhenoTest"
      ]
    },
    {
      "page": "epheno",
      "title": "epheno object.",
      "topics": [
        "epheno"
      ]
    },
    {
      "page": "epheno-class",
      "title": "Class \"epheno\"",
      "topics": [
        "approach,epheno-method",
        "dim,epheno-method",
        "epheno-class",
        "getFc,epheno-method",
        "getHr,epheno-method",
        "getMeans,epheno-method",
        "getPostProbs,epheno-method",
        "getPvals,epheno-method",
        "getSignif,epheno-method",
        "getSummaryDif,epheno-method",
        "logFcHr,epheno-method",
        "p.adjust.method,epheno-method",
        "phenoClass,epheno-method",
        "phenoNames,epheno-method",
        "show,epheno-method",
        "[,epheno,ANY,ANY-method"
      ]
    },
    {
      "page": "epheno2html",
      "title": "Create html files and plots from an epheno object.",
      "topics": [
        "epheno2html"
      ]
    },
    {
      "page": "eset",
      "title": "Example data.",
      "topics": [
        "eset"
      ]
    },
    {
      "page": "eset.genelevel",
      "title": "Example data.",
      "topics": [
        "eset.genelevel"
      ]
    },
    {
      "page": "eset2genelevel",
      "title": "Filter ExpressionSet to keep one probeset per gene.",
      "topics": [
        "eset2genelevel"
      ]
    },
    {
      "page": "export2CSV",
      "title": "Export object to comma-separated text file.",
      "topics": [
        "export2CSV"
      ]
    },
    {
      "page": "export2CSV-methods",
      "title": "Methods for Function export2CSV in Package 'phenoTest'",
      "topics": [
        "export2CSV,epheno-method",
        "export2CSV-methods"
      ]
    },
    {
      "page": "ExpressionPhenoTest",
      "title": "Tests univariate association between a list of phenotype variables and gene expression.",
      "topics": [
        "ExpressionPhenoTest"
      ]
    },
    {
      "page": "findCopyNumber",
      "title": "Find copy number regions using expression data in a similar way ACE does.",
      "topics": [
        "findCopyNumber"
      ]
    },
    {
      "page": "genesInArea",
      "title": "Find genes that are in given areas.",
      "topics": [
        "genesInArea"
      ]
    },
    {
      "page": "getGseaSignatures",
      "title": "Substract element's of a gseaSignaturesSign or gseaSignaturesVar object (obtained using the gseaSignatures function).",
      "topics": [
        "getEs",
        "getEsSim",
        "getFcHr",
        "getNes"
      ]
    },
    {
      "page": "getEsPositions",
      "title": "Obtain chromosome positions for each gene.",
      "topics": [
        "getEsPositions"
      ]
    },
    {
      "page": "ephenoGetters",
      "title": "Getters for the epheno object:",
      "topics": [
        "approach",
        "getFc",
        "getHr",
        "getMeans",
        "getPostProbs",
        "getPvals",
        "getSignif",
        "getSummaryDif",
        "logFcHr",
        "p.adjust.method",
        "phenoClass",
        "phenoNames",
        "[,epheno,ANY,ANY,ANY-method"
      ]
    },
    {
      "page": "getVars2test",
      "title": "Get phenotypic variables that were tested.",
      "topics": [
        "getVars2test"
      ]
    },
    {
      "page": "getVars2test-methods",
      "title": "Methods for Function getVars2test in Package `phenoTest'",
      "topics": [
        "getVars2test,epheno-method",
        "getVars2test-methods"
      ]
    },
    {
      "page": "gsea",
      "title": "GSEA (Gene Set Enrichment Analysis).",
      "topics": [
        "gsea"
      ]
    },
    {
      "page": "gsea.subset",
      "title": "Subset an object of class gseaData.",
      "topics": [
        "gsea.selGsets",
        "gsea.selVars"
      ]
    },
    {
      "page": "gsea2html",
      "title": "Export an object of class gseaData to an html file.",
      "topics": [
        "gsea2html"
      ]
    },
    {
      "page": "gseaData-class",
      "title": "Class \"gseaData\"",
      "topics": [
        "getEs,gseaData-method",
        "getEsSim,gseaData-method",
        "getFcHr,gseaData-method",
        "gseaData-class",
        "show,gseaData-method"
      ]
    },
    {
      "page": "gseaSignatures",
      "title": "Compute ES (enrichment scores) and es.sim (simulated enrichment scores) for given phenotipic variable(s) and signature(s).",
      "topics": [
        "gseaSignatures"
      ]
    },
    {
      "page": "gseaSignatures-class",
      "title": "Class \"gseaSignatures\" ES and EsSim container.",
      "topics": [
        "gseaSignatures-class"
      ]
    },
    {
      "page": "gseaSignatures-methods",
      "title": "Methods for Function gseaSignatures in Package `phenoTest'",
      "topics": [
        "gseaSignatures,ANY,character-method",
        "gseaSignatures,ANY,GeneSet-method",
        "gseaSignatures,epheno,GeneSetCollection-method",
        "gseaSignatures,epheno,list-method",
        "gseaSignatures,matrix,GeneSetCollection-method",
        "gseaSignatures,matrix,list-method",
        "gseaSignatures,numeric,GeneSetCollection-method",
        "gseaSignatures,numeric,list-method",
        "gseaSignatures-methods"
      ]
    },
    {
      "page": "gseaSignaturesSign-class",
      "title": "Class \"gseaSignaturesSign\"",
      "topics": [
        "getEs,gseaSignaturesSign-method",
        "getEsSim,gseaSignaturesSign-method",
        "getFcHr,gseaSignaturesSign-method",
        "gseaSignaturesSign-class",
        "gseaSignificance,gseaSignaturesSign-method"
      ]
    },
    {
      "page": "gseaSignaturesVar-class",
      "title": "Class \"gseaSignaturesVar\"",
      "topics": [
        "getEs,gseaSignaturesVar-method",
        "getEsSim,gseaSignaturesVar-method",
        "getFcHr,gseaSignaturesVar-method",
        "gseaSignaturesVar-class",
        "gseaSignificance,gseaSignaturesVar-method"
      ]
    },
    {
      "page": "gseaSignificance",
      "title": "ES' (enrichment scores) sifgnificance.",
      "topics": [
        "gseaSignificance"
      ]
    },
    {
      "page": "gseaSignificanceSign-class",
      "title": "Class \"gseaSignificanceSign\"",
      "topics": [
        "gseaSignificanceSign-class"
      ]
    },
    {
      "page": "gseaSignificanceVar-class",
      "title": "Class \"gseaSignificanceVar\"",
      "topics": [
        "gseaSignificanceVar-class"
      ]
    },
    {
      "page": "heatmapPhenoTest",
      "title": "Produce heatmap from phenotype data.",
      "topics": [
        "heatmapPhenoTest"
      ]
    },
    {
      "page": "heatmapPhenoTest-methods",
      "title": "Methods for Function heatmapPhenoTest in Package `phenoTest'",
      "topics": [
        "heatmapPhenoTest,ExpressionSet,character-method",
        "heatmapPhenoTest,ExpressionSet,GeneSet-method",
        "heatmapPhenoTest,ExpressionSet,GeneSetCollection-method",
        "heatmapPhenoTest,ExpressionSet,list-method",
        "heatmapPhenoTest,ExpressionSet,missing-method",
        "heatmapPhenoTest-methods"
      ]
    },
    {
      "page": "pAdjust",
      "title": "Adjust p values of an epheno object.",
      "topics": [
        "pAdjust"
      ]
    },
    {
      "page": "pAdjust-methods",
      "title": "Methods for Function pAdjust in Package `phenoTest'",
      "topics": [
        "pAdjust,epheno-method",
        "pAdjust-methods"
      ]
    },
    {
      "page": "pca",
      "title": "Principal components plot.",
      "topics": [
        "pca"
      ]
    },
    {
      "page": "plot.gsea",
      "title": "GSEA-like Plot.",
      "topics": [
        "plot.gseaData"
      ]
    },
    {
      "page": "plot.gseaSignatures",
      "title": "GSEA-like Plot.",
      "topics": [
        "plot.gseaSignaturesSign",
        "plot.gseaSignaturesVar"
      ]
    },
    {
      "page": "show-methods",
      "title": "Methods for Function show in Package `methods'.",
      "topics": [
        "show,AnnotatedDataFrame-method",
        "show,ANY-method",
        "show,classRepresentation-method",
        "show,container-method",
        "show,eSet-method",
        "show,genericFunction-method",
        "show,gseaSignaturesSign-method",
        "show,gseaSignaturesVar-method",
        "show,gseaSignificanceSign-method",
        "show,gseaSignificanceVar-method",
        "show,LargeDataObject-method",
        "show,MethodDefinition-method",
        "show,MethodSelectionReport-method",
        "show,MethodWithNext-method",
        "show,MIAME-method",
        "show,namedList-method",
        "show,ObjectsWithPackage-method",
        "show,oldClass-method",
        "show,ScalarCharacter-method",
        "show,ScalarObject-method",
        "show,signature-method",
        "show,TestResults-method",
        "show,traceable-method",
        "show,Versioned-method",
        "show,Versions-method",
        "show,VersionsNull-method",
        "show-methods"
      ]
    },
    {
      "page": "smoothCoxph",
      "title": "Plots the Cox proportional hazard smoothed by gene expression level.",
      "topics": [
        "smoothCoxph"
      ]
    },
    {
      "page": "summary.gsea",
      "title": "Obtain a data.frame with the pvalues and fdr for all signatures and variables of a gseaData object.",
      "topics": [
        "summary.gseaData"
      ]
    },
    {
      "page": "summary.gseaSignificance",
      "title": "Obtain a data.frame with the pvalues and fdr for all signatures and variables of a gseaSignificanceSign or gseaSignificanceVar object.",
      "topics": [
        "summary.gseaSignificanceSign",
        "summary.gseaSignificanceVar"
      ]
    },
    {
      "page": "write.html",
      "title": "Write a data.frame to an html file.",
      "topics": [
        "write.html"
      ]
    }
  ],
  "_rundeps": [
    "annotate",
    "AnnotationDbi",
    "askpass",
    "backports",
    "base64enc",
    "BH",
    "Biobase",
    "BiocFileCache",
    "BiocGenerics",
    "biomaRt",
    "Biostrings",
    "bit",
    "bit64",
    "bitops",
    "blob",
    "BMA",
    "bslib",
    "cachem",
    "Category",
    "caTools",
    "checkmate",
    "cli",
    "cluster",
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