{
  "_id": "6a1acb261d7bb097a09dddb9",
  "Package": "hapFabia",
  "Title": "hapFabia: Identification of very short segments of identity by\ndescent (IBD) characterized by rare variants in large\nsequencing data",
  "Version": "1.55.0",
  "Date": "2017-03-11",
  "Author": "Sepp Hochreiter <hochreit@bioinf.jku.at>",
  "Maintainer": "Andreas Mitterecker <mitterecker@bioinf.jku.at>",
  "Description": "A package to identify very short IBD segments in large\nsequencing data by FABIA biclustering. Two haplotypes are\nidentical by descent (IBD) if they share a segment that both\ninherited from a common ancestor. Current IBD methods reliably\ndetect long IBD segments because many minor alleles in the\nsegment are concordant between the two haplotypes. However,\nmany cohort studies contain unrelated individuals which share\nonly short IBD segments. This package provides software to\nidentify short IBD segments in sequencing data. Knowledge of\nshort IBD segments are relevant for phasing of genotyping data,\nassociation studies, and for population genetics, where they\nshed light on the evolutionary history of humans. The package\nsupports VCF formats, is based on sparse matrix operations, and\nprovides visualization of haplotype clusters in different\nformats.",
  "License": "LGPL (>= 2.1)",
  "Collate": "AllClasses.R AllGenerics.R hapFabia.R\nmethods-Factorization-class.R methods-IBDsegment-class.R\nmethods-IBDsegmentList-class.R zzz.R",
  "URL": "http://www.bioinf.jku.at/software/hapFabia/hapFabia.html",
  "biocViews": "Genetics, GeneticVariability, SNP, Sequencing, Sequencing,\nVisualization, Clustering, SequenceMatching, Software",
  "Repository": "https://bioc.r-universe.dev",
  "Date/Publication": "2026-04-28 12:36:51 UTC",
  "RemoteUrl": "https://github.com/bioc/hapFabia",
  "RemoteRef": "HEAD",
  "RemoteSha": "067e34d1b2bcc746035b3ab5bbc3f9807c30f24a",
  "NeedsCompilation": "yes",
  "Packaged": {
    "Date": "2026-05-30 08:00:55 UTC",
    "User": "root"
  },
  "MD5sum": "3cd538b06081b52bcdffcae179b69808",
  "_user": "bioc",
  "_type": "src",
  "_file": "hapFabia_1.55.0.tar.gz",
  "_fileid": "c837003e9cb2ccb65c7f8b619d1b40a0523abab639b0b55737114f721efc6fae",
  "_filesize": 2001639,
  "_sha256": "c837003e9cb2ccb65c7f8b619d1b40a0523abab639b0b55737114f721efc6fae",
  "_created": "2026-05-30T08:00:55.000Z",
  "_published": "2026-05-30T11:33:58.617Z",
  "_jobs": [
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  ],
  "_bioccheck": {
    "error": 2,
    "warning": 1,
    "note": 17
  },
  "_buildurl": "https://github.com/r-universe/bioc/actions/runs/26678663588",
  "_status": "success",
  "_host": "GitHub-Actions",
  "_upstream": "https://github.com/bioc/hapFabia",
  "_commit": {
    "id": "067e34d1b2bcc746035b3ab5bbc3f9807c30f24a",
    "author": "A Wokaty <andres.wokaty@sph.cuny.edu>",
    "committer": "A Wokaty <andres.wokaty@sph.cuny.edu>",
    "message": "bump x.y.z version to odd y following creation of RELEASE_3_23 branch\n",
    "time": 1777379811
  },
  "_maintainer": {
    "name": "Andreas Mitterecker",
    "email": "mitterecker@bioinf.jku.at",
    "login": "mitteran",
    "description": "",
    "uuid": 13238420
  },
  "_distro": "noble",
  "_registered": true,
  "_dependencies": [
    {
      "package": "R",
      "version": ">= 3.6.0",
      "role": "Depends"
    },
    {
      "package": "Biobase",
      "role": "Depends"
    },
    {
      "package": "fabia",
      "version": ">= 2.3.1",
      "role": "Depends"
    },
    {
      "package": "methods",
      "role": "Imports"
    },
    {
      "package": "graphics",
      "role": "Imports"
    },
    {
      "package": "grDevices",
      "role": "Imports"
    },
    {
      "package": "stats",
      "role": "Imports"
    },
    {
      "package": "utils",
      "role": "Imports"
    }
  ],
  "_owner": "bioc",
  "_selfowned": true,
  "_usedby": 0,
  "_updates": [
    {
      "week": "2025-44",
      "n": 2
    },
    {
      "week": "2026-18",
      "n": 2
    }
  ],
  "_tags": [],
  "_bioc": [
    {
      "branch": "devel",
      "version": "1.55.0",
      "bioc": "3.24"
    },
    {
      "branch": "release",
      "version": "1.54.0",
      "bioc": "3.23"
    }
  ],
  "_topics": [
    "genetics",
    "geneticvariability",
    "snp",
    "sequencing",
    "visualization",
    "clustering",
    "sequencematching",
    "software"
  ],
  "_userbio": {
    "uuid": 2286807,
    "type": "organization",
    "name": "Bioconductor",
    "description": "Software for the analysis and comprehension of high-throughput genomic data"
  },
  "_downloads": {
    "count": 468,
    "source": "https://www.bioconductor.org/packages/stats/bioc/hapFabia"
  },
  "_searchresults": 14,
  "_rbuild": "4.6.0",
  "_assets": [
    "extra/citation.cff",
    "extra/citation.html",
    "extra/citation.json",
    "extra/citation.txt",
    "extra/contents.json",
    "extra/hapFabia.html",
    "extra/NEWS.html",
    "extra/NEWS.txt",
    "manual.pdf"
  ],
  "_realowner": "bioc",
  "_cranurl": false,
  "_exports": [
    "analyzeIBDsegments",
    "bicluster_id",
    "bicluster_id<-",
    "chromosome",
    "chromosome<-",
    "compareIBDsegmentLists",
    "coreClusterIndividuals",
    "coreClusterIndividuals<-",
    "extractIBDsegments",
    "findDenseRegions",
    "hapFabia",
    "hapFabiaVersion",
    "histL",
    "IBDsegment",
    "IBDsegmentLength",
    "IBDsegmentLength<-",
    "IBDsegmentList",
    "IBDsegmentList2excel",
    "IBDsegmentPos",
    "IBDsegmentPos<-",
    "IBDsegments",
    "IBDsegments<-",
    "ID",
    "ID<-",
    "identifyDuplicates",
    "idIndividuals",
    "idIndividuals<-",
    "individualPerTagSNV",
    "individualPerTagSNV<-",
    "individuals",
    "individuals<-",
    "iterateIntervals",
    "labelIndividuals",
    "labelIndividuals<-",
    "lengthList",
    "lengthList<-",
    "makePipelineFile",
    "matrixPlot",
    "mergeIBDsegmentLists",
    "numberIndividuals",
    "numberIndividuals<-",
    "numbertagSNVs",
    "numbertagSNVs<-",
    "platformIndividuals",
    "platformIndividuals<-",
    "plot",
    "plotIBDsegment",
    "plotL",
    "plotLarger",
    "populationIndividuals",
    "populationIndividuals<-",
    "setAnnotation",
    "setStatistics",
    "sim",
    "simulateIBDsegments",
    "simulateIBDsegmentsFabia",
    "split_sparse_matrix",
    "statistics",
    "statistics<-",
    "summary",
    "tagSNVAlleles",
    "tagSNVAlleles<-",
    "tagSNVAnno",
    "tagSNVAnno<-",
    "tagSNVChange",
    "tagSNVChange<-",
    "tagSNVFreq",
    "tagSNVFreq<-",
    "tagSNVGroupFreq",
    "tagSNVGroupFreq<-",
    "tagSNVNames",
    "tagSNVNames<-",
    "tagSNVPositions",
    "tagSNVPositions<-",
    "tagSNVs",
    "tagSNVs<-",
    "tagSNVsPerIndividual",
    "tagSNVsPerIndividual<-",
    "topLZ",
    "vcftoFABIA"
  ],
  "_datasets": [
    {
      "name": "chr1ASW1000G",
      "title": "Example genotype data in 'vcf' format",
      "object": "chr1ASW1000G",
      "file": "chr1ASW1000G.RData",
      "class": [
        "character"
      ],
      "fields": [],
      "table": false,
      "tojson": true
    },
    {
      "name": "hapRes",
      "title": "Example result of 'hapFabia'",
      "object": "hapRes",
      "file": "hapRes.RData",
      "class": [
        "list"
      ],
      "fields": [],
      "table": false,
      "tojson": false
    },
    {
      "name": "mergedIBDsegmentList",
      "title": "Example IBD segment list as a result of 'hapFabia'",
      "object": "mergedIBDsegmentList",
      "file": "mergedIBDsegmentList.RData",
      "class": [
        "IBDsegmentList"
      ],
      "fields": [],
      "table": false,
      "tojson": false
    },
    {
      "name": "res",
      "title": "Example result of 'spfabia'",
      "object": "res",
      "file": "res.RData",
      "class": [
        "Factorization"
      ],
      "fields": [],
      "table": false,
      "tojson": false
    },
    {
      "name": "simu",
      "title": "Example simulation data for 'hapFabia'",
      "object": "simu",
      "file": "simu.RData",
      "class": [
        "list"
      ],
      "fields": [],
      "table": false,
      "tojson": true
    }
  ],
  "_help": [
    {
      "page": "analyzeIBDsegments",
      "title": "Loop over extracted IBD segments to supply a descriptive statistics",
      "concept": [
        "genetics,haplotype,identity by descent,bicluster,next generation sequencing,genotype,single nucleotide polymorphism,single nucleotide variation,rare variants,rare SNPs, rare SNVs,rare IBD segments,short IBD segments"
      ],
      "topics": [
        "analyzeIBDsegments"
      ]
    },
    {
      "page": "chr1ASW1000G",
      "title": "Example genotype data in 'vcf' format",
      "topics": [
        "chr1ASW1000G"
      ]
    },
    {
      "page": "compareIBDsegmentLists",
      "title": "Hierarchical clustering of IBD segments stored in IBD segment list(s)",
      "concept": [
        "genetics,haplotype,identity by descent,bicluster,next generation sequencing,genotype,single nucleotide polymorphism,single nucleotide variation,rare variants,rare SNPs, rare SNVs,rare IBD segments,short IBD segments"
      ],
      "topics": [
        "compareIBDsegmentLists",
        "compareIBDsegmentLists,IBDsegmentList,ANY,character,ANY,ANY,numeric,numeric-method",
        "compareIBDsegmentLists,IBDsegmentList-method"
      ]
    },
    {
      "page": "extractIBDsegments",
      "title": "Extract IBD segments from a 'fabia' result",
      "concept": [
        "genetics,haplotype,identity by descent,bicluster,next generation sequencing,genotype,single nucleotide polymorphism,single nucleotide variation,rare variants,rare SNVs,rare IBD segments,short IBD segments"
      ],
      "topics": [
        "extractIBDsegments",
        "extractIBDsegments,Factorization,list,data.frame,character,matrix,numeric,numeric,numeric,numeric,numeric,numeric,numeric,numeric-method",
        "extractIBDsegments,Factorization-method"
      ]
    },
    {
      "page": "findDenseRegions",
      "title": "Find accumulations of values via histogram counts",
      "concept": [
        "genetics,haplotype,identity by descent,bicluster,next generation sequencing,genotype,single nucleotide polymorphism,single nucleotide variation,rare variants,rare SNPs, rare SNVs,rare IBD segments,short IBD segments"
      ],
      "topics": [
        "findDenseRegions"
      ]
    },
    {
      "page": "hapFabia",
      "title": "IBD segment extraction by FABIA",
      "concept": [
        "genetics,haplotype,identity by descent,bicluster,next\n\n  generation sequencing,genotype,single nucleotide polymorphism,single\n\n  nucleotide variation,rare variants,rare SNVs, rare\n\n  IBD segments,short IBD segments, IBD"
      ],
      "topics": [
        "hapFabia"
      ]
    },
    {
      "page": "hapFabiaVersion",
      "title": "Display version info for package 'hapFabia'",
      "concept": [
        "genetics,haplotype,identity by descent,bicluster,next\n\n  generation sequencing,genotype,single nucleotide polymorphism,single\n\n  nucleotide variation,rare variants,rare SNPs, rare SNVs,rare\n\n  IBD segments,short IBD segments, IBD"
      ],
      "topics": [
        "hapFabiaVersion"
      ]
    },
    {
      "page": "hapRes",
      "title": "Example result of 'hapFabia'",
      "topics": [
        "hapRes"
      ]
    },
    {
      "page": "IBDsegment-class",
      "title": "IBDsegment instances and methods",
      "concept": [
        "genetics,haplotype,identity by descent,bicluster,next generation sequencing,genotype,single nucleotide polymorphism,single nucleotide variation,rare variants,rare SNPs, rare SNVs,rare IBD segments,short IBD segments"
      ],
      "topics": [
        "bicluster_id",
        "bicluster_id,IBDsegment-method",
        "bicluster_id<-",
        "bicluster_id<-,IBDsegment,numeric-method",
        "chromosome",
        "chromosome,IBDsegment-method",
        "chromosome<-",
        "chromosome<-,IBDsegment,character-method",
        "coreClusterIndividuals",
        "coreClusterIndividuals,IBDsegment-method",
        "coreClusterIndividuals<-",
        "coreClusterIndividuals<-,IBDsegment,vector-method",
        "IBDsegment",
        "IBDsegment,ANY-method",
        "IBDsegment,IBDsegment-method",
        "IBDsegment,numeric,numeric,character,numeric,numeric,numeric,numeric,vector,vector,vector,vector,vector,vector,vector,vector,vector,vector,vector,vector,vector,vector,vector,vector-method",
        "IBDsegment-class",
        "IBDsegment-method",
        "IBDsegmentLength",
        "IBDsegmentLength,IBDsegment-method",
        "IBDsegmentLength<-",
        "IBDsegmentLength<-,IBDsegment,numeric-method",
        "IBDsegmentPos",
        "IBDsegmentPos,IBDsegment-method",
        "IBDsegmentPos<-",
        "IBDsegmentPos<-,IBDsegment,numeric-method",
        "ID",
        "ID,IBDsegment-method",
        "ID<-",
        "ID<-,IBDsegment,numeric-method",
        "idIndividuals",
        "idIndividuals,IBDsegment-method",
        "idIndividuals<-",
        "idIndividuals<-,IBDsegment,vector-method",
        "individualPerTagSNV",
        "individualPerTagSNV,IBDsegment-method",
        "individualPerTagSNV<-",
        "individualPerTagSNV<-,IBDsegment,vector-method",
        "individuals",
        "individuals,IBDsegment-method",
        "individuals<-",
        "individuals<-,IBDsegment,vector-method",
        "labelIndividuals",
        "labelIndividuals,IBDsegment-method",
        "labelIndividuals<-",
        "labelIndividuals<-,IBDsegment,vector-method",
        "numberIndividuals",
        "numberIndividuals,IBDsegment-method",
        "numberIndividuals<-",
        "numberIndividuals<-,IBDsegment,numeric-method",
        "numbertagSNVs",
        "numbertagSNVs,IBDsegment-method",
        "numbertagSNVs<-",
        "numbertagSNVs<-,IBDsegment,numeric-method",
        "platformIndividuals",
        "platformIndividuals,IBDsegment-method",
        "platformIndividuals<-",
        "platformIndividuals<-,IBDsegment,vector-method",
        "plot,IBDsegment,missing-method",
        "plot,IBDsegment-method",
        "plotLarger",
        "plotLarger,IBDsegment,character,numeric-method",
        "plotLarger,IBDsegment,missing-method",
        "plotLarger,IBDsegment-method",
        "populationIndividuals",
        "populationIndividuals,IBDsegment-method",
        "populationIndividuals<-",
        "populationIndividuals<-,IBDsegment,vector-method",
        "summary,IBDsegment-method",
        "tagSNVAlleles",
        "tagSNVAlleles,IBDsegment-method",
        "tagSNVAlleles<-",
        "tagSNVAlleles<-,IBDsegment,vector-method",
        "tagSNVAnno",
        "tagSNVAnno,IBDsegment-method",
        "tagSNVAnno<-",
        "tagSNVAnno<-,IBDsegment,vector-method",
        "tagSNVChange",
        "tagSNVChange,IBDsegment-method",
        "tagSNVChange<-",
        "tagSNVChange<-,IBDsegment,vector-method",
        "tagSNVFreq",
        "tagSNVFreq,IBDsegment-method",
        "tagSNVFreq<-",
        "tagSNVFreq<-,IBDsegment,vector-method",
        "tagSNVGroupFreq",
        "tagSNVGroupFreq,IBDsegment-method",
        "tagSNVGroupFreq<-",
        "tagSNVGroupFreq<-,IBDsegment,vector-method",
        "tagSNVNames",
        "tagSNVNames,IBDsegment-method",
        "tagSNVNames<-",
        "tagSNVNames<-,IBDsegment,vector-method",
        "tagSNVPositions",
        "tagSNVPositions,IBDsegment-method",
        "tagSNVPositions<-",
        "tagSNVPositions<-,IBDsegment,vector-method",
        "tagSNVs",
        "tagSNVs,IBDsegment-method",
        "tagSNVs<-",
        "tagSNVs<-,IBDsegment,vector-method",
        "tagSNVsPerIndividual",
        "tagSNVsPerIndividual,IBDsegment-method",
        "tagSNVsPerIndividual<-",
        "tagSNVsPerIndividual<-,IBDsegment,vector-method"
      ]
    },
    {
      "page": "IBDsegmentList-class",
      "title": "IBDsegmentList instances and methods",
      "concept": [
        "genetics,haplotype,identity by descent,bicluster,next generation sequencing,genotype,single nucleotide polymorphism,single nucleotide variation,rare variants,rare SNPs, rare SNVs,rare IBD segments,short IBD segments"
      ],
      "topics": [
        "IBDsegmentList",
        "IBDsegmentList,ANY-method",
        "IBDsegmentList,list,numeric,list-method",
        "IBDsegmentList-class",
        "IBDsegmentList-method",
        "IBDsegments",
        "IBDsegments,IBDsegmentList-method",
        "IBDsegments<-",
        "IBDsegments<-,IBDsegmentList,list-method",
        "lengthList",
        "lengthList,IBDsegmentList-method",
        "lengthList<-",
        "lengthList<-,IBDsegmentList,numeric-method",
        "plot,IBDsegmentList,missing-method",
        "plot,IBDsegmentList-method",
        "statistics",
        "statistics,IBDsegmentList-method",
        "statistics<-",
        "statistics<-,IBDsegmentList,list-method",
        "summary,IBDsegmentList-method",
        "[",
        "[,IBDsegmentList,numeric,missing-method",
        "[,IBDsegmentList-method",
        "[<-",
        "[<-,IBDsegmentList,numeric,missing,IBDsegmentList-method",
        "[<-,IBDsegmentList-method",
        "[[",
        "[[,IBDsegmentList,numeric,missing-method",
        "[[,IBDsegmentList-method",
        "[[<-",
        "[[<-,IBDsegmentList,numeric,missing,IBDsegment-method",
        "[[<-,IBDsegmentList-method"
      ]
    },
    {
      "page": "IBDsegmentList2excel",
      "title": "Store an IBD segment list in EXCEL / csv format",
      "concept": [
        "genetics,haplotype,identity by descent,bicluster,next generation sequencing,genotype,single nucleotide polymorphism,single nucleotide variation,rare variants,rare SNPs, rare SNVs,rare IBD segments,short IBD segments"
      ],
      "topics": [
        "IBDsegmentList2excel",
        "IBDsegmentList2excel,IBDsegmentList,character-method",
        "IBDsegmentList2excel,IBDsegmentList-method"
      ]
    },
    {
      "page": "identifyDuplicates",
      "title": "Identify duplicates of IBD segments",
      "concept": [
        "genetics,haplotype,identity by descent,bicluster,next generation sequencing,genotype,single nucleotide polymorphism,single nucleotide variation,rare variants,rare SNPs, rare SNVs,rare IBD segments,short IBD segments"
      ],
      "topics": [
        "identifyDuplicates"
      ]
    },
    {
      "page": "iterateIntervals",
      "title": "Loop over DNA intervals with a call of 'hapFabia'",
      "concept": [
        "genetics,haplotype,identity by descent,bicluster,next generation sequencing,genotype,single nucleotide polymorphism,single nucleotide variation,rare variants,rare SNPs, rare SNVs,rare IBD segments,short IBD segments"
      ],
      "topics": [
        "iterateIntervals"
      ]
    },
    {
      "page": "makePipelineFile",
      "title": "Generate 'pipleline.R'",
      "concept": [
        "genetics,haplotype,identity by descent,bicluster,next generation sequencing,genotype,single nucleotide polymorphism,single nucleotide variation,rare variants,rare SNPs, rare SNVs,rare IBD segments,short IBD segments"
      ],
      "topics": [
        "makePipelineFile"
      ]
    },
    {
      "page": "matrixPlot",
      "title": "Basic plot function for IBD segments",
      "concept": [
        "genetics,haplotype,identity by descent,bicluster,next generation sequencing,genotype,single nucleotide polymorphism,single nucleotide variation,rare variants,rare SNPs, rare SNVs,rare IBD segments,short IBD segments"
      ],
      "topics": [
        "matrixPlot"
      ]
    },
    {
      "page": "mergedIBDsegmentList",
      "title": "Example IBD segment list as a result of 'hapFabia'",
      "topics": [
        "mergedIBDsegmentList"
      ]
    },
    {
      "page": "mergeIBDsegmentLists",
      "title": "Merging IBD segments",
      "concept": [
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    },
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    {
      "page": "simulateIBDsegments",
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      "created": "2012-09-18 21:32:37",
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