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Probe-level effects are fitted within subject, so\nsubject identity, array type and chip are absorbed rather than\nmodelled; adjacent probes are grouped by within-subject\nco-methylation; regions are obtained by total-variation\ndenoising with a distance-decaying penalty, which places\nboundaries where the effect track jumps instead of thresholding\na smooth curve; and long-range blocks are called from a\nthree-state hidden semi-Markov model whose transition\nprobabilities decay with genomic distance. Selection stability\nand permutation nulls resample subjects, not samples, so a\nsubject's visit series is never split.", "License": "MIT + file LICENSE", "Encoding": "UTF-8", "VignetteBuilder": "knitr", "biocViews": "DNAMethylation, DifferentialMethylation, Epigenetics,\nMethylationArray, Regression, Software", "BiocType": "Software", "URL": "https://github.com/bioinfbrad/crossarrayEWAS", "BugReports": "https://github.com/bioinfbrad/crossarrayEWAS/issues", "Config/testthat/edition": "3", "Roxygen": "list(markdown = TRUE)", "Config/roxygen2/version": "8.1.0", "Config/pak/sysreqs": "zlib1g-dev", "Repository": "https://bioc.r-universe.dev", "Date/Publication": "2026-10-12 17:32:46 UTC", "RemoteUrl": "https://github.com/bioc/crossarrayEWAS", "RemoteRef": "HEAD", "RemoteSha": "c865b4852887928742d3fe39529bd72a8b07887e", "NeedsCompilation": "no", "Packaged": { "Date": "2026-11-08 15:59:29 UTC", "User": "root" }, "Author": "Katarzyna Kamieniecka [aut, cre] (ORCID:\n),\nSamantha McLean [aut] 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