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  "Title": "Enrichment Analysis of Chemical-Gene Interactions from the\nComparative Toxicogenomics Database",
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  "Authors@R": "person(\ngiven = \"Luigi\",\nfamily = \"Corsaro\",\nrole = c(\"aut\", \"cre\"),\nemail = \"lcorsaro69@gmail.com\",\ncomment = c(ORCID = \"0000-0003-1218-230X\"))",
  "Description": "Identifies chemicals significantly associated with a set\nof genes using data from the Comparative Toxicogenomics\nDatabase (CTD, <https://ctdbase.org>). Supports four enrichment\nmethods through a unified interface: Over-Representation\nAnalysis (ORA) via a hypergeometric test on stats::phyper(),\nGene Set Enrichment Analysis (GSEA) via 'fgsea', the\ncompetitive gene-set test CAMERA via 'limma', and per-sample\nGene Set Variation Analysis (GSVA) via 'GSVA'. Users download\nthe CTD chemical-gene interactions file once, import it with\nimport_CTD(), and then run enrichment_CTD() on either a gene\nlist (ORA, GSEA) or an expression matrix (CAMERA, GSVA). This\npackage does not bundle or redistribute CTD data. Users must\ndownload the required data files directly from\n<https://ctdbase.org> and comply with the CTD data licensing\nterms (see <https://ctdbase.org/about/legal.jsp>).",
  "License": "Apache License 2.0 | file LICENSE",
  "URL": "https://luigicorsaro.com/ctdR/, https://github.com/drake69/ctdR",
  "BugReports": "https://github.com/drake69/ctdR/issues",
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      "page": "ctdR-package",
      "title": "ctdR: Enrichment Analysis of Chemical-Gene Interactions from CTD",
      "topics": [
        "ctdR-package",
        "ctdR"
      ]
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    {
      "page": "as_genesets_CTD",
      "title": "Export CTD Gene Sets for Existing Enrichment Engines",
      "topics": [
        "as_genesets_CTD"
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      "title": "Retrieve Cached CTD Data",
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      "title": "CTD Chemical-Gene Interactions File",
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        "CTDFile",
        "CTDFile-class",
        "import,CTDFile,ANY,ANY-method"
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      ]
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      "title": "Import CTD Chemical-Gene Interaction Data",
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      "title": "Plot Chemical Enrichment Results",
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      ]
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        "From GitHub (latest development version)",
        "Quick start",
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        "Step 2 -- Import into ctdR",
        "Which CTD release did I use?",
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        "Prepare your gene list",
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        "Over-Representation Analysis (ORA)",
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        "Interoperability with existing Bioconductor infrastructure",
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        "Handing the CTD gene sets to another engine",
        "Naming and scope: the \"CTD\" acronym",
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