{ "_id": "6ad13f0fd3c80a766859ba5e", "Package": "dominoSignal", "Title": "Cell Communication Analysis for Single Cell RNA Sequencing", "Version": "1.7.1", "Authors@R": "c(\nperson(\"Christopher\", \"Cherry\", role = c(\"aut\"), email = \"ccherry.6574@gmail.com\", comment = c(ORCID = \"0000-0002-5481-0055\")),\nperson(\"Jacob T\", \"Mitchell\", role = c(\"aut\"), email = \"jmitch81@jhmi.edu\", comment = c(ORCID = \"0000-0002-5370-9692\")),\nperson(\"Sushma\", \"Nagaraj\", role = c(\"aut\"), email = \"snagaraj@som.umaryland.edu\", comment = c(ORCID = \"0000-0001-5166-1309\")),\nperson(\"Kavita\", \"Krishnan\", role = c(\"aut\", \"cre\"), email = \"kkrishnan@som.umaryland.edu\", comment = c(ORCID = \"0000-0003-1345-0249\")),\nperson(\"Dmitrijs\", \"Lvovs\", role = c(\"aut\"), email = \"dlvovs@som.umaryland.edu\"),\nperson(\"Elana\", \"Fertig\", role = \"ctb\", email = \"ejfertig@som.umaryland.edu\", comment = c(ORCID = \"0000-0003-3204-342X\")),\nperson(\"Jennifer\", \"Elisseeff\", role = \"ctb\", email = \"jhe@jhu.edu\", comment = c(ORCID = \"0000-0002-5066-1996\"))\n)", "Description": "dominoSignal is a package developed to analyze cell\nsignaling through ligand-receptor-transcription factor networks\nin scRNAseq data. It takes as input information transcriptomic\ndata, requiring counts, z-scored counts, and cluster labels, as\nwell as information on transcription factor activity (such as\nfrom SCENIC) and a database of ligand and receptor pairings\n(such as from CellPhoneDB). This package creates an object\nstoring ligand-receptor-transcription factor linkages by\ncluster and provides several methods for exploring,\nsummarizing, and visualizing the analysis.", "BugReports": "https://github.com/FertigLab/dominoSignal/issues", "License": "GPL-3 | file LICENSE", "Encoding": "UTF-8", "LazyData": "false", "biocViews": "SystemsBiology, SingleCell, Transcriptomics, Network,\nSequencing", "VignetteBuilder": "knitr", "Language": "en-US", "URL": "https://FertigLab.github.io/dominoSignal/", "Config/roxygen2/version": "8.1.1", "Config/testthat/edition": "3", "Config/pak/sysreqs": "cmake libglpk-dev make libicu-dev libpng-dev\nlibxml2-dev libssl-dev perl zlib1g-dev", "Repository": "https://bioc.r-universe.dev", "Date/Publication": "2026-10-15 16:39:30 UTC", "RemoteUrl": "https://github.com/bioc/dominoSignal", "RemoteRef": "HEAD", "RemoteSha": "80f2f89695bb4a2849b0fc7b53b8fd140aa2014c", "NeedsCompilation": "no", "Packaged": { "Date": "2026-10-15 20:43:29 UTC", "User": 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