{
  "_id": "6a106a9bacfb0bcc41caa114",
  "Package": "flowTime",
  "Title": "Annotation and analysis of biological dynamical systems using\nflow cytometry",
  "Version": "1.37.0",
  "Authors@R": "c(person(\"R. Clay\", \"Wright\", email =\n\"wright.clay@gmail.com\", role = c(\"aut\", \"cre\")),\nperson(\"Nick\", \"Bolten\", email = \"nbolten@gmail.com\", role =\nc(\"aut\")), person(\"Edith\", \"Pierre-Jerome\", email = \"\", role =\nc(\"aut\")))",
  "Description": "This package facilitates analysis of both timecourse and\nsteady state flow cytometry experiments. This package was\noriginially developed for quantifying the function of gene\nregulatory networks in yeast (strain W303) expressing\nfluorescent reporter proteins using BD Accuri C6 and SORP\ncytometers. However, the functions are for the most part\ngeneral and may be adapted for analysis of other organisms\nusing other flow cytometers. Functions in this package\nfacilitate the annotation of flow cytometry data with\nexperimental metadata, as often required for publication and\ngeneral ease-of-reuse. Functions for creating, saving and\nloading gate sets are also included. In the past, we have\ntypically generated summary statistics for each flowset for\neach timepoint and then annotated and analyzed these summary\nstatistics. This method loses a great deal of the power that\ncomes from the large amounts of individual cell data generated\nin flow cytometry, by essentially collapsing this data into a\nbulk measurement after subsetting. In addition to these summary\nfunctions, this package also contains functions to facilitate\nannotation and analysis of steady-state or time-lapse data\nutilizing all of the data collected from the thousands of\nindividual cells in each sample.",
  "License": "Artistic-2.0",
  "LazyData": "true",
  "biocViews": "FlowCytometry, TimeCourse, Visualization, DataImport,\nCellBasedAssays, ImmunoOncology",
  "VignetteBuilder": "knitr",
  "RoxygenNote": "7.2.2",
  "Config/pak/sysreqs": "libssl-dev",
  "Repository": "https://bioc.r-universe.dev",
  "Date/Publication": "2026-04-28 12:45:21 UTC",
  "RemoteUrl": "https://github.com/bioc/flowTime",
  "RemoteRef": "HEAD",
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  "NeedsCompilation": "no",
  "Packaged": {
    "Date": "2026-05-07 09:45:01 UTC",
    "User": "root"
  },
  "Author": "R. Clay Wright [aut, cre],\nNick Bolten [aut],\nEdith Pierre-Jerome [aut]",
  "Maintainer": "R. Clay Wright <wright.clay@gmail.com>",
  "MD5sum": "314282d246fe7ec018f06d5ae31b05f1",
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  "_published": "2026-05-22T14:39:23.924Z",
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    "visualization",
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    "read.plateSet",
    "saveGates",
    "steadyState",
    "summarizeFlow",
    "tidyFlow"
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      "object": "dipsingletGate",
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      "title": "A gate for the set of all haploid singlets",
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      "page": "addbs",
      "title": "Add background subtraction to a summary data frame",
      "topics": [
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      ]
    },
    {
      "page": "addnorm",
      "title": "Normalize fluorescence",
      "topics": [
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      ]
    },
    {
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      "title": "Annotate a flowSet with experimental metadata",
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    },
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      "title": "Create an annotation dataframe",
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    },
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      "topics": [
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      ]
    },
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      "title": "Get the time at which at flowFrame began collection",
      "topics": [
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      ]
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    },
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      "title": "Summary statistic columns for a flow frame",
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    },
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