{ "_id": "6a1f1b88b401979e7341f4d0", "Package": "magrene", "Title": "Motif Analysis In Gene Regulatory Networks", "Version": "1.15.0", "Date": "2022-01-21", "Authors@R": "c(\nperson(given = \"Fabrício\",\nfamily = \"Almeida-Silva\",\nrole = c(\"aut\", \"cre\"),\nemail = \"fabricio_almeidasilva@hotmail.com\",\ncomment = c(ORCID = \"0000-0002-5314-2964\")),\nperson(given = \"Yves\",\nfamily = \"Van de Peer\",\nrole = \"aut\",\ncomment = c(ORCID = \"0000-0003-4327-3730\"))\n)", "Description": "magrene allows the identification and analysis of graph\nmotifs in (duplicated) gene regulatory networks (GRNs),\nincluding lambda, V, PPI V, delta, and bifan motifs. GRNs can\nbe tested for motif enrichment by comparing motif frequencies\nto a null distribution generated from degree-preserving\nsimulated GRNs. Motif frequencies can be analyzed in the\ncontext of gene duplications to explore the impact of\nsmall-scale and whole-genome duplications on gene regulatory\nnetworks. Finally, users can calculate interaction similarity\nfor gene pairs based on the Sorensen-Dice similarity index.", "License": "GPL-3", "URL": "https://github.com/almeidasilvaf/magrene", "BugReports": "https://support.bioconductor.org/t/magrene", "biocViews": "Software, MotifDiscovery, NetworkEnrichment, SystemsBiology,\nGraphAndNetwork", "Encoding": "UTF-8", "Roxygen": "list(markdown = TRUE)", "RoxygenNote": "7.2.0", "Config/testthat/edition": "3", "VignetteBuilder": "knitr", "LazyData": "false", "Repository": "https://bioc.r-universe.dev", "Date/Publication": "2026-04-28 12:59:07 UTC", "RemoteUrl": "https://github.com/bioc/magrene", "RemoteRef": "HEAD", "RemoteSha": "b2761b420710edfe5cee2a0f1eb543ba3efc3803", "NeedsCompilation": "no", "Packaged": { "Date": "2026-05-16 09:20:39 UTC", "User": "root" }, "Author": "Fabrício Almeida-Silva [aut, cre] (ORCID:\n),\nYves Van de Peer [aut] (ORCID: )", "Maintainer": "Fabrício Almeida-Silva ", "MD5sum": "1fa9b76751b7fa5b92b5d8231faebb79", 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