{ "_id": "6a51d8d39b92047c28d519dd", "Package": "dinoR", "Title": "Differential NOMe-seq analysis", "Version": "1.9.0", "Authors@R": "person(\"Michaela\", \"Schwaiger\",, \"michaela.schwaiger@fmi.ch\",\nrole = c(\"aut\", \"cre\"),\ncomment = c(ORCID = \"0000-0002-4522-7810\"))", "Description": "dinoR tests for significant differences in NOMe-seq\nfootprints between two conditions, using genomic regions of\ninterest (ROI) centered around a landmark, for example a\ntranscription factor (TF) motif. This package takes NOMe-seq\ndata (GCH methylation/protection) in the form of a Ranged\nSummarized Experiment as input. dinoR can be used to group\nsequencing fragments into 3 or 5 categories representing\ncharacteristic footprints (TF bound, nculeosome bound, open\nchromatin), plot the percentage of fragments in each category\nin a heatmap, or averaged across different ROI groups, for\nexample, containing a common TF motif. It is designed to\ncompare footprints between two sample groups, using edgeR's\nquasi-likelihood methods on the total fragment counts per ROI,\nsample, and footprint category.", "License": "MIT + file LICENSE", "Encoding": "UTF-8", "Roxygen": "list(markdown = TRUE)", "RoxygenNote": "7.3.1", "Config/testthat/edition": "3", "VignetteBuilder": "knitr", "LazyData": "false", "biocViews": "NucleosomePositioning, Epigenetics, MethylSeq,\nDifferentialMethylation, Coverage, Transcription, Sequencing,\nSoftware", "URL": "https://github.com/xxxmichixxx/dinoR", "BugReports": "https://github.com/xxxmichixxx/dinoR/issues", "Config/pak/sysreqs": "libicu-dev libpng-dev perl zlib1g-dev", "Repository": "https://bioc.r-universe.dev", "Date/Publication": "2026-04-28 13:02:40 UTC", "RemoteUrl": "https://github.com/bioc/dinoR", "RemoteRef": "HEAD", "RemoteSha": "0fdd65982f6ea095de1494c8fe1de702157a8bc3", "NeedsCompilation": "no", "Packaged": { "Date": "2026-07-11 05:40:26 UTC", "User": "root" }, "Author": 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