{ "_id": "6a1ad4851d7bb097a09e4319", "Package": "dominoSignal", "Title": "Cell Communication Analysis for Single Cell RNA Sequencing", "Version": "1.7.0", "Authors@R": "c(\nperson(\"Christopher\", \"Cherry\", role = c(\"aut\"), email = \"ccherry.6574@gmail.com\", comment = c(ORCID = \"0000-0002-5481-0055\")),\nperson(\"Jacob T\", \"Mitchell\", role = c(\"aut\"), email = \"jmitch81@jhmi.edu\", comment = c(ORCID = \"0000-0002-5370-9692\")),\nperson(\"Sushma\", \"Nagaraj\", role = c(\"aut\"), email = \"snagaraj@som.umaryland.edu\", comment = c(ORCID = \"0000-0001-5166-1309\")),\nperson(\"Kavita\", \"Krishnan\", role = c(\"aut\", \"cre\"), email = \"kkrishnan@som.umaryland.edu\", comment = c(ORCID = \"0000-0003-1345-0249\")),\nperson(\"Dmitrijs\", \"Lvovs\", role = c(\"aut\"), email = \"dlvovs@som.umaryland.edu\"),\nperson(\"Elana\", \"Fertig\", role = \"ctb\", email = \"ejfertig@som.umaryland.edu\", comment = c(ORCID = \"0000-0003-3204-342X\")),\nperson(\"Jennifer\", \"Elisseeff\", role = \"ctb\", email = \"jhe@jhu.edu\", comment = c(ORCID = \"0000-0002-5066-1996\"))\n)", "Description": "dominoSignal is a package developed to analyze cell\nsignaling through ligand - receptor - transcription factor\nnetworks in scRNAseq data. It takes as input information\ntranscriptomic data, requiring counts, z-scored counts, and\ncluster labels, as well as information on transcription factor\nactivation (such as from SCENIC) and a database of ligand and\nreceptor pairings (such as from CellPhoneDB). 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