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  "Title": "The GASSCO method for correcting for slide-dependent\ngene-specific dye bias",
  "Version": "1.73.0",
  "Date": "2 March 2016",
  "Author": "Philip Lijnzaad and Thanasis Margaritis",
  "Description": "Many two-colour hybridizations suffer from a dye bias that\nis both gene-specific and slide-specific. The former depends on\nthe content of the nucleotide used for labeling; the latter\ndepends on the labeling percentage. The slide-dependency was\nhitherto not recognized, and made addressing the artefact\nimpossible.  Given a reasonable number of dye-swapped pairs of\nhybridizations, or of same vs. same hybridizations, both the\ngene- and slide-biases can be estimated and corrected using the\nGASSCO method (Margaritis et al., Mol. Sys. Biol. 5:266 (2009),\ndoi:10.1038/msb.2009.21)",
  "Maintainer": "Philip Lijnzaad <plijnzaad@gmail.com>",
  "License": "GPL-3",
  "URL": "http://www.holstegelab.nl/publications/margaritis_lijnzaad",
  "biocViews": "Microarray, TwoChannel, QualityControl, Preprocessing",
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  "Date/Publication": "2026-04-28 12:33:49 UTC",
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        "dyebias"
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