{
  "_id": "6a1ac3221d7bb097a09da0cb",
  "Package": "metapod",
  "Version": "1.21.0",
  "Date": "2026-02-18",
  "Title": "Meta-Analyses on P-Values of Differential Analyses",
  "Authors@R": "person(\"Aaron\", \"Lun\", role=c(\"aut\", \"cre\"), email = \"infinite.monkeys.with.keyboards@gmail.com\")",
  "biocViews": "MultipleComparison, DifferentialPeakCalling",
  "Description": "Implements a variety of methods for combining p-values in\ndifferential analyses of genome-scale datasets. Functions can\ncombine p-values across different tests in the same analysis\n(e.g., genomic windows in ChIP-seq, exons in RNA-seq) or for\ncorresponding tests across separate analyses (e.g., replicated\ncomparisons, effect of different treatment conditions). Support\nis provided for handling log-transformed input p-values,\nmissing values and weighting where appropriate.",
  "License": "GPL-3",
  "URL": "https://github.com/LTLA/metapod",
  "BugReports": "https://github.com/LTLA/metapod/issues",
  "NeedsCompilation": "yes",
  "SystemRequirements": "C++11",
  "VignetteBuilder": "knitr",
  "RoxygenNote": "7.3.3",
  "Encoding": "UTF-8",
  "Repository": "https://bioc.r-universe.dev",
  "Date/Publication": "2026-04-28 12:54:31 UTC",
  "RemoteUrl": "https://github.com/bioc/metapod",
  "RemoteRef": "HEAD",
  "RemoteSha": "b1a66ff48329c4e0e6df918ca4bd9f0fa40755af",
  "Packaged": {
    "Date": "2026-05-30 07:40:09 UTC",
    "User": "root"
  },
  "Author": "Aaron Lun [aut, cre]",
  "Maintainer": "Aaron Lun <infinite.monkeys.with.keyboards@gmail.com>",
  "MD5sum": "8243730078546712e69e0b8cc2a44c7b",
  "_user": "bioc",
  "_type": "src",
  "_file": "metapod_1.21.0.tar.gz",
  "_fileid": "434817ca912855aaadb02792d56703bfccf3a6a5ca082575de29ec297ca9dcb4",
  "_filesize": 227188,
  "_sha256": "434817ca912855aaadb02792d56703bfccf3a6a5ca082575de29ec297ca9dcb4",
  "_created": "2026-05-30T07:40:09.000Z",
  "_published": "2026-05-30T10:59:46.963Z",
  "_jobs": [
    {
      "job": 78634169998,
      "time": 149,
      "config": "bioc-checks",
      "r": "4.6.0",
      "check": "WARNING",
      "artifact": "7306562010"
    },
    {
      "job": 78634170031,
      "time": 179,
      "config": "linux-devel-arm64",
      "r": "4.7.0",
      "check": "NOTE",
      "artifact": "7306564793"
    },
    {
      "job": 78634170029,
      "time": 250,
      "config": "linux-devel-x86_64",
      "r": "4.7.0",
      "check": "NOTE",
      "artifact": "7306572153"
    },
    {
      "job": 78634170049,
      "time": 143,
      "config": "linux-release-arm64",
      "r": "4.6.0",
      "check": "NOTE",
      "artifact": "7306561441"
    },
    {
      "job": 78634170037,
      "time": 197,
      "config": "linux-release-x86_64",
      "r": "4.6.0",
      "check": "NOTE",
      "artifact": "7306566690"
    },
    {
      "job": 78634170045,
      "time": 143,
      "config": "macos-oldrel-arm64",
      "r": "4.5.3",
      "check": "NOTE",
      "artifact": "7307679005"
    },
    {
      "job": 78634170038,
      "time": 275,
      "config": "macos-oldrel-x86_64",
      "r": "4.5.3",
      "check": "NOTE",
      "artifact": "7306592638"
    },
    {
      "job": 78634170034,
      "time": 127,
      "config": "macos-release-arm64",
      "r": "4.6.0",
      "check": "NOTE",
      "artifact": "7307676898"
    },
    {
      "job": 78634170039,
      "time": 217,
      "config": "macos-release-x86_64",
      "r": "4.6.0",
      "check": "NOTE",
      "artifact": "7306587514"
    },
    {
      "job": 78633995682,
      "time": 204,
      "config": "source",
      "r": "4.6.0",
      "check": "OK",
      "artifact": "7306546821"
    },
    {
      "job": 78634170000,
      "time": 111,
      "config": "wasm-release",
      "r": "4.6.0",
      "check": "OK",
      "artifact": "7306558290"
    },
    {
      "job": 78634170033,
      "time": 113,
      "config": "windows-devel",
      "r": "4.7.0",
      "check": "NOTE",
      "artifact": "7306558469"
    },
    {
      "job": 78634170019,
      "time": 108,
      "config": "windows-oldrel",
      "r": "4.5.3",
      "check": "NOTE",
      "artifact": "7306557956"
    },
    {
      "job": 78634170016,
      "time": 139,
      "config": "windows-release",
      "r": "4.6.0",
      "check": "NOTE",
      "artifact": "7306560945"
    }
  ],
  "_bioccheck": {
    "error": 0,
    "warning": 1,
    "note": 5
  },
  "_buildurl": "https://github.com/r-universe/bioc/actions/runs/26678246416",
  "_status": "success",
  "_host": "GitHub-Actions",
  "_upstream": "https://github.com/bioc/metapod",
  "_commit": {
    "id": "b1a66ff48329c4e0e6df918ca4bd9f0fa40755af",
    "author": "A Wokaty <andres.wokaty@sph.cuny.edu>",
    "committer": "A Wokaty <andres.wokaty@sph.cuny.edu>",
    "message": "bump x.y.z version to odd y following creation of RELEASE_3_23 branch\n",
    "time": 1777380871
  },
  "_maintainer": {
    "name": "Aaron Lun",
    "email": "infinite.monkeys.with.keyboards@gmail.com",
    "login": "ltla",
    "twitter": "@realAaronLun",
    "description": "(ノಠ益ಠ)ノ彡┻━┻\n",
    "uuid": 8166669
  },
  "_distro": "noble",
  "_registered": true,
  "_dependencies": [
    {
      "package": "Rcpp",
      "role": "LinkingTo"
    },
    {
      "package": "Rcpp",
      "role": "Imports"
    },
    {
      "package": "testthat",
      "role": "Suggests"
    },
    {
      "package": "knitr",
      "role": "Suggests"
    },
    {
      "package": "BiocStyle",
      "role": "Suggests"
    },
    {
      "package": "rmarkdown",
      "role": "Suggests"
    }
  ],
  "_owner": "bioc",
  "_selfowned": true,
  "_usedby": 55,
  "_updates": [
    {
      "week": "2025-44",
      "n": 2
    },
    {
      "week": "2025-47",
      "n": 2
    },
    {
      "week": "2026-08",
      "n": 1
    },
    {
      "week": "2026-18",
      "n": 2
    }
  ],
  "_tags": [],
  "_bioc": [
    {
      "branch": "devel",
      "version": "1.21.0",
      "bioc": "3.24"
    },
    {
      "branch": "release",
      "version": "1.20.0",
      "bioc": "3.23"
    }
  ],
  "_topics": [
    "multiplecomparison",
    "differentialpeakcalling",
    "cpp"
  ],
  "_stars": 2,
  "_contributors": [
    {
      "user": "ltla",
      "count": 58,
      "uuid": 8166669
    },
    {
      "user": "jwokaty",
      "count": 14,
      "uuid": 1744257
    },
    {
      "user": "nturaga",
      "count": 6,
      "uuid": 2746443
    }
  ],
  "_userbio": {
    "uuid": 2286807,
    "type": "organization",
    "name": "Bioconductor",
    "description": "Software for the analysis and comprehension of high-throughput genomic data"
  },
  "_downloads": {
    "count": 9166,
    "source": "https://www.bioconductor.org/packages/stats/bioc/metapod"
  },
  "_devurl": "https://github.com/ltla/metapod",
  "_searchresults": 20,
  "_rbuild": "4.6.0",
  "_assets": [
    "extra/citation.cff",
    "extra/citation.html",
    "extra/citation.json",
    "extra/citation.txt",
    "extra/contents.json",
    "extra/metapod.html",
    "extra/NEWS.html",
    "extra/NEWS.txt",
    "extra/readme.html",
    "extra/readme.md",
    "manual.pdf"
  ],
  "_homeurl": "https://github.com/ltla/metapod",
  "_realowner": "bioc",
  "_cranurl": false,
  "_exports": [
    "averageGroupedStats",
    "averageParallelStats",
    "combineGroupedPValues",
    "combineParallelPValues",
    "countGroupedDirection",
    "countParallelDirection",
    "groupedBerger",
    "groupedFisher",
    "groupedHolmMin",
    "groupedPearson",
    "groupedSimes",
    "groupedStouffer",
    "groupedWilkinson",
    "parallelBerger",
    "parallelFisher",
    "parallelHolmMin",
    "parallelPearson",
    "parallelSimes",
    "parallelStouffer",
    "parallelWilkinson",
    "summarizeGroupedDirection",
    "summarizeParallelDirection"
  ],
  "_help": [
    {
      "page": "metapod-package",
      "title": "metapod: Meta-Analyses on P-Values of Differential Analyses",
      "topics": [
        "metapod-package",
        "metapod"
      ]
    },
    {
      "page": "averageGroupedStats",
      "title": "Average grouped statistics",
      "topics": [
        "averageGroupedStats"
      ]
    },
    {
      "page": "averageParallelStats",
      "title": "Average parallel statistics",
      "topics": [
        "averageParallelStats"
      ]
    },
    {
      "page": "combineGroupedPValues",
      "title": "Combine grouped p-values",
      "topics": [
        "combineGroupedPValues"
      ]
    },
    {
      "page": "combineParallelPValues",
      "title": "Combine parallel p-values",
      "topics": [
        "combineParallelPValues"
      ]
    },
    {
      "page": "countGroupedDirection",
      "title": "Count directions of grouped tests",
      "topics": [
        "countGroupedDirection"
      ]
    },
    {
      "page": "countParallelDirection",
      "title": "Count directions of parallel tests",
      "topics": [
        "countParallelDirection"
      ]
    },
    {
      "page": "groupedBerger",
      "title": "Combine grouped p-values with Berger's IUT",
      "topics": [
        "groupedBerger"
      ]
    },
    {
      "page": "groupedFisher",
      "title": "Combine grouped p-values with Fisher's method",
      "topics": [
        "groupedFisher"
      ]
    },
    {
      "page": "groupedHolmMin",
      "title": "Combine grouped p-values with the minimum Holm approach",
      "topics": [
        "groupedHolmMin"
      ]
    },
    {
      "page": "groupedPearson",
      "title": "Combine grouped p-values with Pearson's method",
      "topics": [
        "groupedPearson"
      ]
    },
    {
      "page": "groupedSimes",
      "title": "Combine grouped p-values with Simes' method",
      "topics": [
        "groupedSimes"
      ]
    },
    {
      "page": "groupedStouffer",
      "title": "Combine grouped p-values with Stouffer's Z-score method",
      "topics": [
        "groupedStouffer"
      ]
    },
    {
      "page": "groupedWilkinson",
      "title": "Combine grouped p-values with Wilkinson's method",
      "topics": [
        "groupedWilkinson"
      ]
    },
    {
      "page": "parallelBerger",
      "title": "Combine parallel p-values with Berger's IUT",
      "topics": [
        "parallelBerger"
      ]
    },
    {
      "page": "parallelFisher",
      "title": "Combine parallel p-values with Fisher's method",
      "topics": [
        "parallelFisher"
      ]
    },
    {
      "page": "parallelHolmMin",
      "title": "Combine parallel p-values with the minimum Holm approach",
      "topics": [
        "parallelHolmMin"
      ]
    },
    {
      "page": "parallelPearson",
      "title": "Combine parallel p-values with Pearson's method",
      "topics": [
        "parallelPearson"
      ]
    },
    {
      "page": "parallelSimes",
      "title": "Combine parallel p-values with Simes' method",
      "topics": [
        "parallelSimes"
      ]
    },
    {
      "page": "parallelStouffer",
      "title": "Combine parallel p-values with Stouffer's Z-score",
      "topics": [
        "parallelStouffer"
      ]
    },
    {
      "page": "parallelWilkinson",
      "title": "Combine p-values with Wilkinson's method",
      "topics": [
        "parallelWilkinson"
      ]
    },
    {
      "page": "summarizeGroupedDirection",
      "title": "Summarize overall direction of grouped tests",
      "topics": [
        "summarizeGroupedDirection"
      ]
    },
    {
      "page": "summarizeParallelDirection",
      "title": "Summarize overall direction of parallel tests",
      "topics": [
        "summarizeParallelDirection"
      ]
    }
  ],
  "_readme": "https://github.com/bioc/metapod/raw/HEAD/README.md",
  "_rundeps": [
    "Rcpp"
  ],
  "_sysdeps": [
    {
      "shlib": "libstdc++",
      "package": "libstdc++6",
      "source": "gcc",
      "version": "14.2.0-4ubuntu2~24.04.1",
      "name": "c++",
      "homepage": "http://gcc.gnu.org/",
      "description": "GNU Standard C++ Library v3"
    }
  ],
  "_vignettes": [
    {
      "source": "overview.Rmd",
      "filename": "overview.html",
      "title": "Meta-analyses on p-values of various differential tests",
      "author": "Aaron Lun",
      "engine": "knitr::rmarkdown",
      "headings": [
        "Overview",
        "Meta-analyses on $p$-values",
        "$p$-value combining strategies",
        "Summarizing the direction",
        "Further comments",
        "Session information"
      ],
      "created": "2020-11-02 06:27:32",
      "modified": "2021-05-12 07:09:49",
      "commits": 2
    }
  ],
  "_score": 8.3837837797786,
  "_indexed": true,
  "_nocasepkg": "metapod",
  "_universes": [
    "bioc",
    "ltla"
  ],
  "_binaries": [
    {
      "r": "4.7.0",
      "os": "linux",
      "version": "1.21.0",
      "date": "2026-05-30T07:43:09.000Z",
      "distro": "noble",
      "arch": "aarch64",
      "commit": "b1a66ff48329c4e0e6df918ca4bd9f0fa40755af",
      "fileid": "589168d8783fba90131c67b3d6c25f24801d4277cf3fc6027a36f134dae68237",
      "status": "success",
      "check": "NOTE",
      "buildurl": "https://github.com/r-universe/bioc/actions/runs/26678246416"
    },
    {
      "r": "4.7.0",
      "os": "linux",
      "version": "1.21.0",
      "date": "2026-05-30T07:44:13.000Z",
      "distro": "noble",
      "arch": "x86_64",
      "commit": "b1a66ff48329c4e0e6df918ca4bd9f0fa40755af",
      "fileid": "daea6c46562bd35d08e5524c8cec6e253dfe626f1aad6d9ccf4392877ac9797d",
      "status": "success",
      "check": "NOTE",
      "buildurl": "https://github.com/r-universe/bioc/actions/runs/26678246416"
    },
    {
      "r": "4.6.0",
      "os": "linux",
      "version": "1.21.0",
      "date": "2026-05-30T07:42:35.000Z",
      "distro": "noble",
      "arch": "aarch64",
      "commit": "b1a66ff48329c4e0e6df918ca4bd9f0fa40755af",
      "fileid": "9ad916cd787bbd6f19fccdad71c870b8a062afe5b9ee36c6896b028e49da8a2c",
      "status": "success",
      "check": "NOTE",
      "buildurl": "https://github.com/r-universe/bioc/actions/runs/26678246416"
    },
    {
      "r": "4.6.0",
      "os": "linux",
      "version": "1.21.0",
      "date": "2026-05-30T07:43:24.000Z",
      "distro": "noble",
      "arch": "x86_64",
      "commit": "b1a66ff48329c4e0e6df918ca4bd9f0fa40755af",
      "fileid": "0ff01a882cb54294c567b8729fc033560b603903b1b52d1373a5fa27a479f9ef",
      "status": "success",
      "check": "NOTE",
      "buildurl": "https://github.com/r-universe/bioc/actions/runs/26678246416"
    },
    {
      "r": "4.5.3",
      "os": "mac",
      "version": "1.21.0",
      "date": "2026-05-30T10:56:30.000Z",
      "arch": "aarch64",
      "commit": "b1a66ff48329c4e0e6df918ca4bd9f0fa40755af",
      "fileid": "b8f66490f9879f45dbabd1969fa6afea35f2ba61e87d13215f0c8ad9cdf54e03",
      "status": "success",
      "check": "NOTE",
      "buildurl": "https://github.com/r-universe/bioc/actions/runs/26678246416"
    },
    {
      "r": "4.5.3",
      "os": "mac",
      "version": "1.21.0",
      "date": "2026-05-30T07:47:20.000Z",
      "arch": "x86_64",
      "commit": "b1a66ff48329c4e0e6df918ca4bd9f0fa40755af",
      "fileid": "c28996e1170bdabc74b331410d44978ee1d0e1e8d2905d989c733029c0594fb6",
      "status": "success",
      "check": "NOTE",
      "buildurl": "https://github.com/r-universe/bioc/actions/runs/26678246416"
    },
    {
      "r": "4.6.0",
      "os": "mac",
      "version": "1.21.0",
      "date": "2026-05-30T10:56:18.000Z",
      "arch": "aarch64",
      "commit": "b1a66ff48329c4e0e6df918ca4bd9f0fa40755af",
      "fileid": "47538ca790b628936d640f28795d34e95400857c5e262ec0cca05a865388239a",
      "status": "success",
      "check": "NOTE",
      "buildurl": "https://github.com/r-universe/bioc/actions/runs/26678246416"
    },
    {
      "r": "4.6.0",
      "os": "mac",
      "version": "1.21.0",
      "date": "2026-05-30T07:46:32.000Z",
      "arch": "x86_64",
      "commit": "b1a66ff48329c4e0e6df918ca4bd9f0fa40755af",
      "fileid": "0c2010fbed54dccec91b92ca523409e54ddc59b0b1e4da20c033d4b856d2c7ee",
      "status": "success",
      "check": "NOTE",
      "buildurl": "https://github.com/r-universe/bioc/actions/runs/26678246416"
    },
    {
      "r": "4.6.0",
      "os": "wasm",
      "version": "1.21.0",
      "date": "2026-05-30T07:42:19.000Z",
      "arch": "emscripten",
      "commit": "b1a66ff48329c4e0e6df918ca4bd9f0fa40755af",
      "fileid": "e185de090835ca0fa69d9f1758b97fb68091e816374cb7356ee7cedaf970145f",
      "status": "success",
      "buildurl": "https://github.com/r-universe/bioc/actions/runs/26678246416"
    },
    {
      "r": "4.7.0",
      "os": "win",
      "version": "1.21.0",
      "date": "2026-05-30T07:41:40.000Z",
      "arch": "x86_64",
      "commit": "b1a66ff48329c4e0e6df918ca4bd9f0fa40755af",
      "fileid": "dbd55f15643628666639e68657f6fde5f9c5a2c168903f50e17edaf86b12629e",
      "status": "success",
      "check": "NOTE",
      "buildurl": "https://github.com/r-universe/bioc/actions/runs/26678246416"
    },
    {
      "r": "4.5.3",
      "os": "win",
      "version": "1.21.0",
      "date": "2026-05-30T07:41:31.000Z",
      "arch": "x86_64",
      "commit": "b1a66ff48329c4e0e6df918ca4bd9f0fa40755af",
      "fileid": "c0be86c969dc8c1bb21bee673e71d6f530a0e163e3ac4e6f01ab72000f9d9944",
      "status": "success",
      "check": "NOTE",
      "buildurl": "https://github.com/r-universe/bioc/actions/runs/26678246416"
    },
    {
      "r": "4.6.0",
      "os": "win",
      "version": "1.21.0",
      "date": "2026-05-30T07:41:50.000Z",
      "arch": "x86_64",
      "commit": "b1a66ff48329c4e0e6df918ca4bd9f0fa40755af",
      "fileid": "8e429c771a6f8d2681eeb2e99869c4fa9cbdaaf6de2a029ae16b5d508b393602",
      "status": "success",
      "check": "NOTE",
      "buildurl": "https://github.com/r-universe/bioc/actions/runs/26678246416"
    }
  ]
}