{ "_id": "6a17e864acfb0bcc41da2067", "Package": "cytoKernel", "Type": "Package", "Title": "Differential expression using kernel-based score test", "Version": "1.19.0", "Date": "2021-09-27", "Authors@R": "c(person(\"Tusharkanti\", \"Ghosh\",\nemail = \"tusharkantighosh30@gmail.com\",\nrole = c(\"aut\", \"cre\")),\nperson(\"Victor\", \"Lui\",\nrole = c(\"aut\")),\nperson(\"Pratyaydipta\", \"Rudra\",\nrole = c(\"aut\")),\nperson(\"Souvik\", \"Seal\",\nrole = c(\"aut\")),\nperson(\"Thao\", \"Vu\",\nrole = c(\"aut\")),\nperson(\"Elena\", \"Hsieh\",\nrole = c(\"aut\")),\nperson(\"Debashis\", \"Ghosh\",\nrole = c(\"aut\", \"cph\")))", "VignetteBuilder": "knitr", "Encoding": "UTF-8", "License": "GPL-3", "Description": "cytoKernel implements a kernel-based score test to\nidentify differentially expressed features in high-dimensional\nbiological experiments. This approach can be applied across\nmany different high-dimensional biological data including gene\nexpression data and dimensionally reduced cytometry-based\nmarker expression data. In this R package, we implement\nfunctions that compute the feature-wise p values and their\ncorresponding adjusted p values. Additionally, it also computes\nthe feature-wise shrunk effect sizes and their corresponding\nshrunken effect size. Further, it calculates the percent of\ndifferentially expressed features and plots user-friendly\nheatmap of the top differentially expressed features on the\nrows and samples on the columns.", "biocViews": "ImmunoOncology, Proteomics, SingleCell, Software,\nOneChannel, FlowCytometry, DifferentialExpression,\nGeneExpression, Clustering", "BugReports": "https://github.com/Ghoshlab/cytoKernel/issues", "RoxygenNote": "7.1.2", "Config/pak/sysreqs": "libpng-dev perl zlib1g-dev", "Repository": "https://bioc.r-universe.dev", "Date/Publication": "2026-04-28 12:57:00 UTC", "RemoteUrl": "https://github.com/bioc/cytoKernel", "RemoteRef": "HEAD", "RemoteSha": "4506a4f9a9a5f860a79d6f89709aa318778202b0", "NeedsCompilation": "yes", "Packaged": { "Date": "2026-05-28 06:32:31 UTC", "User": "root" }, "Author": "Tusharkanti Ghosh [aut, cre],\nVictor Lui [aut],\nPratyaydipta Rudra [aut],\nSouvik Seal [aut],\nThao Vu [aut],\nElena Hsieh [aut],\nDebashis Ghosh [aut, cph]", "Maintainer": "Tusharkanti Ghosh 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