{
  "_id": "6a1ae3611d7bb097a09eef5a",
  "Package": "hierinf",
  "Type": "Package",
  "Title": "Hierarchical Inference",
  "Version": "1.31.0",
  "Authors@R": "c(person(\"Claude\", \"Renaux\", role = c(\"aut\", \"cre\"), \nemail = \"renaux@stat.math.ethz.ch\"),\nperson(\"Laura\", \"Buzdugan\", role = c(\"aut\")),\nperson(\"Markus\", \"Kalisch\", role = c(\"aut\")),\nperson(\"Peter\", \"Bühlmann\", role = c(\"aut\")))",
  "Description": "Tools to perform hierarchical inference for one or\nmultiple studies / data sets based on high-dimensional\nmultivariate (generalised) linear models. A possible\napplication is to perform hierarchical inference for GWA\nstudies to find significant groups or single SNPs (if the\nsignal is strong) in a data-driven and automated procedure. The\nmethod is based on an efficient hierarchical multiple testing\ncorrection and controls the FWER. The functions can easily be\nrun in parallel.",
  "License": "GPL-3 | file LICENSE",
  "Encoding": "UTF-8",
  "LazyData": "yes",
  "biocViews": "Clustering, GenomeWideAssociation, LinkageDisequilibrium,\nRegression, SNP",
  "VignetteBuilder": "knitr",
  "RoxygenNote": "6.1.1",
  "Repository": "https://bioc.r-universe.dev",
  "Date/Publication": "2026-04-28 12:48:26 UTC",
  "RemoteUrl": "https://github.com/bioc/hierinf",
  "RemoteRef": "HEAD",
  "RemoteSha": "e9732418bc9000ad84a597b8df92c839970ed302",
  "NeedsCompilation": "no",
  "Packaged": {
    "Date": "2026-05-30 09:34:00 UTC",
    "User": "root"
  },
  "Author": "Claude Renaux [aut, cre],\nLaura Buzdugan [aut],\nMarkus Kalisch [aut],\nPeter Bühlmann [aut]",
  "Maintainer": "Claude Renaux <renaux@stat.math.ethz.ch>",
  "MD5sum": "6d9ddf85c3757685c507885a8b79347d",
  "_user": "bioc",
  "_type": "src",
  "_file": "hierinf_1.31.0.tar.gz",
  "_fileid": "93d0cb83595356a2c75075c9ac3ba9534450e6354ba3998f2e4e6ae4e478c6b6",
  "_filesize": 576513,
  "_sha256": "93d0cb83595356a2c75075c9ac3ba9534450e6354ba3998f2e4e6ae4e478c6b6",
  "_created": "2026-05-30T09:34:00.000Z",
  "_published": "2026-05-30T13:17:21.279Z",
  "_jobs": [
    {
      "job": 78639939288,
      "time": 149,
      "config": "bioc-checks",
      "r": "4.6.0",
      "check": "WARNING",
      "artifact": "7307287890"
    },
    {
      "job": 78639939302,
      "time": 375,
      "config": "linux-devel-x86_64",
      "r": "4.7.0",
      "check": "NOTE",
      "artifact": "7307310369"
    },
    {
      "job": 78639939298,
      "time": 387,
      "config": "linux-release-x86_64",
      "r": "4.6.0",
      "check": "NOTE",
      "artifact": "7307311436"
    },
    {
      "job": 78639939293,
      "time": 233,
      "config": "macos-oldrel-arm64",
      "r": "4.5.3",
      "check": "NOTE",
      "artifact": "7308453572"
    },
    {
      "job": 78639939296,
      "time": 199,
      "config": "macos-release-arm64",
      "r": "4.6.0",
      "check": "ERROR",
      "artifact": "7308453765"
    },
    {
      "job": 78639329769,
      "time": 228,
      "config": "source",
      "r": "4.6.0",
      "check": "OK",
      "artifact": "7307210583"
    },
    {
      "job": 78639939305,
      "time": 90,
      "config": "wasm-release",
      "r": "4.6.0",
      "check": "OK",
      "artifact": "7307281794"
    },
    {
      "job": 78639939303,
      "time": 329,
      "config": "windows-devel",
      "r": "4.7.0",
      "check": "ERROR",
      "artifact": "7307306205"
    },
    {
      "job": 78639939297,
      "time": 336,
      "config": "windows-oldrel",
      "r": "4.5.3",
      "check": "ERROR",
      "artifact": "7307306994"
    },
    {
      "job": 78639939301,
      "time": 369,
      "config": "windows-release",
      "r": "4.6.0",
      "check": "ERROR",
      "artifact": "7307310276"
    }
  ],
  "_bioccheck": {
    "error": 0,
    "warning": 3,
    "note": 16
  },
  "_buildurl": "https://github.com/r-universe/bioc/actions/runs/26675780286",
  "_status": "success",
  "_host": "GitHub-Actions",
  "_upstream": "https://github.com/bioc/hierinf",
  "_commit": {
    "id": "e9732418bc9000ad84a597b8df92c839970ed302",
    "author": "A Wokaty <andres.wokaty@sph.cuny.edu>",
    "committer": "A Wokaty <andres.wokaty@sph.cuny.edu>",
    "message": "bump x.y.z version to odd y following creation of RELEASE_3_23 branch\n",
    "time": 1777380506
  },
  "_maintainer": {
    "name": "Claude Renaux",
    "email": "renaux@stat.math.ethz.ch",
    "login": "crbasel",
    "description": "",
    "uuid": 40170197
  },
  "_distro": "noble",
  "_registered": true,
  "_dependencies": [
    {
      "package": "R",
      "version": ">= 3.6.0",
      "role": "Depends"
    },
    {
      "package": "fmsb",
      "role": "Imports"
    },
    {
      "package": "glmnet",
      "role": "Imports"
    },
    {
      "package": "methods",
      "role": "Imports"
    },
    {
      "package": "parallel",
      "role": "Imports"
    },
    {
      "package": "stats",
      "role": "Imports"
    },
    {
      "package": "knitr",
      "role": "Suggests"
    },
    {
      "package": "MASS",
      "role": "Suggests"
    },
    {
      "package": "testthat",
      "role": "Suggests"
    }
  ],
  "_owner": "bioc",
  "_selfowned": true,
  "_usedby": 0,
  "_updates": [
    {
      "week": "2025-44",
      "n": 2
    },
    {
      "week": "2026-18",
      "n": 2
    }
  ],
  "_tags": [],
  "_bioc": [
    {
      "branch": "devel",
      "version": "1.31.0",
      "bioc": "3.24"
    },
    {
      "branch": "release",
      "version": "1.30.0",
      "bioc": "3.23"
    }
  ],
  "_topics": [
    "clustering",
    "genomewideassociation",
    "linkagedisequilibrium",
    "regression",
    "snp"
  ],
  "_userbio": {
    "uuid": 2286807,
    "type": "organization",
    "name": "Bioconductor",
    "description": "Software for the analysis and comprehension of high-throughput genomic data"
  },
  "_downloads": {
    "count": 299,
    "source": "https://www.bioconductor.org/packages/stats/bioc/hierinf"
  },
  "_searchresults": 2,
  "_rbuild": "4.6.0",
  "_assets": [
    "extra/citation.cff",
    "extra/citation.html",
    "extra/citation.json",
    "extra/citation.txt",
    "extra/contents.json",
    "extra/hierinf.html",
    "extra/readme.html",
    "extra/readme.md",
    "manual.pdf"
  ],
  "_realowner": "bioc",
  "_cranurl": false,
  "_exports": [
    "cluster_position",
    "cluster_var",
    "compute_r2",
    "multisplit",
    "test_hierarchy",
    "test_only_hierarchy"
  ],
  "_datasets": [
    {
      "name": "simGWAS",
      "title": "Simulated GWAS data set",
      "object": "simGWAS",
      "class": [
        "list"
      ],
      "fields": [],
      "table": false,
      "tojson": true
    }
  ],
  "_help": [
    {
      "page": "cluster_position",
      "title": "Build Hierarchical Tree based on Position",
      "topics": [
        "cluster_position"
      ]
    },
    {
      "page": "cluster_var",
      "title": "Build Hierarchical Tree based on Hierarchical Clustering",
      "topics": [
        "cluster_var"
      ]
    },
    {
      "page": "compute_r2",
      "title": "Compute R squared",
      "topics": [
        "compute_r2"
      ]
    },
    {
      "page": "hierinf",
      "title": "hierinf: Hierarchical Inference",
      "topics": [
        "hierinf-package",
        "hierinf"
      ]
    },
    {
      "page": "multisplit",
      "title": "Multi-sample splitting",
      "topics": [
        "multisplit"
      ]
    },
    {
      "page": "print.hierT",
      "title": "Print Object of Class 'hierT'",
      "topics": [
        "print.hierT"
      ]
    },
    {
      "page": "simGWAS",
      "title": "Simulated GWAS data set",
      "topics": [
        "simGWAS"
      ]
    },
    {
      "page": "test_hierarchy",
      "title": "Hierarchical Testing",
      "topics": [
        "test_hierarchy"
      ]
    },
    {
      "page": "test_only_hierarchy",
      "title": "Hierarchical Testing",
      "topics": [
        "test_only_hierarchy"
      ]
    }
  ],
  "_readme": "https://github.com/bioc/hierinf/raw/HEAD/README.md",
  "_rundeps": [
    "codetools",
    "fmsb",
    "foreach",
    "glmnet",
    "iterators",
    "lattice",
    "Matrix",
    "Rcpp",
    "RcppEigen",
    "shape",
    "survival"
  ],
  "_vignettes": [
    {
      "source": "vignette-hierinf.Rnw",
      "filename": "vignette-hierinf.pdf",
      "title": "vignette-hierinf.Rnw",
      "engine": "knitr::knitr",
      "headings": [],
      "created": "2018-06-12 15:09:06",
      "modified": "2019-03-28 13:37:44",
      "commits": 5
    }
  ],
  "_score": 4,
  "_indexed": true,
  "_nocasepkg": "hierinf",
  "_universes": [
    "bioc",
    "crbasel"
  ],
  "_binaries": [
    {
      "r": "4.7.0",
      "os": "linux",
      "version": "1.31.0",
      "date": "2026-05-30T09:46:38.000Z",
      "distro": "noble",
      "commit": "e9732418bc9000ad84a597b8df92c839970ed302",
      "fileid": "1dff9bb2cdaee3f2bc6eefff835e4ea8e1cd087f6e1ffe98a0d475f02d1a9646",
      "status": "success",
      "check": "NOTE",
      "buildurl": "https://github.com/r-universe/bioc/actions/runs/26675780286"
    },
    {
      "r": "4.6.0",
      "os": "linux",
      "version": "1.31.0",
      "date": "2026-05-30T09:46:51.000Z",
      "distro": "noble",
      "commit": "e9732418bc9000ad84a597b8df92c839970ed302",
      "fileid": "fb75911311afa762b5b64037270ef606186298fd141eca007c9c5b8d6f7767f0",
      "status": "success",
      "check": "NOTE",
      "buildurl": "https://github.com/r-universe/bioc/actions/runs/26675780286"
    },
    {
      "r": "4.5.3",
      "os": "mac",
      "version": "1.31.0",
      "date": "2026-05-30T13:14:24.000Z",
      "commit": "e9732418bc9000ad84a597b8df92c839970ed302",
      "fileid": "66c7f153ac6244170090a58e8b233beca23ca45b259bad066cc8bc1033262092",
      "status": "success",
      "check": "NOTE",
      "buildurl": "https://github.com/r-universe/bioc/actions/runs/26675780286"
    },
    {
      "r": "4.6.0",
      "os": "mac",
      "version": "1.31.0",
      "date": "2026-05-30T13:14:44.000Z",
      "commit": "e9732418bc9000ad84a597b8df92c839970ed302",
      "fileid": "c74a6f3ed67cddbb2888ada907deafcca6ee666f75b911701194e5b4248d8db1",
      "status": "failure",
      "check": "ERROR",
      "buildurl": "https://github.com/r-universe/bioc/actions/runs/26675780286"
    },
    {
      "r": "4.6.0",
      "os": "wasm",
      "version": "1.31.0",
      "date": "2026-05-30T09:46:01.000Z",
      "commit": "e9732418bc9000ad84a597b8df92c839970ed302",
      "fileid": "23e419b1389a5015c9bacf61cb912dbaf8c0077b6950c9ef211d8f69947bd807",
      "status": "success",
      "buildurl": "https://github.com/r-universe/bioc/actions/runs/26675780286"
    },
    {
      "r": "4.7.0",
      "os": "win",
      "version": "1.31.0",
      "date": "2026-05-30T09:45:32.000Z",
      "commit": "e9732418bc9000ad84a597b8df92c839970ed302",
      "fileid": "592cb4148c4f4f7fb255b921090aca9efe94cf35def187396033db026d747770",
      "status": "failure",
      "check": "ERROR",
      "buildurl": "https://github.com/r-universe/bioc/actions/runs/26675780286"
    },
    {
      "r": "4.5.3",
      "os": "win",
      "version": "1.31.0",
      "date": "2026-05-30T09:45:29.000Z",
      "commit": "e9732418bc9000ad84a597b8df92c839970ed302",
      "fileid": "1c82d13467f7fdd45527ab6a41034a61dd1fc3962207c8dd90909b4820f48440",
      "status": "failure",
      "check": "ERROR",
      "buildurl": "https://github.com/r-universe/bioc/actions/runs/26675780286"
    },
    {
      "r": "4.6.0",
      "os": "win",
      "version": "1.31.0",
      "date": "2026-05-30T09:45:52.000Z",
      "commit": "e9732418bc9000ad84a597b8df92c839970ed302",
      "fileid": "ccc919a2bfd6874a8cbc61e543f4d83885d1060081fc073f67a287dd40f4a48f",
      "status": "failure",
      "check": "ERROR",
      "buildurl": "https://github.com/r-universe/bioc/actions/runs/26675780286"
    }
  ]
}