{ "_id": "6a1af4261d7bb097a09f8b71", "Package": "multicrispr", "Title": "Multi-locus multi-purpose Crispr/Cas design", "Version": "1.23.0", "Encoding": "UTF-8", "Authors@R": "c(person(\"Aditya\", \"Bhagwat\", NULL, \"aditya.bhagwat@uni-marburg.de\", c(\"aut\", \"cre\")),\nperson( \"Richie\", \"´Cotton\", NULL, \"richierocks@gmail.com\", \"aut\"),\nperson( \"Rene\", \"Wiegandt\", NULL, \"rene.wiegandt@mpi-bn.mpg.de\", \"ctb\"),\nperson( \"Mette\", \"Bentsen\", NULL, \"mette.bentsen@mpi-bn.mpg.de\", \"ctb\"),\nperson( \"Jens\", \"Preussner\", NULL, \"jens.preussner@mpi-bn.mpg.de\", \"ctb\"),\nperson( \"Michael\", \"Lawrence\", NULL, \"lawrence.michael@gene.com\", \"ctb\"),\nperson( \"Hervé\", \"Pagès\", NULL, \"hpages.on.github@gmail.com\", \"ctb\"),\nperson( \"Johannes\", \"Graumann\", NULL, 'johannes.graumann@uni-marburg.de', \"sad\"),\nperson( \"Mario\", \"Looso\", NULL, \"mario.looso@mpi-bn.mpg.de\", c(\"sad\",\"rth\")))", "Description": "This package is for designing Crispr/Cas9 and Prime\nEditing experiments. It contains functions to (1) define and\ntransform genomic targets, (2) find spacers (4) count offtarget\n(mis)matches, and (5) compute Doench2016/2014 targeting\nefficiency. Care has been taken for multicrispr to scale well\ntowards large target sets, enabling the design of large\nCrispr/Cas9 libraries.", "License": "GPL-2", "RoxygenNote": "7.3.2", "VignetteBuilder": "knitr", "biocViews": "CRISPR, Software", "BugReports": "https://github.com/bhagwataditya/multicrispr/issues", "URL": "https://github.com/bhagwataditya/multicrispr", "Config/pak/sysreqs": "cmake make libbz2-dev libicu-dev liblzma-dev\nlibpng-dev libuv1-dev libxml2-dev libssl-dev python3 libx11-dev\nxz-utils zlib1g-dev", "Repository": "https://bioc.r-universe.dev", "Date/Publication": "2026-04-28 12:52:55 UTC", "RemoteUrl": "https://github.com/bioc/multicrispr", "RemoteRef": "HEAD", "RemoteSha": "aabd0f0ef3227f26fb58496d6f18c7f8480b0cf4", "NeedsCompilation": "no", "Packaged": { "Date": "2026-05-30 09:44:37 UTC", "User": "root" }, "Author": "Aditya Bhagwat [aut, cre],\nRichie ´Cotton [aut],\nRene Wiegandt [ctb],\nMette Bentsen [ctb],\nJens Preussner [ctb],\nMichael Lawrence [ctb],\nHervé Pagès 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