{
  "_id": "6a4973ecf408bf5a1e5fde7d",
  "Package": "metapod",
  "Version": "1.21.0",
  "Date": "2026-02-18",
  "Title": "Meta-Analyses on P-Values of Differential Analyses",
  "Authors@R": "person(\"Aaron\", \"Lun\", role=c(\"aut\", \"cre\"), email = \"infinite.monkeys.with.keyboards@gmail.com\")",
  "biocViews": "MultipleComparison, DifferentialPeakCalling",
  "Description": "Implements a variety of methods for combining p-values in\ndifferential analyses of genome-scale datasets. Functions can\ncombine p-values across different tests in the same analysis\n(e.g., genomic windows in ChIP-seq, exons in RNA-seq) or for\ncorresponding tests across separate analyses (e.g., replicated\ncomparisons, effect of different treatment conditions). Support\nis provided for handling log-transformed input p-values,\nmissing values and weighting where appropriate.",
  "License": "GPL-3",
  "URL": "https://github.com/LTLA/metapod",
  "BugReports": "https://github.com/LTLA/metapod/issues",
  "NeedsCompilation": "yes",
  "SystemRequirements": "C++11",
  "VignetteBuilder": "knitr",
  "RoxygenNote": "7.3.3",
  "Encoding": "UTF-8",
  "Repository": "https://bioc.r-universe.dev",
  "Date/Publication": "2026-04-28 12:54:31 UTC",
  "RemoteUrl": "https://github.com/bioc/metapod",
  "RemoteRef": "HEAD",
  "RemoteSha": "b1a66ff48329c4e0e6df918ca4bd9f0fa40755af",
  "Packaged": {
    "Date": "2026-06-23 15:09:13 UTC",
    "User": "root"
  },
  "Author": "Aaron Lun [aut, cre]",
  "Maintainer": "Aaron Lun <infinite.monkeys.with.keyboards@gmail.com>",
  "_user": "bioc",
  "_type": "src",
  "_file": "metapod_1.21.0.tar.gz",
  "_fileid": "https://r2.ropensci.org/270fbd1382eed4d33aceee98a91f157d807903d1a3efc48335db7ee9e3e44b3d",
  "_filesize": 229095,
  "_sha256": "270fbd1382eed4d33aceee98a91f157d807903d1a3efc48335db7ee9e3e44b3d",
  "_expires": "2026-10-12T20:58:19.000Z",
  "_created": "2026-06-23T15:09:13.000Z",
  "_published": "2026-07-04T20:58:20.905Z",
  "_bioccheck": {
    "error": 0,
    "warning": 1,
    "note": 4
  },
  "_host": "GitHub-Actions",
  "_buildurl": "https://github.com/r-universe/bioc/actions/runs/28035653097",
  "_status": "success",
  "_upstream": "https://github.com/bioc/metapod",
  "_commit": {
    "id": "b1a66ff48329c4e0e6df918ca4bd9f0fa40755af",
    "author": "A Wokaty <andres.wokaty@sph.cuny.edu>",
    "committer": "A Wokaty <andres.wokaty@sph.cuny.edu>",
    "message": "bump x.y.z version to odd y following creation of RELEASE_3_23 branch\n",
    "time": 1777380871
  },
  "_maintainer": {
    "name": "Aaron Lun",
    "email": "infinite.monkeys.with.keyboards@gmail.com",
    "login": "ltla",
    "twitter": "@realAaronLun",
    "description": "(ノಠ益ಠ)ノ彡┻━┻\n",
    "uuid": 8166669
  },
  "_distro": "resolute",
  "_jobs": [
    {
      "job": 85166449570,
      "time": 161,
      "config": "bioc-checks",
      "r": "4.6.0",
      "check": "WARNING",
      "artifact": "7825012260"
    },
    {
      "job": 85166449590,
      "time": 184,
      "config": "linux-devel-arm64",
      "r": "4.7.0",
      "check": "NOTE",
      "artifact": "7825024674"
    },
    {
      "job": 85166449529,
      "time": 188,
      "config": "linux-devel-x86_64",
      "r": "4.7.0",
      "check": "NOTE",
      "artifact": "7825024278"
    },
    {
      "job": 85166449596,
      "time": 146,
      "config": "linux-release-arm64",
      "r": "4.6.0",
      "check": "NOTE",
      "artifact": "7825007380"
    },
    {
      "job": 85166449536,
      "time": 196,
      "config": "linux-release-x86_64",
      "r": "4.6.0",
      "check": "NOTE",
      "artifact": "7825026676"
    },
    {
      "job": 85166449591,
      "time": 147,
      "config": "macos-oldrel-arm64",
      "r": "4.5.3",
      "check": "NOTE",
      "artifact": "7825005823"
    },
    {
      "job": 85166449564,
      "time": 296,
      "config": "macos-oldrel-x86_64",
      "r": "4.5.3",
      "check": "NOTE",
      "artifact": "7825068944"
    },
    {
      "job": 85166449618,
      "time": 135,
      "config": "macos-release-arm64",
      "r": "4.6.0",
      "check": "NOTE",
      "artifact": "7825000819"
    },
    {
      "job": 85166449431,
      "time": 291,
      "config": "macos-release-x86_64",
      "r": "4.6.0",
      "check": "NOTE",
      "artifact": "7825067791"
    },
    {
      "job": 85166449419,
      "time": 210,
      "config": "source",
      "r": "4.6.0",
      "check": "OK",
      "artifact": "7824941880"
    },
    {
      "job": 85166449416,
      "time": 122,
      "config": "wasm-release",
      "r": "4.6.0",
      "check": "OK",
      "artifact": "7824995938"
    },
    {
      "job": 85166449512,
      "time": 166,
      "config": "windows-devel",
      "r": "4.7.0",
      "check": "NOTE",
      "artifact": "7825014441"
    },
    {
      "job": 85166449483,
      "time": 143,
      "config": "windows-oldrel",
      "r": "4.5.3",
      "check": "NOTE",
      "artifact": "7825004472"
    },
    {
      "job": 85166449520,
      "time": 142,
      "config": "windows-release",
      "r": "4.6.0",
      "check": "NOTE",
      "artifact": "7825004057"
    }
  ],
  "_registered": true,
  "_dependencies": [
    {
      "package": "Rcpp",
      "role": "LinkingTo"
    },
    {
      "package": "Rcpp",
      "role": "Imports"
    },
    {
      "package": "testthat",
      "role": "Suggests"
    },
    {
      "package": "knitr",
      "role": "Suggests"
    },
    {
      "package": "BiocStyle",
      "role": "Suggests"
    },
    {
      "package": "rmarkdown",
      "role": "Suggests"
    }
  ],
  "_owner": "bioc",
  "_selfowned": true,
  "_usedby": 54,
  "_updates": [
    {
      "week": "2025-44",
      "n": 2
    },
    {
      "week": "2025-47",
      "n": 2
    },
    {
      "week": "2026-08",
      "n": 1
    },
    {
      "week": "2026-18",
      "n": 2
    }
  ],
  "_tags": [],
  "_bioc": [
    {
      "branch": "devel",
      "version": "1.21.0",
      "bioc": "3.24"
    },
    {
      "branch": "release",
      "version": "1.20.0",
      "bioc": "3.23"
    }
  ],
  "_topics": [
    "multiplecomparison",
    "differentialpeakcalling",
    "cpp"
  ],
  "_stars": 2,
  "_contributors": [
    {
      "user": "ltla",
      "count": 58,
      "uuid": 8166669
    },
    {
      "user": "jwokaty",
      "count": 14,
      "uuid": 1744257
    },
    {
      "user": "nturaga",
      "count": 6,
      "uuid": 2746443
    }
  ],
  "_userbio": {
    "uuid": 2286807,
    "type": "organization",
    "name": "Bioconductor",
    "followers": 441,
    "description": "Software for the analysis and comprehension of high-throughput genomic data"
  },
  "_devurl": "https://github.com/ltla/metapod",
  "_searchresults": 20,
  "_rbuild": "4.6.0",
  "_assets": [
    "extra/citation.cff",
    "extra/citation.html",
    "extra/citation.json",
    "extra/citation.txt",
    "extra/contents.json",
    "extra/metapod.html",
    "extra/NEWS.html",
    "extra/NEWS.txt",
    "extra/readme.html",
    "extra/readme.md",
    "manual.pdf"
  ],
  "_homeurl": "https://github.com/ltla/metapod",
  "_realowner": "bioc",
  "_cranurl": false,
  "_exports": [
    "averageGroupedStats",
    "averageParallelStats",
    "combineGroupedPValues",
    "combineParallelPValues",
    "countGroupedDirection",
    "countParallelDirection",
    "groupedBerger",
    "groupedFisher",
    "groupedHolmMin",
    "groupedPearson",
    "groupedSimes",
    "groupedStouffer",
    "groupedWilkinson",
    "parallelBerger",
    "parallelFisher",
    "parallelHolmMin",
    "parallelPearson",
    "parallelSimes",
    "parallelStouffer",
    "parallelWilkinson",
    "summarizeGroupedDirection",
    "summarizeParallelDirection"
  ],
  "_help": [
    {
      "page": "metapod-package",
      "title": "metapod: Meta-Analyses on P-Values of Differential Analyses",
      "topics": [
        "metapod-package",
        "metapod"
      ]
    },
    {
      "page": "averageGroupedStats",
      "title": "Average grouped statistics",
      "topics": [
        "averageGroupedStats"
      ]
    },
    {
      "page": "averageParallelStats",
      "title": "Average parallel statistics",
      "topics": [
        "averageParallelStats"
      ]
    },
    {
      "page": "combineGroupedPValues",
      "title": "Combine grouped p-values",
      "topics": [
        "combineGroupedPValues"
      ]
    },
    {
      "page": "combineParallelPValues",
      "title": "Combine parallel p-values",
      "topics": [
        "combineParallelPValues"
      ]
    },
    {
      "page": "countGroupedDirection",
      "title": "Count directions of grouped tests",
      "topics": [
        "countGroupedDirection"
      ]
    },
    {
      "page": "countParallelDirection",
      "title": "Count directions of parallel tests",
      "topics": [
        "countParallelDirection"
      ]
    },
    {
      "page": "groupedBerger",
      "title": "Combine grouped p-values with Berger's IUT",
      "topics": [
        "groupedBerger"
      ]
    },
    {
      "page": "groupedFisher",
      "title": "Combine grouped p-values with Fisher's method",
      "topics": [
        "groupedFisher"
      ]
    },
    {
      "page": "groupedHolmMin",
      "title": "Combine grouped p-values with the minimum Holm approach",
      "topics": [
        "groupedHolmMin"
      ]
    },
    {
      "page": "groupedPearson",
      "title": "Combine grouped p-values with Pearson's method",
      "topics": [
        "groupedPearson"
      ]
    },
    {
      "page": "groupedSimes",
      "title": "Combine grouped p-values with Simes' method",
      "topics": [
        "groupedSimes"
      ]
    },
    {
      "page": "groupedStouffer",
      "title": "Combine grouped p-values with Stouffer's Z-score method",
      "topics": [
        "groupedStouffer"
      ]
    },
    {
      "page": "groupedWilkinson",
      "title": "Combine grouped p-values with Wilkinson's method",
      "topics": [
        "groupedWilkinson"
      ]
    },
    {
      "page": "parallelBerger",
      "title": "Combine parallel p-values with Berger's IUT",
      "topics": [
        "parallelBerger"
      ]
    },
    {
      "page": "parallelFisher",
      "title": "Combine parallel p-values with Fisher's method",
      "topics": [
        "parallelFisher"
      ]
    },
    {
      "page": "parallelHolmMin",
      "title": "Combine parallel p-values with the minimum Holm approach",
      "topics": [
        "parallelHolmMin"
      ]
    },
    {
      "page": "parallelPearson",
      "title": "Combine parallel p-values with Pearson's method",
      "topics": [
        "parallelPearson"
      ]
    },
    {
      "page": "parallelSimes",
      "title": "Combine parallel p-values with Simes' method",
      "topics": [
        "parallelSimes"
      ]
    },
    {
      "page": "parallelStouffer",
      "title": "Combine parallel p-values with Stouffer's Z-score",
      "topics": [
        "parallelStouffer"
      ]
    },
    {
      "page": "parallelWilkinson",
      "title": "Combine p-values with Wilkinson's method",
      "topics": [
        "parallelWilkinson"
      ]
    },
    {
      "page": "summarizeGroupedDirection",
      "title": "Summarize overall direction of grouped tests",
      "topics": [
        "summarizeGroupedDirection"
      ]
    },
    {
      "page": "summarizeParallelDirection",
      "title": "Summarize overall direction of parallel tests",
      "topics": [
        "summarizeParallelDirection"
      ]
    }
  ],
  "_readme": "https://github.com/bioc/metapod/raw/HEAD/README.md",
  "_rundeps": [
    "Rcpp"
  ],
  "_sysdeps": [
    {
      "shlib": "libstdc++",
      "package": "libstdc++6",
      "source": "gcc",
      "version": "16-20260322-1ubuntu1",
      "name": "c++",
      "homepage": "http://gcc.gnu.org/",
      "description": "GNU Standard C++ Library v3"
    }
  ],
  "_vignettes": [
    {
      "source": "overview.Rmd",
      "filename": "overview.html",
      "title": "Meta-analyses on p-values of various differential tests",
      "author": "Aaron Lun",
      "engine": "knitr::rmarkdown",
      "headings": [
        "Overview",
        "Meta-analyses on $p$-values",
        "$p$-value combining strategies",
        "Summarizing the direction",
        "Further comments",
        "Session information"
      ],
      "created": "2020-11-02 06:27:32",
      "modified": "2021-05-12 07:09:49",
      "commits": 2
    }
  ],
  "_score": 7.413634997198556,
  "_indexed": true,
  "_nocasepkg": "metapod",
  "_universes": [
    "bioc",
    "ltla"
  ],
  "_binaries": [
    {
      "r": "4.7.0",
      "os": "linux",
      "version": "1.21.0",
      "date": "2026-06-23T15:12:26.000Z",
      "distro": "resolute",
      "arch": "aarch64",
      "commit": "b1a66ff48329c4e0e6df918ca4bd9f0fa40755af",
      "fileid": "https://r2.ropensci.org/f165dc89364118fe005e7adb886329ceaef22346a366357d76bf2b5024b4fb8c",
      "status": "success",
      "check": "NOTE",
      "buildurl": "https://github.com/r-universe/bioc/actions/runs/28035653097"
    },
    {
      "r": "4.7.0",
      "os": "linux",
      "version": "1.21.0",
      "date": "2026-06-23T15:12:21.000Z",
      "distro": "resolute",
      "arch": "x86_64",
      "commit": "b1a66ff48329c4e0e6df918ca4bd9f0fa40755af",
      "fileid": "https://r2.ropensci.org/e7c545ddc4e41b5a6e57d61980b928ff73082b32774caff19172cd259ad0952f",
      "status": "success",
      "check": "NOTE",
      "buildurl": "https://github.com/r-universe/bioc/actions/runs/28035653097"
    },
    {
      "r": "4.6.0",
      "os": "linux",
      "version": "1.21.0",
      "date": "2026-06-23T15:11:48.000Z",
      "distro": "resolute",
      "arch": "aarch64",
      "commit": "b1a66ff48329c4e0e6df918ca4bd9f0fa40755af",
      "fileid": "https://r2.ropensci.org/a3e4ec4274774a522edd643c522e9a33b4262540e301189a5bbc7fbd01b4f067",
      "status": "success",
      "check": "NOTE",
      "buildurl": "https://github.com/r-universe/bioc/actions/runs/28035653097"
    },
    {
      "r": "4.6.0",
      "os": "linux",
      "version": "1.21.0",
      "date": "2026-06-23T15:12:23.000Z",
      "distro": "resolute",
      "arch": "x86_64",
      "commit": "b1a66ff48329c4e0e6df918ca4bd9f0fa40755af",
      "fileid": "https://r2.ropensci.org/3c4f12793711bb0bcdff46cd20149ebdf8f0b5d2f6dcff47556e3f4b42c0a6ba",
      "status": "success",
      "check": "NOTE",
      "buildurl": "https://github.com/r-universe/bioc/actions/runs/28035653097"
    },
    {
      "r": "4.5.3",
      "os": "mac",
      "version": "1.21.0",
      "date": "2026-06-23T15:11:30.000Z",
      "arch": "aarch64",
      "commit": "b1a66ff48329c4e0e6df918ca4bd9f0fa40755af",
      "fileid": "https://r2.ropensci.org/7c0364d085601eaae7129a6c75d10c232553f31d386084e4c35cf65497ec70c6",
      "status": "success",
      "check": "NOTE",
      "buildurl": "https://github.com/r-universe/bioc/actions/runs/28035653097"
    },
    {
      "r": "4.5.3",
      "os": "mac",
      "version": "1.21.0",
      "date": "2026-06-23T15:13:10.000Z",
      "arch": "x86_64",
      "commit": "b1a66ff48329c4e0e6df918ca4bd9f0fa40755af",
      "fileid": "https://r2.ropensci.org/3bd73f3236c60395608727725831434ea8d7942158af48a3502d013734c613ef",
      "status": "success",
      "check": "NOTE",
      "buildurl": "https://github.com/r-universe/bioc/actions/runs/28035653097"
    },
    {
      "r": "4.6.0",
      "os": "mac",
      "version": "1.21.0",
      "date": "2026-06-23T15:11:14.000Z",
      "arch": "aarch64",
      "commit": "b1a66ff48329c4e0e6df918ca4bd9f0fa40755af",
      "fileid": "https://r2.ropensci.org/1d0ccca7bdd7c5324d88c3fdb6f7017596749ec64361394a85e724d1724dfbf8",
      "status": "success",
      "check": "NOTE",
      "buildurl": "https://github.com/r-universe/bioc/actions/runs/28035653097"
    },
    {
      "r": "4.6.0",
      "os": "mac",
      "version": "1.21.0",
      "date": "2026-06-23T15:13:08.000Z",
      "arch": "x86_64",
      "commit": "b1a66ff48329c4e0e6df918ca4bd9f0fa40755af",
      "fileid": "https://r2.ropensci.org/598caea809de350e547bf7bf2c2a822cc5cd516d954c844193763ab555ad0410",
      "status": "success",
      "check": "NOTE",
      "buildurl": "https://github.com/r-universe/bioc/actions/runs/28035653097"
    },
    {
      "r": "4.6.0",
      "os": "wasm",
      "version": "1.21.0",
      "date": "2026-06-23T15:11:33.000Z",
      "arch": "emscripten",
      "commit": "b1a66ff48329c4e0e6df918ca4bd9f0fa40755af",
      "fileid": "https://r2.ropensci.org/134e45ac1464eb4d9c2efccfd3f0055190ea9f2a93bf6779a2c1b19501c7b9eb",
      "status": "success",
      "buildurl": "https://github.com/r-universe/bioc/actions/runs/28035653097"
    },
    {
      "r": "4.7.0",
      "os": "win",
      "version": "1.21.0",
      "date": "2026-06-23T15:10:49.000Z",
      "arch": "x86_64",
      "commit": "b1a66ff48329c4e0e6df918ca4bd9f0fa40755af",
      "fileid": "https://r2.ropensci.org/26c791aa9aa809085e0c59cadf884fc378002945301959af372f409367cfd558",
      "status": "success",
      "check": "NOTE",
      "buildurl": "https://github.com/r-universe/bioc/actions/runs/28035653097"
    },
    {
      "r": "4.5.3",
      "os": "win",
      "version": "1.21.0",
      "date": "2026-06-23T15:10:56.000Z",
      "arch": "x86_64",
      "commit": "b1a66ff48329c4e0e6df918ca4bd9f0fa40755af",
      "fileid": "https://r2.ropensci.org/c28e24fe2b238ac927268af558204c96a79e4d6a569748badb9e44728cfb6cad",
      "status": "success",
      "check": "NOTE",
      "buildurl": "https://github.com/r-universe/bioc/actions/runs/28035653097"
    },
    {
      "r": "4.6.0",
      "os": "win",
      "version": "1.21.0",
      "date": "2026-06-23T15:10:44.000Z",
      "arch": "x86_64",
      "commit": "b1a66ff48329c4e0e6df918ca4bd9f0fa40755af",
      "fileid": "https://r2.ropensci.org/a4ea035bbf9ef5aec1b559af5432b82a4e707edf9d3c19f2f3d9c5a6adeb8030",
      "status": "success",
      "check": "NOTE",
      "buildurl": "https://github.com/r-universe/bioc/actions/runs/28035653097"
    }
  ]
}