{
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  "Package": "epimutacions",
  "Title": "Robust outlier identification for DNA methylation data",
  "Version": "1.17.2",
  "Authors@R": "c(person(\"Dolors\", \"Pelegri-Siso\", ,\"dolors.pelegri@isglobal.org\", role = c(\"aut\", \"cre\"),comment = c(ORCID = \"0000-0002-5993-3003\")),\nperson(\"Juan R.\", \"Gonzalez\", ,\"juanr.gonzalez@isglobal.org\", role = \"aut\", comment = c(ORCID = \"0000-0003-3267-2146\")),\nperson(\"Carlos\", \"Ruiz-Arenas\", ,\"carlos.ruiza@upf.edu\", role = \"aut\", comment = c(ORCID = \"0000-0002-6014-3498\")),\nperson(\"Carles\", \"Hernandez-Ferrer\", ,\"carles.hernandez@cnag.crg.eu\", role = \"aut\", comment = c(ORCID = \"0000-0002-8029-7160\")),\nperson(\"Leire\",family = \"Abarrategui\",role = c(\"aut\"),email = \"abarrategui.leire@gmail.com\", comment = c(ORCID = \"0000-0002-1175-038X\")))",
  "Description": "The package includes some statistical outlier detection\nmethods for epimutations detection in DNA methylation data. The\nmethods included in the package are MANOVA, Multivariate linear\nmodels, isolation forest, robust mahalanobis distance, quantile\nand beta. The methods compare a case sample with a suspected\ndisease against a reference panel (composed of healthy\nindividuals) to identify epimutations in the given case sample.\nIt also contains functions to annotate and visualize the\nidentified epimutations.",
  "biocViews": "DNAMethylation, BiologicalQuestion, Preprocessing,\nStatisticalMethod, Normalization",
  "License": "MIT + file LICENSE",
  "VignetteBuilder": "knitr",
  "Encoding": "UTF-8",
  "Roxygen": "list(markdown = TRUE)",
  "URL": "https://github.com/isglobal-brge/epimutacions",
  "BugReports": "https://github.com/isglobal-brge/epimutacions/issues",
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  "Repository": "https://bioc.r-universe.dev",
  "Date/Publication": "2026-09-10 09:28:38 UTC",
  "RemoteUrl": "https://github.com/bioc/epimutacions",
  "RemoteRef": "HEAD",
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  "Packaged": {
    "Date": "2026-10-11 15:58:41 UTC",
    "User": "root"
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  "Author": "Dolors Pelegri-Siso [aut, cre] (ORCID:\n<https://orcid.org/0000-0002-5993-3003>),\nJuan R. Gonzalez [aut] (ORCID: <https://orcid.org/0000-0003-3267-2146>),\nCarlos Ruiz-Arenas [aut] (ORCID:\n<https://orcid.org/0000-0002-6014-3498>),\nCarles Hernandez-Ferrer [aut] (ORCID:\n<https://orcid.org/0000-0002-8029-7160>),\nLeire Abarrategui [aut] (ORCID:\n<https://orcid.org/0000-0002-1175-038X>)",
  "Maintainer": "Dolors Pelegri-Siso <dolors.pelegri@isglobal.org>",
  "_user": "bioc",
  "_type": "src",
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  "_expires": "2027-01-19T16:49:24.000Z",
  "_created": "2026-10-11T15:58:41.000Z",
  "_published": "2026-10-11T16:49:26.272Z",
  "_buildurl": "https://github.com/r-universe/bioc/actions/runs/38152642027",
  "_status": "success",
  "_host": "GitHub-Actions",
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    "note": 7
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    "author": "dpelegri <43083225+dpelegri@users.noreply.github.com>",
    "committer": "dpelegri <43083225+dpelegri@users.noreply.github.com>",
    "message": "Fix CITATION encoding and minor BiocCheck notes\n\n- inst/CITATION: use bibentry() with ASCII-escaped (\\uXXXX) author names so\n  utils::readCitationFile() no longer warns about non-ASCII input without a\n  declared encoding.\n- vignette: give every code chunk a label.\n- plot_epimutations(): use vapply()/seq_len() instead of sapply()/1:n.\n",
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      "title": "Add ENSEMBL regulatory regions to epimutations",
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      "title": "Annotate the DMR resulting from epimutacions package",
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      "title": "Annotate the results of epimutations or epimutations_one_leave_out functions",
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      "page": "betas_from_bump",
      "title": "Obtains bumps beta values",
      "topics": [
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      ]
    },
    {
      "page": "betas_sd_mean",
      "title": "Computes beta values, standard deviation and mean to plot the epimutation",
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      "page": "epi_beta",
      "title": "Identifies epimutations based on a beta distribution.",
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      "title": "Identifies epimutations using Isolation Forest",
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      "page": "epi_mahdist",
      "title": "Identifies epimutations using Robust Mahalanobis distance",
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      "title": "Identifies epimutations using MANOVA",
      "topics": [
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      "page": "epi_parameters",
      "title": "Settings for parameters of 'epimutations' and 'epimutations_one_leave_out' functions",
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      "page": "epi_preprocess",
      "title": "Preprocess methylation array",
      "topics": [
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      "page": "epi_quantile",
      "title": "Identifies epimutations using quantile distribution",
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      "page": "epimutations",
      "title": "Epimutations analysis based on outlier detection methods",
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      "title": "Epimutations analysis based on outlier detection methods",
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      "title": "Candidate regions to be epimutations",
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        "IDAT files and reference panel",
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