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  "Title": "Unified Statistical Modeling of Omics Data",
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  "Description": "This package unifies access to Statistal Modeling of Omics\nData. Across linear modeling engines (lm, lme, lmer, limma, and\nwilcoxon). Across coding systems (treatment, difference,\ndeviation, etc). Across model formulae (with/without intercept,\nrandom effect, interaction or nesting). Across omics platforms\n(microarray, rnaseq, msproteomics, affinity proteomics,\nmetabolomics). Across projection methods (pca, pls, sma, lda,\nspls, opls). Across clustering methods (hclust, pam, cmeans).\nAcross survival methods (coxph, survdiff, coin). It provides a\nfast enrichment analysis implementation.",
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  "Date/Publication": "2026-04-28 12:55:12 UTC",
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    "linmod_wilcoxon",
    "LINMODENGINES",
    "list_files",
    "list2mat",
    "loadingmat",
    "loadings",
    "log2counts",
    "log2counts<-",
    "log2cpm",
    "log2cpm<-",
    "log2diffs",
    "log2diffs<-",
    "log2proteins",
    "log2proteins<-",
    "log2sites",
    "log2sites<-",
    "log2tpm",
    "log2tpm<-",
    "log2transform",
    "logical2factor",
    "make_alpha_palette",
    "make_colors",
    "make_volcano_dt",
    "map_fvalues",
    "mat2dt",
    "matrix2sumexp",
    "MAXQUANT_PATTERNS",
    "mclust_breaks",
    "mclust_parameters",
    "mdsplot",
    "merge_compounddiscoverer",
    "merge_fdata",
    "merge_fdt",
    "merge_ffile",
    "merge_sample_excel",
    "merge_sample_file",
    "merge_sdata",
    "merge_sdt",
    "message_df",
    "minusinf_to_na",
    "mixtools_breaks",
    "mixtools_parameters",
    "model_coefs",
    "modeldt",
    "modelfeatures",
    "modelmat",
    "modelvar",
    "modelvec",
    "MSIGCOLLECTIONSHUMAN",
    "MSIGCOLLECTIONSMOUSE",
    "MSIGDIR",
    "na_to_string",
    "na_to_zero",
    "nan_to_na",
    "nfactors",
    "no_nas",
    "object1",
    "object2",
    "OPENTARGETSDIR",
    "opls",
    "order_on_effect",
    "order_on_p",
    "order_on_t",
    "overall_parameters",
    "parse_maxquant_hdrs",
    "pca",
    "pdt",
    "pg_to_canonical",
    "pg_to_isoforms",
    "plot_coef_densities",
    "plot_contrast_venn",
    "plot_contrastogram",
    "plot_data",
    "plot_densities",
    "plot_densities_transforms",
    "plot_design",
    "plot_detections",
    "plot_exprs",
    "plot_exprs_per_coef",
    "plot_feature_boxplots",
    "plot_feature_densities",
    "plot_feature_violins",
    "plot_fit_summary",
    "plot_heatmap",
    "plot_matrix",
    "plot_sample_boxplots",
    "plot_sample_densities",
    "plot_sample_nas",
    "plot_sample_violins",
    "plot_subgroup_nas",
    "plot_subgroup_points",
    "plot_subgroup_violins",
    "plot_summarized_detections",
    "plot_summary",
    "plot_survival",
    "plot_venn",
    "plot_venn_heatmap",
    "plot_violins",
    "plot_violins_transforms",
    "plot_volcano",
    "plot_x_density",
    "plot_xy_density",
    "plot_xy_scatter",
    "plot_y_density",
    "pls",
    "pmat",
    "PRECURSOR_QUANTITY",
    "prep_survival",
    "preprocess_rnaseq_counts",
    "pull_columns",
    "pvalues_estimable",
    "pvar",
    "pvec",
    "quantile_breaks",
    "quantnorm",
    "random_nas",
    "read_affymetrix",
    "read_compounddiscoverer",
    "read_contaminantdt",
    "read_diann",
    "read_diann_pgmatrix",
    "read_diann_phosphodiffs",
    "read_diann_phosphosites",
    "read_diann_proteingroups",
    "read_fragpipe",
    "read_maxquant_phosphosites",
    "read_maxquant_proteingroups",
    "read_metabolon",
    "read_msigdt",
    "read_olink",
    "read_phosphosites",
    "read_proteingroups",
    "read_rectangles",
    "read_rnaseq_bams",
    "read_rnaseq_counts",
    "read_salmon",
    "read_somascan",
    "read_uniprotdt",
    "recollapse",
    "reset_fit",
    "REVIEWED_TO_NUMBER",
    "right.vars",
    "rm_diann_contaminants",
    "rm_missing_in_all_samples",
    "rm_missing_in_some_samples",
    "rm_singleton_samples",
    "rm_unmatched_samples",
    "sampleid_values",
    "sbind",
    "scaledlibsizes",
    "scor",
    "scoremat",
    "scores",
    "sdata",
    "sdata<-",
    "sdist",
    "sdt",
    "sdt<-",
    "slevels",
    "sma",
    "snames",
    "snames<-",
    "split_extract",
    "split_extract_fixed",
    "split_extract_regex",
    "split_features",
    "split_samples",
    "spls",
    "sscale",
    "stepauc",
    "stri_any_regex",
    "stri_detect_fixed_in_collapsed",
    "subgroup_array",
    "subgroup_levels",
    "subgroup_matrix",
    "subgroup_values",
    "subtract_baseline",
    "subtract_differences",
    "subtract_pairs",
    "sumexp_to_groupdt",
    "sumexp_to_longdt",
    "sumexp_to_tsv",
    "sumexp_to_widedt",
    "sumexplist_to_longdt",
    "summarize_fit",
    "survobj",
    "svalues",
    "svalues<-",
    "svars",
    "svars<-",
    "systematic_nas",
    "tag_features",
    "tag_hdlproteins",
    "TAXON_TO_ORGNAME",
    "taxon2org",
    "tdt",
    "TESTS",
    "tmat",
    "tpm",
    "tpm<-",
    "TRANSFORMENGINES",
    "TRANSFORMSTRICT",
    "tvar",
    "tvec",
    "twofactor_sumexp",
    "uncollapse",
    "upfeatures",
    "values",
    "values<-",
    "varlevels_dont_clash",
    "venn_detects",
    "vsn",
    "weights",
    "weights<-",
    "write_ods",
    "write_xl",
    "X",
    "zero_to_na",
    "zscore"
  ],
  "_help": [
    {
      "page": "dot-coxph",
      "title": "Fit onefeature survival",
      "topics": [
        ".coxph",
        ".logrank",
        ".survdiff"
      ]
    },
    {
      "page": "densities",
      "title": "Densities",
      "topics": [
        ".densities",
        "densities"
      ]
    },
    {
      "page": "extract_contrast_features",
      "title": "Extract coefficient features",
      "topics": [
        ".extract_effectsize_features",
        ".extract_fdr_features",
        ".extract_n_features",
        ".extract_p_features",
        "extract_contrast_features"
      ]
    },
    {
      "page": "fit_survival",
      "title": "Fit/Plot survival",
      "topics": [
        ".fit_survival",
        "fit_survival",
        "plot_survival",
        "prep_survival"
      ]
    },
    {
      "page": "dot-merge",
      "title": "Clean Merge",
      "topics": [
        ".merge"
      ]
    },
    {
      "page": "dot-read_compounddiscoverer",
      "title": "Read compound discoverer files as-is",
      "topics": [
        ".read_compounddiscoverer"
      ]
    },
    {
      "page": "dot-read_compounddiscoverer_masslist",
      "title": "Read compound discoverer masslist files as-is",
      "topics": [
        ".read_compounddiscoverer_masslist"
      ]
    },
    {
      "page": "read_diann_proteingroups",
      "title": "Read diann",
      "topics": [
        ".read_diann_precursors",
        ".read_diann_proteingroups",
        "read_diann",
        "read_diann_proteingroups"
      ]
    },
    {
      "page": "dot-read_maxquant_proteingroups",
      "title": "Read proteingroups/phosphosites as-is",
      "topics": [
        ".read_maxquant_phosphosites",
        ".read_maxquant_proteingroups"
      ]
    },
    {
      "page": "read_metabolon",
      "title": "Read metabolon xlsxfile",
      "topics": [
        ".read_metabolon",
        "read_metabolon"
      ]
    },
    {
      "page": "read_rectangles",
      "title": "Read omics data from rectangular file",
      "topics": [
        ".read_rectangles",
        "read_rectangles"
      ]
    },
    {
      "page": "read_rnaseq_counts",
      "title": "Read rnaseq counts/bams",
      "topics": [
        ".read_rnaseq_bams",
        ".read_rnaseq_counts",
        "read_rnaseq_bams",
        "read_rnaseq_counts"
      ]
    },
    {
      "page": "read_somascan",
      "title": "Read somascan adatfile",
      "topics": [
        ".read_somascan",
        "read_somascan"
      ]
    },
    {
      "page": "abstract_fit",
      "title": "Abstract model fit",
      "topics": [
        "abstract_fit"
      ]
    },
    {
      "page": "add_adjusted_pvalues",
      "title": "Add adjusted pvalues",
      "topics": [
        "add_adjusted_pvalues",
        "add_adjusted_pvalues.data.table",
        "add_adjusted_pvalues.NULL",
        "add_adjusted_pvalues.SummarizedExperiment"
      ]
    },
    {
      "page": "add_assay_means",
      "title": "Add assay means",
      "topics": [
        "add_assay_means"
      ]
    },
    {
      "page": "add_facetvars",
      "title": "Add facetvars",
      "topics": [
        "add_facetvars"
      ]
    },
    {
      "page": "add_opentargets_by_uniprot",
      "title": "Add opentargets annotations",
      "topics": [
        "add_opentargets_by_uniprot"
      ]
    },
    {
      "page": "add_psp",
      "title": "Add psp",
      "topics": [
        "add_psp"
      ]
    },
    {
      "page": "add_smiles",
      "title": "Add smiles",
      "topics": [
        "add_smiles"
      ]
    },
    {
      "page": "altenrich",
      "title": "Alternative Enrichment Analysis",
      "topics": [
        "altenrich"
      ]
    },
    {
      "page": "analysis",
      "title": "Get/set analysis",
      "topics": [
        "analysis",
        "analysis,SummarizedExperiment-method",
        "analysis<-",
        "analysis<-,SummarizedExperiment,list-method"
      ]
    },
    {
      "page": "analyze",
      "title": "Analyze",
      "topics": [
        "analyze"
      ]
    },
    {
      "page": "annotate_compounddiscoverer",
      "title": "Read compound discoverer output",
      "topics": [
        "annotate_compounddiscoverer"
      ]
    },
    {
      "page": "annotate_maxquant",
      "title": "Annotate maxquant",
      "topics": [
        "annotate_maxquant"
      ]
    },
    {
      "page": "annotate_uniprot_rest",
      "title": "Annotate uniprot/ensp",
      "topics": [
        "annotate_uniprot_rest"
      ]
    },
    {
      "page": "assert_is_valid_sumexp",
      "title": "Assert that x is a valid SummarizedExperiment",
      "topics": [
        "assert_is_valid_sumexp"
      ]
    },
    {
      "page": "AUTONOMICS_DATASETS",
      "title": "Data used in examples/vignette/tests/longtests",
      "topics": [
        "AUTONOMICS_DATASETS"
      ]
    },
    {
      "page": "awblinmod",
      "title": "General Linear Modeling (across-within-between interface)",
      "topics": [
        "awblinmod",
        "awblinmod_limma",
        "awblinmod_lm",
        "awblinmod_lme",
        "awblinmod_lmer"
      ]
    },
    {
      "page": "biplot",
      "title": "Biplot",
      "topics": [
        "biplot"
      ]
    },
    {
      "page": "biplot_corrections",
      "title": "Biplot batch corrections",
      "topics": [
        "biplot_corrections"
      ]
    },
    {
      "page": "biplot_covariates",
      "title": "Biplot covariates",
      "topics": [
        "biplot_covariates"
      ]
    },
    {
      "page": "block_has_two_levels",
      "title": "Block has two levels",
      "topics": [
        "block_has_two_levels"
      ]
    },
    {
      "page": "block2limma",
      "title": "block2limma",
      "topics": [
        "block2limma",
        "block2limma.character",
        "block2limma.formula",
        "block2limma.list",
        "block2limma.NULL"
      ]
    },
    {
      "page": "block2lm",
      "title": "block2lm",
      "topics": [
        "block2lm",
        "block2lm.character",
        "block2lm.formula",
        "block2lm.list",
        "block2lm.NULL"
      ]
    },
    {
      "page": "block2lme",
      "title": "block2lme",
      "topics": [
        "block2lme",
        "block2lme.character",
        "block2lme.formula",
        "block2lme.list"
      ]
    },
    {
      "page": "block2lmer",
      "title": "block2lmer",
      "topics": [
        "block2lmer",
        "block2lmer.character",
        "block2lmer.formula",
        "block2lmer.list"
      ]
    },
    {
      "page": "center",
      "title": "Center samples",
      "topics": [
        "center",
        "center_mean",
        "center_median"
      ]
    },
    {
      "page": "code",
      "title": "Contrast Code Factor",
      "topics": [
        "code",
        "code.character",
        "code.data.table",
        "code.factor",
        "code.logical",
        "code.numeric",
        "code_control",
        "code_deviation",
        "code_deviation_first",
        "code_diff",
        "code_diff_forward",
        "code_helmert",
        "code_helmert_forward",
        "contr.diff",
        "contr.treatment.explicit"
      ]
    },
    {
      "page": "collapsed_entrezg_to_symbol",
      "title": "Collapsed entrezg to genesymbol",
      "topics": [
        "collapsed_entrezg_to_symbol"
      ]
    },
    {
      "page": "COMPOUNDDISCOVERER_PATTERNS",
      "title": "compound discoverer quantity patterns",
      "topics": [
        "COMPOUNDDISCOVERER_PATTERNS"
      ]
    },
    {
      "page": "model_coefs",
      "title": "Get model coefs",
      "topics": [
        "contrast_coefs",
        "model_coefs"
      ]
    },
    {
      "page": "contrast_subgroup_cols",
      "title": "Row/Col contrasts",
      "topics": [
        "contrast_subgroup_cols",
        "contrast_subgroup_rows"
      ]
    },
    {
      "page": "contrastdt",
      "title": "Get contrastdt",
      "topics": [
        "contrastdt"
      ]
    },
    {
      "page": "count_in",
      "title": "Count/Collapse in/outside intersection",
      "topics": [
        "collapse_in",
        "collapse_in.character",
        "collapse_in.factor",
        "collapse_in.list",
        "count_in",
        "count_in.character",
        "count_in.factor",
        "count_in.list",
        "count_out",
        "count_out.character",
        "count_out.factor",
        "count_out.list"
      ]
    },
    {
      "page": "counts",
      "title": "Get/Set counts",
      "topics": [
        "counts",
        "counts,SummarizedExperiment-method",
        "counts<-",
        "counts<-,SummarizedExperiment,matrix-method",
        "counts<-,SummarizedExperiment,NULL-method",
        "counts<-,SummarizedExperiment,numeric-method"
      ]
    },
    {
      "page": "counts2cpm",
      "title": "Convert between counts and cpm/tpm",
      "topics": [
        "counts2cpm",
        "cpm2counts"
      ]
    },
    {
      "page": "counts2tpm",
      "title": "counts to tpm",
      "topics": [
        "counts2tpm"
      ]
    },
    {
      "page": "cpm",
      "title": "Get/Set cpm",
      "topics": [
        "cpm",
        "cpm,SummarizedExperiment-method",
        "cpm<-",
        "cpm<-,SummarizedExperiment,matrix-method",
        "cpm<-,SummarizedExperiment,numeric-method"
      ]
    },
    {
      "page": "create_design",
      "title": "Create design matrix",
      "topics": [
        "create_design",
        "create_design.data.table",
        "create_design.SummarizedExperiment"
      ]
    },
    {
      "page": "download_data",
      "title": "Download autonomics example data",
      "topics": [
        "DATADIR",
        "download_data"
      ]
    },
    {
      "page": "default_formula",
      "title": "Create default formula",
      "topics": [
        "default_formula"
      ]
    },
    {
      "page": "default_geom",
      "title": "Default geom",
      "topics": [
        "default_geom"
      ]
    },
    {
      "page": "default_sfile",
      "title": "Default sfile",
      "topics": [
        "default_sfile"
      ]
    },
    {
      "page": "defaultmsigfile",
      "title": "Default msigdb file",
      "topics": [
        "defaultmsigfile"
      ]
    },
    {
      "page": "demultiplex",
      "title": "Demultiplex snames",
      "topics": [
        "demultiplex"
      ]
    },
    {
      "page": "dequantify",
      "title": "Dequantify maxquant snames",
      "topics": [
        "dequantify"
      ]
    },
    {
      "page": "dequantify_compounddiscoverer",
      "title": "dequantify_compounddiscoverer compound discoverer snames",
      "topics": [
        "dequantify_compounddiscoverer"
      ]
    },
    {
      "page": "DIMREDENGINES",
      "title": "Dimension Reduction Methods",
      "topics": [
        "DIMREDENGINES",
        "DIMREDSUPER",
        "DIMREDUN"
      ]
    },
    {
      "page": "download_gtf",
      "title": "Download GTF file",
      "topics": [
        "download_gtf"
      ]
    },
    {
      "page": "download_mcclain21",
      "title": "Download mcclain21 data",
      "topics": [
        "download_mcclain21"
      ]
    },
    {
      "page": "dt2mat",
      "title": "`data.table` to `matrix`",
      "topics": [
        "dt2mat",
        "mat2dt"
      ]
    },
    {
      "page": "enrichment",
      "title": "Enrichment analysis",
      "topics": [
        "enrichment"
      ]
    },
    {
      "page": "taxon2org",
      "title": "taxon/ens to organism",
      "topics": [
        "ens2org",
        "taxon2org"
      ]
    },
    {
      "page": "entrezg_to_symbol",
      "title": "Entrezg to genesymbol",
      "topics": [
        "entrezg_to_symbol"
      ]
    },
    {
      "page": "extract_rectangle",
      "title": "Extract rectangle from omics file, data.table, or matrix",
      "topics": [
        "extract_rectangle",
        "extract_rectangle.character",
        "extract_rectangle.data.table",
        "extract_rectangle.matrix"
      ]
    },
    {
      "page": "factorize",
      "title": "Factorize/Bin",
      "topics": [
        "bin",
        "bin.character",
        "bin.factor",
        "bin.logical",
        "bin.matrix",
        "bin.numeric",
        "bin.SummarizedExperiment",
        "bin_assay",
        "factorize",
        "factorize.character",
        "factorize.factor",
        "factorize.logical",
        "factorize.matrix",
        "factorize.numeric",
        "factorize.SummarizedExperiment",
        "factorize_assay"
      ]
    },
    {
      "page": "fcluster",
      "title": "Cluster features",
      "topics": [
        "fcluster"
      ]
    },
    {
      "page": "fdata",
      "title": "Get/Set sample/feature data",
      "topics": [
        "fdata",
        "fdata,SummarizedExperiment-method",
        "fdata<-",
        "fdata<-,SummarizedExperiment,data.frame-method",
        "fdt",
        "fdt,SummarizedExperiment-method",
        "fdt<-",
        "fdt<-,SummarizedExperiment,data.table-method",
        "sdata",
        "sdata,SummarizedExperiment-method",
        "sdata<-",
        "sdata<-,SummarizedExperiment,data.frame-method",
        "sdata<-,SummarizedExperiment,DataFrame-method",
        "sdt",
        "sdt,SummarizedExperiment-method",
        "sdt<-",
        "sdt<-,SummarizedExperiment,data.table-method"
      ]
    },
    {
      "page": "fdr2p",
      "title": "fdr to p",
      "topics": [
        "fdr2p"
      ]
    },
    {
      "page": "filter_exprs_replicated_in_some_subgroup",
      "title": "Filter features with replicated expression in some subgroup",
      "topics": [
        "filter_exprs_replicated_in_some_subgroup"
      ]
    },
    {
      "page": "filter_features",
      "title": "Filter features on condition",
      "topics": [
        "filter_features"
      ]
    },
    {
      "page": "filter_medoid",
      "title": "Filter medoid sample",
      "topics": [
        "filter_medoid"
      ]
    },
    {
      "page": "filter_samples",
      "title": "Filter samples on condition",
      "topics": [
        "filter_samples"
      ]
    },
    {
      "page": "fits",
      "title": "Get fit models",
      "topics": [
        "coefs",
        "coefs.data.table",
        "coefs.factor",
        "coefs.NULL",
        "coefs.SummarizedExperiment",
        "fitcoefs",
        "fits",
        "fits.data.table",
        "fits.NULL",
        "fits.SummarizedExperiment"
      ]
    },
    {
      "page": "fix_xlgenes",
      "title": "Fix excel genes",
      "topics": [
        "fix_xlgenes"
      ]
    },
    {
      "page": "flevels",
      "title": "Get fvar levels",
      "topics": [
        "flevels"
      ]
    },
    {
      "page": "fnames",
      "title": "Get/Set fnames",
      "topics": [
        "fnames",
        "fnames,SummarizedExperiment-method",
        "fnames<-",
        "fnames<-,SummarizedExperiment,character-method"
      ]
    },
    {
      "page": "formula2str",
      "title": "formula to string",
      "topics": [
        "formula2str"
      ]
    },
    {
      "page": "ftype",
      "title": "Feature type",
      "topics": [
        "ftype"
      ]
    },
    {
      "page": "fvalues",
      "title": "Get fvalues",
      "topics": [
        "fvalues"
      ]
    },
    {
      "page": "fvars",
      "title": "Get/Set fvars",
      "topics": [
        "fvars",
        "fvars,SummarizedExperiment-method",
        "fvars<-",
        "fvars<-,SummarizedExperiment,character-method"
      ]
    },
    {
      "page": "genome_to_orgdb",
      "title": "Get corresponding orgdb",
      "topics": [
        "genome_to_orgdb"
      ]
    },
    {
      "page": "group_by_level",
      "title": "group by level",
      "topics": [
        "group_by_level",
        "group_by_level.character",
        "group_by_level.data.table",
        "group_by_level.factor"
      ]
    },
    {
      "page": "guess_compounddiscoverer_quantity",
      "title": "Guess compound discoverer quantity from snames",
      "topics": [
        "guess_compounddiscoverer_quantity"
      ]
    },
    {
      "page": "guess_fitsep",
      "title": "guess fitsep",
      "topics": [
        "guess_fitsep",
        "guess_fitsep.data.table",
        "guess_fitsep.SummarizedExperiment"
      ]
    },
    {
      "page": "guess_maxquant_quantity",
      "title": "Guess maxquant quantity from snames",
      "topics": [
        "guess_maxquant_quantity"
      ]
    },
    {
      "page": "guess_sep",
      "title": "Guess separator",
      "topics": [
        "guess_sep",
        "guess_sep.character",
        "guess_sep.factor",
        "guess_sep.numeric",
        "guess_sep.SummarizedExperiment"
      ]
    },
    {
      "page": "has_multiple_levels",
      "title": "Variable has multiple levels?",
      "topics": [
        "has_multiple_levels",
        "has_multiple_levels.character",
        "has_multiple_levels.data.table",
        "has_multiple_levels.factor",
        "has_multiple_levels.numeric",
        "has_multiple_levels.SummarizedExperiment"
      ]
    },
    {
      "page": "hdlproteins",
      "title": "hdl proteomewatch proteins",
      "topics": [
        "hdlproteins"
      ]
    },
    {
      "page": "impute",
      "title": "Impute",
      "topics": [
        "impute",
        "impute.matrix",
        "impute.numeric",
        "impute.SummarizedExperiment"
      ]
    },
    {
      "page": "installed",
      "title": "Is package installed?",
      "topics": [
        "installed"
      ]
    },
    {
      "page": "invert_subgroups",
      "title": "Invert subgroups",
      "topics": [
        "invert_subgroups"
      ]
    },
    {
      "page": "is_character_matrix",
      "title": "Is character matrix",
      "topics": [
        "assert_character_matrix",
        "is_character_matrix"
      ]
    },
    {
      "page": "is_collapsed_subset",
      "title": "Is collapsed subset",
      "topics": [
        "is_collapsed_subset"
      ]
    },
    {
      "page": "is_compounddiscoverer_output",
      "title": "Is compounddiscoverer output?",
      "topics": [
        "is_compounddiscoverer_output"
      ]
    },
    {
      "page": "is_correlation_matrix",
      "title": "Assert correlation matrix",
      "topics": [
        "assert_correlation_matrix",
        "is_correlation_matrix"
      ]
    },
    {
      "page": "is_diann_report",
      "title": "Is diann report ?",
      "topics": [
        "assert_compounddiscoverer_output",
        "assert_diann_report",
        "assert_fragpipe_tsv",
        "assert_maxquant_phosphosites",
        "assert_maxquant_proteingroups",
        "is_diann_report"
      ]
    },
    {
      "page": "is_fastadt",
      "title": "Is fastadt",
      "topics": [
        "assert_fastadt",
        "is_fastadt"
      ]
    },
    {
      "page": "is_file",
      "title": "Is a file?",
      "topics": [
        "is_file"
      ]
    },
    {
      "page": "is_fraction",
      "title": "Is fraction",
      "topics": [
        "assert_is_fraction",
        "is_fraction"
      ]
    },
    {
      "page": "is_fragpipe_tsv",
      "title": "Is fragpipe file?",
      "topics": [
        "is_fragpipe_tsv"
      ]
    },
    {
      "page": "is_imputed",
      "title": "Get/set is_imputed",
      "topics": [
        "is_imputed",
        "is_imputed,SummarizedExperiment-method",
        "is_imputed<-",
        "is_imputed<-,SummarizedExperiment,matrix-method",
        "is_imputed<-,SummarizedExperiment,NULL-method"
      ]
    },
    {
      "page": "is_maxquant_phosphosites",
      "title": "Is maxquant phosphosites file?",
      "topics": [
        "is_maxquant_phosphosites"
      ]
    },
    {
      "page": "is_maxquant_proteingroups",
      "title": "Is maxquant proteingroups file?",
      "topics": [
        "is_maxquant_proteingroups"
      ]
    },
    {
      "page": "all_non_numeric",
      "title": "Are all variables non-numeric ?",
      "topics": [
        "all_non_numeric",
        "is_non_numeric"
      ]
    },
    {
      "page": "is_positive_number",
      "title": "Is positive number",
      "topics": [
        "assert_positive_number",
        "assert_weakly_positive_number",
        "is_positive_number",
        "is_weakly_positive_number"
      ]
    },
    {
      "page": "is_scalar_subset",
      "title": "Is scalar subset",
      "topics": [
        "assert_scalar_subset",
        "is_scalar_subset"
      ]
    },
    {
      "page": "is_sig",
      "title": "Is significant?",
      "topics": [
        "is_sig"
      ]
    },
    {
      "page": "is_valid_formula",
      "title": "Is valid formula",
      "topics": [
        "assert_valid_formula",
        "is_valid_formula"
      ]
    },
    {
      "page": "keep_estimable_features",
      "title": "Keep estimable features",
      "topics": [
        "keep_estimable_features"
      ]
    },
    {
      "page": "label2index",
      "title": "Convert labels into indices",
      "topics": [
        "label2index"
      ]
    },
    {
      "page": "factor.vars",
      "title": "Get factor variables",
      "topics": [
        "factor.vars",
        "factor.vars,formula,data.table-method",
        "factor.vars,formula,SummarizedExperiment-method",
        "left.vars",
        "right.vars"
      ]
    },
    {
      "page": "LINMOD",
      "title": "General Linear Model",
      "topics": [
        "fit_limma",
        "fit_lm",
        "fit_lme",
        "fit_lmer",
        "fit_wilcoxon",
        "LINMOD",
        "linmod_limma",
        "linmod_lm",
        "linmod_lme",
        "linmod_lmer",
        "linmod_wilcoxon"
      ]
    },
    {
      "page": "LINMODENGINES",
      "title": "Linear Modeling Engines",
      "topics": [
        "LINMODENGINES"
      ]
    },
    {
      "page": "list_files",
      "title": "list files",
      "topics": [
        "list_files"
      ]
    },
    {
      "page": "list2mat",
      "title": "list to matrix",
      "topics": [
        "list2mat"
      ]
    },
    {
      "page": "log2counts",
      "title": "Get/Set log2counts",
      "topics": [
        "log2counts",
        "log2counts,SummarizedExperiment-method",
        "log2counts<-",
        "log2counts<-,SummarizedExperiment,matrix-method",
        "log2counts<-,SummarizedExperiment,numeric-method"
      ]
    },
    {
      "page": "log2cpm",
      "title": "Get/Set log2cpm",
      "topics": [
        "log2cpm",
        "log2cpm,SummarizedExperiment-method",
        "log2cpm<-",
        "log2cpm<-,SummarizedExperiment,matrix-method",
        "log2cpm<-,SummarizedExperiment,numeric-method"
      ]
    },
    {
      "page": "log2diffs",
      "title": "Get/Set log2diffs",
      "topics": [
        "log2diffs",
        "log2diffs,SummarizedExperiment-method",
        "log2diffs<-",
        "log2diffs<-,SummarizedExperiment,matrix-method",
        "log2diffs<-,SummarizedExperiment,numeric-method"
      ]
    },
    {
      "page": "log2proteins",
      "title": "Get/Set log2proteins",
      "topics": [
        "log2proteins",
        "log2proteins,SummarizedExperiment-method",
        "log2proteins<-",
        "log2proteins<-,SummarizedExperiment,matrix-method",
        "log2proteins<-,SummarizedExperiment,numeric-method"
      ]
    },
    {
      "page": "log2sites",
      "title": "Get/Set log2sites",
      "topics": [
        "log2sites",
        "log2sites,SummarizedExperiment-method",
        "log2sites<-",
        "log2sites<-,SummarizedExperiment,matrix-method",
        "log2sites<-,SummarizedExperiment,numeric-method"
      ]
    },
    {
      "page": "log2tpm",
      "title": "Get/Set log2tpm",
      "topics": [
        "log2tpm",
        "log2tpm,SummarizedExperiment-method",
        "log2tpm<-",
        "log2tpm<-,SummarizedExperiment,matrix-method",
        "log2tpm<-,SummarizedExperiment,numeric-method"
      ]
    },
    {
      "page": "log2transform",
      "title": "Transform values",
      "topics": [
        "exp2transform",
        "fscale",
        "invnorm",
        "log2transform",
        "quantnorm",
        "sscale",
        "vsn",
        "zscore"
      ]
    },
    {
      "page": "logical2factor",
      "title": "logical to factor",
      "topics": [
        "factor2logical",
        "logical2factor"
      ]
    },
    {
      "page": "make_alpha_palette",
      "title": "Make alpha palette",
      "topics": [
        "make_alpha_palette"
      ]
    },
    {
      "page": "make_colors",
      "title": "Make colors",
      "topics": [
        "make_colors"
      ]
    },
    {
      "page": "make_volcano_dt",
      "title": "Create volcano datatable",
      "topics": [
        "make_volcano_dt"
      ]
    },
    {
      "page": "map_fvalues",
      "title": "Map fvalues",
      "topics": [
        "map_fvalues"
      ]
    },
    {
      "page": "matrix2sumexp",
      "title": "Convert matrix into SummarizedExperiment",
      "topics": [
        "matrix2sumexp"
      ]
    },
    {
      "page": "MAXQUANT_PATTERNS",
      "title": "maxquant quantity patterns",
      "topics": [
        "MAXQUANT_PATTERNS"
      ]
    },
    {
      "page": "mclust_breaks",
      "title": "Mixture/Quantile breaks",
      "topics": [
        "mclust_breaks",
        "mixtools_breaks",
        "quantile_breaks"
      ]
    },
    {
      "page": "fcor",
      "title": "Feature correlations/distances",
      "topics": [
        "fcor",
        "fdist",
        "mdsplot",
        "scor",
        "sdist"
      ]
    },
    {
      "page": "merge_compounddiscoverer",
      "title": "merge compound discoverer files",
      "topics": [
        "merge_compounddiscoverer"
      ]
    },
    {
      "page": "merge_sample_excel",
      "title": "Merge sample excel",
      "topics": [
        "merge_sample_excel"
      ]
    },
    {
      "page": "merge_sample_file",
      "title": "Merge sample / feature file",
      "topics": [
        "merge_ffile",
        "merge_sample_file"
      ]
    },
    {
      "page": "merge_sdata",
      "title": "Merge sample/feature dt",
      "topics": [
        "merge_fdata",
        "merge_fdt",
        "merge_sdata",
        "merge_sdt"
      ]
    },
    {
      "page": "message_df",
      "title": "message dataframe",
      "topics": [
        "message_df"
      ]
    },
    {
      "page": "modelvar",
      "title": "Get model variable",
      "topics": [
        "abstractvar",
        "abstractvar.data.table",
        "abstractvar.SummarizedExperiment",
        "abstractvec",
        "abstractvec.data.table",
        "abstractvec.SummarizedExperiment",
        "downfeatures",
        "effectdt",
        "effectmat",
        "effectsizemat",
        "effectvar",
        "effectvec",
        "fdrmat",
        "fdrvar",
        "fdrvec",
        "modeldt",
        "modeldt.data.table",
        "modeldt.NULL",
        "modeldt.SummarizedExperiment",
        "modelfeatures",
        "modelfeatures.data.table",
        "modelfeatures.SummarizedExperiment",
        "modelmat",
        "modelvar",
        "modelvar.data.table",
        "modelvar.NULL",
        "modelvar.SummarizedExperiment",
        "modelvec",
        "modelvec.data.table",
        "modelvec.SummarizedExperiment",
        "pdt",
        "pmat",
        "pvar",
        "pvec",
        "tdt",
        "tmat",
        "tvar",
        "tvec",
        "upfeatures"
      ]
    },
    {
      "page": "MSIGCOLLECTIONSHUMAN",
      "title": "Human/Mouse Msigdb Collections",
      "topics": [
        "MSIGCOLLECTIONSHUMAN",
        "MSIGCOLLECTIONSMOUSE"
      ]
    },
    {
      "page": "MSIGDIR",
      "title": "local msigdb dir",
      "topics": [
        "MSIGDIR"
      ]
    },
    {
      "page": "split_extract_fixed",
      "title": "stri_split and extract",
      "topics": [
        "nfactors",
        "split_extract",
        "split_extract_fixed",
        "split_extract_regex"
      ]
    },
    {
      "page": "object1",
      "title": "Example objects for binding",
      "topics": [
        "object1",
        "object2"
      ]
    },
    {
      "page": "OPENTARGETSDIR",
      "title": "opentargets dir",
      "topics": [
        "OPENTARGETSDIR"
      ]
    },
    {
      "page": "order_on_p",
      "title": "Order on p",
      "topics": [
        "order_on_effect",
        "order_on_p",
        "order_on_t"
      ]
    },
    {
      "page": "overall_parameters",
      "title": "Distribution parameters",
      "topics": [
        "mclust_parameters",
        "mixtools_parameters",
        "overall_parameters"
      ]
    },
    {
      "page": "pca",
      "title": "PCA, SMA, LDA, PLS, SPLS, OPLS",
      "topics": [
        "lda",
        "opls",
        "pca",
        "pls",
        "sma",
        "spls"
      ]
    },
    {
      "page": "pg_to_canonical",
      "title": "proteingroup to isoforms",
      "topics": [
        "pg_to_canonical",
        "pg_to_isoforms"
      ]
    },
    {
      "page": "plot_coef_densities",
      "title": "Plot contrast densities",
      "topics": [
        "plot_coef_densities"
      ]
    },
    {
      "page": "plot_contrast_venn",
      "title": "Plot contrast venn",
      "topics": [
        "plot_contrast_venn"
      ]
    },
    {
      "page": "plot_contrastogram",
      "title": "Plot contrastogram",
      "topics": [
        "plot_contrastogram"
      ]
    },
    {
      "page": "plot_data",
      "title": "Plot data",
      "topics": [
        "plot_data"
      ]
    },
    {
      "page": "plot_densities",
      "title": "Plot sample/feature distributions",
      "topics": [
        "plot_densities",
        "plot_feature_densities",
        "plot_sample_densities"
      ]
    },
    {
      "page": "explore-transforms",
      "title": "Visually evaluate transformation effects",
      "topics": [
        "biplot_transforms",
        "biplot_transforms_assays",
        "plot_densities_transforms",
        "plot_violins_transforms"
      ]
    },
    {
      "page": "plot_design",
      "title": "Plot model",
      "topics": [
        "plot_design"
      ]
    },
    {
      "page": "plot_exprs",
      "title": "Plot exprs for coef",
      "topics": [
        "plot_exprs",
        "plot_feature_boxplots",
        "plot_sample_boxplots"
      ]
    },
    {
      "page": "plot_exprs_per_coef",
      "title": "Plot exprs per coef",
      "topics": [
        "plot_exprs_per_coef"
      ]
    },
    {
      "page": "plot_fit_summary",
      "title": "Plot fit summary",
      "topics": [
        "plot_fit_summary"
      ]
    },
    {
      "page": "plot_heatmap",
      "title": "Plot heatmap",
      "topics": [
        "plot_heatmap"
      ]
    },
    {
      "page": "plot_matrix",
      "title": "Plot binary matrix",
      "topics": [
        "plot_matrix"
      ]
    },
    {
      "page": "plot_detections",
      "title": "Plot (summarized) detections",
      "topics": [
        "plot_detections",
        "plot_sample_nas",
        "plot_subgroup_nas",
        "plot_summarized_detections"
      ]
    },
    {
      "page": "plot_subgroup_points",
      "title": "Plot features",
      "topics": [
        "plot_subgroup_points"
      ]
    },
    {
      "page": "plot_summary",
      "title": "Plot summary",
      "topics": [
        "plot_summary"
      ]
    },
    {
      "page": "plot_venn",
      "title": "Plot venn",
      "topics": [
        "plot_venn"
      ]
    },
    {
      "page": "plot_venn_heatmap",
      "title": "Plot venn heatmap",
      "topics": [
        "plot_venn_heatmap"
      ]
    },
    {
      "page": "plot_violins",
      "title": "Plot sample/feature violins",
      "topics": [
        "plot_feature_violins",
        "plot_sample_violins",
        "plot_subgroup_violins",
        "plot_violins"
      ]
    },
    {
      "page": "plot_volcano",
      "title": "Plot volcano",
      "topics": [
        "plot_volcano"
      ]
    },
    {
      "page": "plot_xy_density",
      "title": "Plot xy densities",
      "topics": [
        "plot_xy_density",
        "plot_xy_scatter",
        "plot_x_density",
        "plot_y_density"
      ]
    },
    {
      "page": "PRECURSOR_QUANTITY",
      "title": "diann precursor quantity",
      "topics": [
        "PRECURSOR_QUANTITY"
      ]
    },
    {
      "page": "preprocess_rnaseq_counts",
      "title": "Preprocess RNAseq counts",
      "topics": [
        "preprocess_rnaseq_counts"
      ]
    },
    {
      "page": "pull_columns",
      "title": "Pull columns in a dataframe to the front",
      "topics": [
        "pull_columns"
      ]
    },
    {
      "page": "pvalues_estimable",
      "title": "Are coefs/pvalues estimable",
      "topics": [
        "coefs_estimable",
        "pvalues_estimable"
      ]
    },
    {
      "page": "read_affymetrix",
      "title": "Read affymetrix microarray",
      "topics": [
        "read_affymetrix"
      ]
    },
    {
      "page": "read_compounddiscoverer",
      "title": "Read compound discoverer output",
      "topics": [
        "read_compounddiscoverer"
      ]
    },
    {
      "page": "read_diann_phosphodiffs",
      "title": "Read diann phosphosites",
      "topics": [
        "read_diann_pgmatrix",
        "read_diann_phosphodiffs",
        "read_diann_phosphosites"
      ]
    },
    {
      "page": "read_fragpipe",
      "title": "Read fragpipe",
      "topics": [
        "read_fragpipe"
      ]
    },
    {
      "page": "read_maxquant_phosphosites",
      "title": "Read maxquant phosphosites",
      "topics": [
        "read_maxquant_phosphosites",
        "read_phosphosites"
      ]
    },
    {
      "page": "read_maxquant_proteingroups",
      "title": "Read maxquant proteingroups",
      "topics": [
        "read_maxquant_proteingroups",
        "read_proteingroups"
      ]
    },
    {
      "page": "read_msigdt",
      "title": "Read msigdb datatable",
      "topics": [
        "read_msigdt"
      ]
    },
    {
      "page": "read_olink",
      "title": "Read olink file",
      "topics": [
        "read_olink"
      ]
    },
    {
      "page": "read_salmon",
      "title": "Read salmon",
      "topics": [
        "read_salmon"
      ]
    },
    {
      "page": "read_uniprotdt",
      "title": "Read fasta hdrs",
      "topics": [
        "parse_maxquant_hdrs",
        "read_contaminantdt",
        "read_uniprotdt"
      ]
    },
    {
      "page": "reset_fit",
      "title": "Reset fit",
      "topics": [
        "reset_fit"
      ]
    },
    {
      "page": "rm_diann_contaminants",
      "title": "Rm contaminants",
      "topics": [
        "rm_diann_contaminants"
      ]
    },
    {
      "page": "rm_missing_in_some_samples",
      "title": "Rm features missing in some samples",
      "topics": [
        "rm_missing_in_all_samples",
        "rm_missing_in_some_samples"
      ]
    },
    {
      "page": "rm_unmatched_samples",
      "title": "rm unmatched/singleton samples",
      "topics": [
        "rm_singleton_samples",
        "rm_unmatched_samples"
      ]
    },
    {
      "page": "sbind",
      "title": "Sample/Feature/Assay bind",
      "topics": [
        "abind",
        "fbind",
        "sbind"
      ]
    },
    {
      "page": "scaledlibsizes",
      "title": "Get tmm-scaled libsizes",
      "topics": [
        "scaledlibsizes"
      ]
    },
    {
      "page": "scoremat",
      "title": "Extract scores/loadings",
      "topics": [
        "loadingmat",
        "loadings",
        "scoremat",
        "scores"
      ]
    },
    {
      "page": "slevels",
      "title": "Get slevels",
      "topics": [
        "slevels",
        "subgroup_levels"
      ]
    },
    {
      "page": "snames",
      "title": "Get/Set snames",
      "topics": [
        "snames",
        "snames,SummarizedExperiment-method",
        "snames<-",
        "snames<-,SummarizedExperiment,character-method"
      ]
    },
    {
      "page": "split_samples",
      "title": "Split samples",
      "topics": [
        "cbind_imputed",
        "split_features",
        "split_samples"
      ]
    },
    {
      "page": "stepauc",
      "title": "Compute step auc",
      "topics": [
        "stepauc"
      ]
    },
    {
      "page": "stri_any_regex",
      "title": "Does any string have a regex",
      "topics": [
        "stri_any_regex"
      ]
    },
    {
      "page": "stri_detect_fixed_in_collapsed",
      "title": "Detect fixed patterns in collapsed strings",
      "topics": [
        "stri_detect_fixed_in_collapsed"
      ]
    },
    {
      "page": "subgroup_matrix",
      "title": "Get subgroup matrix",
      "topics": [
        "subgroup_array",
        "subgroup_matrix"
      ]
    },
    {
      "page": "subtract_baseline",
      "title": "Subtract baseline",
      "topics": [
        "subtract_baseline",
        "subtract_differences",
        "subtract_pairs"
      ]
    },
    {
      "page": "sumexp_to_tsv",
      "title": "Write sumexp to tsv",
      "topics": [
        "sumexp_to_tsv"
      ]
    },
    {
      "page": "sumexp_to_longdt",
      "title": "SummarizedExperiment to data.table",
      "topics": [
        "sumexp_to_groupdt",
        "sumexp_to_longdt",
        "sumexp_to_widedt"
      ]
    },
    {
      "page": "sumexplist_to_longdt",
      "title": "SummarizedExperiment list to long data.table",
      "topics": [
        "sumexplist_to_longdt"
      ]
    },
    {
      "page": "summarize_fit",
      "title": "Summarize fit",
      "topics": [
        "summarize_fit",
        "summarize_fit.data.table",
        "summarize_fit.SummarizedExperiment"
      ]
    },
    {
      "page": "survobj",
      "title": "Survival analysis example",
      "topics": [
        "survobj"
      ]
    },
    {
      "page": "svalues",
      "title": "Get/Set svalues",
      "topics": [
        "sampleid_values",
        "subgroup_values",
        "svalues",
        "svalues<-",
        "svalues<-,SummarizedExperiment,character-method"
      ]
    },
    {
      "page": "svars",
      "title": "Get/Set svars",
      "topics": [
        "svars",
        "svars,MultiAssayExperiment-method",
        "svars,SummarizedExperiment-method",
        "svars<-",
        "svars<-,MultiAssayExperiment,character-method",
        "svars<-,SummarizedExperiment,character-method"
      ]
    },
    {
      "page": "systematic_nas",
      "title": "Is systematic/random/full NA",
      "topics": [
        "no_nas",
        "random_nas",
        "systematic_nas"
      ]
    },
    {
      "page": "tag_features",
      "title": "Tag features",
      "topics": [
        "tag_features"
      ]
    },
    {
      "page": "tag_hdlproteins",
      "title": "Tag hdlproteins",
      "topics": [
        "tag_hdlproteins"
      ]
    },
    {
      "page": "TAXON_TO_ORGNAME",
      "title": "Annotation Maps",
      "topics": [
        "ABBREV_TO_ORGNAME",
        "EXISTENCE_TO_NUMBER",
        "REVIEWED_TO_NUMBER",
        "TAXON_TO_ORGNAME"
      ]
    },
    {
      "page": "TESTS",
      "title": "Statistical models supported in autonomics",
      "topics": [
        "TESTS"
      ]
    },
    {
      "page": "tpm",
      "title": "Get/Set tpm",
      "topics": [
        "tpm",
        "tpm,SummarizedExperiment-method",
        "tpm<-",
        "tpm<-,SummarizedExperiment,matrix-method",
        "tpm<-,SummarizedExperiment,numeric-method"
      ]
    },
    {
      "page": "TRANSFORMENGINES",
      "title": "Data Transformation Methods",
      "topics": [
        "TRANSFORMENGINES",
        "TRANSFORMSTRICT"
      ]
    },
    {
      "page": "twofactor_sumexp",
      "title": "twofactor sumexp",
      "topics": [
        "twofactor_sumexp"
      ]
    },
    {
      "page": "uncollapse",
      "title": "Uncollapse/Recollapse",
      "topics": [
        "recollapse",
        "uncollapse"
      ]
    },
    {
      "page": "values",
      "title": "Get/Set expr values",
      "topics": [
        "values",
        "values,SummarizedExperiment-method",
        "values<-",
        "values<-,SummarizedExperiment,matrix-method",
        "values<-,SummarizedExperiment,numeric-method"
      ]
    },
    {
      "page": "varlevels_dont_clash",
      "title": "Are varlevels unique",
      "topics": [
        "varlevels_dont_clash",
        "varlevels_dont_clash.data.table",
        "varlevels_dont_clash.SummarizedExperiment"
      ]
    },
    {
      "page": "venn_detects",
      "title": "Venn detects",
      "topics": [
        "venn_detects"
      ]
    },
    {
      "page": "weights",
      "title": "Get/Set weights",
      "topics": [
        "weights",
        "weights,SummarizedExperiment-method",
        "weights<-",
        "weights<-,SummarizedExperiment,matrix-method",
        "weights<-,SummarizedExperiment,NULL-method",
        "weights<-,SummarizedExperiment,numeric-method"
      ]
    },
    {
      "page": "write_xl",
      "title": "Write xl",
      "topics": [
        "write_ods",
        "write_xl"
      ]
    },
    {
      "page": "X",
      "title": "Model based prediction",
      "topics": [
        "beta",
        "X"
      ]
    },
    {
      "page": "zero_to_na",
      "title": "Change nondetect representation",
      "topics": [
        "inf_to_na",
        "minusinf_to_na",
        "nan_to_na",
        "na_to_string",
        "na_to_zero",
        "zero_to_na"
      ]
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  "_vignettes": [
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      "source": "autonomics_platformaware_analysis.Rmd",
      "filename": "autonomics_platformaware_analysis.html",
      "title": "autonomics: platform-aware analysis",
      "engine": "knitr::rmarkdown",
      "headings": [
        "Abstract",
        "RNAseq",
        "read_rnaseq_counts",
        "read_rnaseq_bams",
        "cpm/tmm/voom effects on power",
        "Proteingroups/phosphosites",
        "LFQ intensities",
        "Normalized ratios",
        "Metabolon",
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      ],
      "created": "2023-12-15 13:08:43",
      "modified": "2024-11-04 12:53:01",
      "commits": 10
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  "_indexed": true,
  "_nocasepkg": "autonomics",
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