{
  "_id": "6a1861e6acfb0bcc41dbe74a",
  "Package": "artMS",
  "Type": "Package",
  "Title": "Analytical R tools for Mass Spectrometry",
  "Version": "1.31.0",
  "Date": "2021-07-13",
  "Authors@R": "c(person(\"David\", \"Jimenez-Morales\", role = c(\"aut\",\"cre\"),\nemail = \"biodavidjm@gmail.com\",\ncomment = c(ORCID = \"0000-0003-4356-6461\")),\nperson(\"Alexandre\", \"Rosa Campos\", role = c(\"aut\",\"ctb\"),\ncomment = c(ORCID = \"0000-0003-3988-7764\")),\nperson(\"John\", \"Von Dollen\", role = c(\"aut\")),\nperson(\"Nevan\", \"Krogan\", role = c(\"aut\"),\ncomment = c(ORCID = \"0000-0003-4902-337X\")),\nperson(\"Danielle\", \"Swaney\", role = c(\"aut\", \"ctb\"),\ncomment = c(ORCID = \"0000-0001-6119-6084\")))",
  "Description": "artMS provides a set of tools for the analysis of\nproteomics label-free datasets. It takes as input the MaxQuant\nsearch result output (evidence.txt file) and performs quality\ncontrol, relative quantification using MSstats, downstream\nanalysis and integration. artMS also provides a set of\nfunctions to re-format and make it compatible with other\nanalytical tools, including, SAINTq, SAINTexpress, Phosfate,\nand PHOTON. Check [http://artms.org](http://artms.org) for\ndetails.",
  "License": "GPL (>= 3) + file LICENSE",
  "URL": "http://artms.org",
  "BugReports": "https://github.com/biodavidjm/artMS/issues",
  "Encoding": "UTF-8",
  "LazyLoad": "yes",
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  "biocViews": "Proteomics, DifferentialExpression, BiomedicalInformatics,\nSystemsBiology, MassSpectrometry, Annotation, QualityControl,\nGeneSetEnrichment, Clustering, Normalization, ImmunoOncology,\nMultipleComparison",
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  "Repository": "https://bioc.r-universe.dev",
  "Date/Publication": "2026-04-28 12:49:06 UTC",
  "RemoteUrl": "https://github.com/bioc/artMS",
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  "Packaged": {
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  "Author": "David Jimenez-Morales [aut, cre] (ORCID:\n<https://orcid.org/0000-0003-4356-6461>),\nAlexandre Rosa Campos [aut, ctb] (ORCID:\n<https://orcid.org/0000-0003-3988-7764>),\nJohn Von Dollen [aut],\nNevan Krogan [aut] (ORCID: <https://orcid.org/0000-0003-4902-337X>),\nDanielle Swaney [aut, ctb] (ORCID:\n<https://orcid.org/0000-0001-6119-6084>)",
  "Maintainer": "David Jimenez-Morales <biodavidjm@gmail.com>",
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  "_assets": [
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    "extra/citation.cff",
    "extra/citation.html",
    "extra/citation.json",
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    "extra/contents.json",
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  "_homeurl": "https://github.com/biodavidjm/artms",
  "_realowner": "bioc",
  "_cranurl": false,
  "_exports": [
    "artmsAnalysisQuantifications",
    "artmsAnnotateSpecie",
    "artmsAnnotationUniprot",
    "artmsAvgIntensityRT",
    "artmsChangeColumnName",
    "artmsConvertMetabolomics",
    "artmsDataPlots",
    "artmsEnrichLog2fc",
    "artmsEnrichProfiler",
    "artmsEvidenceToSaintExpress",
    "artmsEvidenceToSAINTq",
    "artmsFilterEvidenceContaminants",
    "artmsGeneratePhSiteExtended",
    "artmsIsEvidenceNewVersion",
    "artmsIsSpeciesSupported",
    "artmsLeaveOnlyUniprotEntryID",
    "artmsMapUniprot2Entrez",
    "artmsMergeEvidenceAndKeys",
    "artmsMsstatsSummary",
    "artmsPhosfateOutput",
    "artmsPhotonOutput",
    "artmsPlotHeatmapQuant",
    "artmsProtein2SiteConversion",
    "artmsQualityControlEvidenceBasic",
    "artmsQualityControlEvidenceExtended",
    "artmsQualityControlMetabolomics",
    "artmsQualityControlSummaryExtended",
    "artmsQuantification",
    "artmsResultsWide",
    "artmsSILACtoLong",
    "artmsSpectralCounts",
    "artmsVolcanoPlot",
    "artmsWriteConfigYamlFile"
  ],
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      "name": "artms_config",
      "title": "artMS configuration template",
      "object": "artms_config",
      "class": [
        "list"
      ],
      "fields": [],
      "table": false,
      "tojson": true
    },
    {
      "name": "artms_data_corum_mito_database",
      "title": "CORUM Protein Complexes database use for complex enrichment analysis",
      "object": "artms_data_corum_mito_database",
      "class": [
        "data.frame"
      ],
      "fields": [
        "ComplexID",
        "ComplexName",
        "Organism",
        "Synonyms",
        "Cell.line",
        "subunits.UniProt.IDs.",
        "subunits.Entrez.IDs.",
        "Protein.complex.purification.method",
        "GO.ID",
        "GO.description",
        "FunCat.ID",
        "FunCat.description",
        "PubMed.ID",
        "subunits.Protein.name.",
        "subunits.Gene.name.",
        "subunits.Gene.name.syn.",
        "Disease.comment",
        "Subunits.comment",
        "Complex.comment",
        "SWISSPROT.organism"
      ],
      "rows": 3616,
      "table": true,
      "tojson": true
    },
    {
      "name": "artms_data_pathogen_LPN",
      "title": "LPN PATHOGEN: Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513) UNIPROT IDS",
      "object": "artms_data_pathogen_LPN",
      "class": [
        "data.frame"
      ],
      "fields": [
        "Entry"
      ],
      "rows": 2930,
      "table": true,
      "tojson": true
    },
    {
      "name": "artms_data_pathogen_TB",
      "title": "TB PATHOGEN: Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman) UNIPROTS IDS",
      "object": "artms_data_pathogen_TB",
      "class": [
        "data.frame"
      ],
      "fields": [
        "Entry"
      ],
      "rows": 4222,
      "table": true,
      "tojson": true
    },
    {
      "name": "artms_data_ph_config",
      "title": "artMS configuration for the available PH dataset",
      "object": "artms_data_ph_config",
      "class": [
        "list"
      ],
      "fields": [],
      "table": false,
      "tojson": true
    },
    {
      "name": "artms_data_ph_contrast",
      "title": "Contrast example for the PH dataset",
      "object": "artms_data_ph_contrast",
      "class": [
        "character"
      ],
      "fields": [],
      "table": false,
      "tojson": true
    },
    {
      "name": "artms_data_ph_evidence",
      "title": "Evidence file example",
      "object": "artms_data_ph_evidence",
      "class": [
        "data.frame"
      ],
      "fields": [
        "Sequence",
        "Length",
        "Modifications",
        "Modified.sequence",
        "Oxidation..M..Probabilities",
        "Phospho..STY..Probabilities",
        "Oxidation..M..Score.Diffs",
        "Phospho..STY..Score.Diffs",
        "Oxidation..M.",
        "Phospho..STY.",
        "Missed.cleavages",
        "Proteins",
        "Leading.proteins",
        "Leading.razor.protein",
        "Type",
        "Raw.file",
        "MS.MS.m.z",
        "Charge",
        "m.z",
        "Mass",
        "Resolution",
        "Mass.error..ppm.",
        "Mass.error..Da.",
        "Uncalibrated.mass.error..ppm.",
        "Uncalibrated.mass.error..Da.",
        "Calibrated.retention.time",
        "Retention.time",
        "Retention.length",
        "PEP",
        "MS.MS.count",
        "MS.MS.scan.number",
        "Score",
        "Delta.score",
        "Intensity",
        "Reverse",
        "Potential.contaminant"
      ],
      "rows": 5004,
      "table": true,
      "tojson": true
    },
    {
      "name": "artms_data_ph_keys",
      "title": "Keys File Example",
      "object": "artms_data_ph_keys",
      "class": [
        "data.frame"
      ],
      "fields": [
        "RawFile",
        "IsotopeLabelType",
        "Condition",
        "BioReplicate",
        "Run"
      ],
      "rows": 4,
      "table": true,
      "tojson": true
    },
    {
      "name": "artms_data_ph_msstats_modelqc",
      "title": "MSstats modelQC example",
      "object": "artms_data_ph_msstats_modelqc",
      "class": [
        "data.frame"
      ],
      "fields": [
        "RUN",
        "Protein",
        "ABUNDANCE",
        "originalRUN",
        "GROUP",
        "SUBJECT",
        "TotalGroupMeasurements",
        "NumMeasuredFeature",
        "MissingPercentage",
        "more50missing",
        "NumImputedFeature",
        "residuals",
        "fitted"
      ],
      "rows": 24162,
      "table": true,
      "tojson": true
    },
    {
      "name": "artms_data_ph_msstats_results",
      "title": "MSstats results example",
      "object": "artms_data_ph_msstats_results",
      "class": [
        "data.frame"
      ],
      "fields": [
        "Protein",
        "Label",
        "log2FC",
        "SE",
        "Tvalue",
        "DF",
        "pvalue",
        "adj.pvalue",
        "issue",
        "MissingPercentage",
        "ImputationPercentage"
      ],
      "rows": 3413,
      "table": true,
      "tojson": true
    },
    {
      "name": "artms_data_randomDF",
      "title": "Random data set",
      "object": "artms_data_randomDF",
      "class": [
        "data.frame"
      ],
      "fields": [
        "X1",
        "X2",
        "X3",
        "X4",
        "X5",
        "X6",
        "X7",
        "X8",
        "X9",
        "X10"
      ],
      "rows": 100,
      "table": true,
      "tojson": true
    }
  ],
  "_help": [
    {
      "page": "artms_config",
      "title": "artMS configuration template",
      "topics": [
        "artms_config"
      ]
    },
    {
      "page": "artms_data_corum_mito_database",
      "title": "CORUM Protein Complexes database use for complex enrichment analysis",
      "topics": [
        "artms_data_corum_mito_database"
      ]
    },
    {
      "page": "artms_data_pathogen_LPN",
      "title": "LPN PATHOGEN: Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513) UNIPROT IDS",
      "topics": [
        "artms_data_pathogen_LPN"
      ]
    },
    {
      "page": "artms_data_pathogen_TB",
      "title": "TB PATHOGEN: Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman) UNIPROTS IDS",
      "topics": [
        "artms_data_pathogen_TB"
      ]
    },
    {
      "page": "artms_data_ph_config",
      "title": "artMS configuration for the available PH dataset",
      "topics": [
        "artms_data_ph_config"
      ]
    },
    {
      "page": "artms_data_ph_contrast",
      "title": "Contrast example for the PH dataset",
      "topics": [
        "artms_data_ph_contrast"
      ]
    },
    {
      "page": "artms_data_ph_evidence",
      "title": "Evidence file example",
      "topics": [
        "artms_data_ph_evidence"
      ]
    },
    {
      "page": "artms_data_ph_keys",
      "title": "Keys File Example",
      "topics": [
        "artms_data_ph_keys"
      ]
    },
    {
      "page": "artms_data_ph_msstats_modelqc",
      "title": "MSstats modelQC example",
      "topics": [
        "artms_data_ph_msstats_modelqc"
      ]
    },
    {
      "page": "artms_data_ph_msstats_results",
      "title": "MSstats results example",
      "topics": [
        "artms_data_ph_msstats_results"
      ]
    },
    {
      "page": "artms_data_randomDF",
      "title": "Random data set",
      "topics": [
        "artms_data_randomDF"
      ]
    },
    {
      "page": "artmsAnalysisQuantifications",
      "title": "Analysis of the Relative Quantifications",
      "topics": [
        "artmsAnalysisQuantifications"
      ]
    },
    {
      "page": "artmsAnnotateSpecie",
      "title": "Adding a column with the species name",
      "topics": [
        "artmsAnnotateSpecie"
      ]
    },
    {
      "page": "artmsAnnotationUniprot",
      "title": "Annotate table with Gene Symbol and Name based on Uniprot ID(s)",
      "topics": [
        "artmsAnnotationUniprot"
      ]
    },
    {
      "page": "artmsAvgIntensityRT",
      "title": "Summarize average intensity and retention time per protein",
      "topics": [
        "artmsAvgIntensityRT"
      ]
    },
    {
      "page": "artmsChangeColumnName",
      "title": "Change a specific column name in a given data.frame",
      "topics": [
        "artmsChangeColumnName"
      ]
    },
    {
      "page": "artmsConvertMetabolomics",
      "title": "Convert Markview Metabolomics file (alignment table) into a artMS compatible format",
      "topics": [
        "artmsConvertMetabolomics"
      ]
    },
    {
      "page": "artmsDataPlots",
      "title": "Individual Normalized abundance dot plots for every protein",
      "topics": [
        "artmsDataPlots"
      ]
    },
    {
      "page": "artmsEnrichLog2fc",
      "title": "Enrichment of changes in protein abundance or PTMs",
      "topics": [
        "artmsEnrichLog2fc"
      ]
    },
    {
      "page": "artmsEnrichProfiler",
      "title": "Enrichment analysis using GprofileR",
      "topics": [
        "artmsEnrichProfiler"
      ]
    },
    {
      "page": "artmsEvidenceToSaintExpress",
      "title": "MaxQuant evidence file to SAINTexpress format",
      "topics": [
        "artmsEvidenceToSaintExpress"
      ]
    },
    {
      "page": "artmsEvidenceToSAINTq",
      "title": "MaxQuant evidence file to SAINTq format",
      "topics": [
        "artmsEvidenceToSAINTq"
      ]
    },
    {
      "page": "artmsFilterEvidenceContaminants",
      "title": "Remove contaminants and empty proteins from the MaxQuant evidence file",
      "topics": [
        "artmsFilterEvidenceContaminants"
      ]
    },
    {
      "page": "artmsGeneratePhSiteExtended",
      "title": "Generate ph-site specific detailed file",
      "topics": [
        "artmsGeneratePhSiteExtended"
      ]
    },
    {
      "page": "artmsIsEvidenceNewVersion",
      "title": "Check if a given evidencee file was generated by a new version of MaxQuant (v>1)",
      "topics": [
        "artmsIsEvidenceNewVersion"
      ]
    },
    {
      "page": "artmsIsSpeciesSupported",
      "title": "Check if a species is supported and available",
      "topics": [
        "artmsIsSpeciesSupported"
      ]
    },
    {
      "page": "artmsLeaveOnlyUniprotEntryID",
      "title": "Leave only the Entry ID from a typical full Uniprot IDs in a given column",
      "topics": [
        "artmsLeaveOnlyUniprotEntryID"
      ]
    },
    {
      "page": "artmsMapUniprot2Entrez",
      "title": "Map GENE SYMBOL, NAME, AND ENTREZID to a vector of Uniprot IDS",
      "topics": [
        "artmsMapUniprot2Entrez"
      ]
    },
    {
      "page": "artmsMergeEvidenceAndKeys",
      "title": "Merge evidence.txt (or summary.txt) with keys.txt files",
      "topics": [
        "artmsMergeEvidenceAndKeys"
      ]
    },
    {
      "page": "artmsMsstatsSummary",
      "title": "Summarize the MSStats results and data quantification",
      "topics": [
        "artmsMsstatsSummary"
      ]
    },
    {
      "page": "artmsPhosfateOutput",
      "title": "Generate Phosfate Input file",
      "topics": [
        "artmsPhosfateOutput"
      ]
    },
    {
      "page": "artmsPhotonOutput",
      "title": "Generate PHOTON Input file",
      "topics": [
        "artmsPhotonOutput"
      ]
    },
    {
      "page": "artmsPlotHeatmapQuant",
      "title": "Outputs a heatmap of the MSStats results created using the log2fold changes",
      "topics": [
        "artmsPlotHeatmapQuant"
      ]
    },
    {
      "page": "artmsProtein2SiteConversion",
      "title": "Converts the Protein ID column of the evidence file selected by the user to mod-site-specific notation: 'ProteinID' to 'ProteinID_AAnumber' notation",
      "topics": [
        "artmsProtein2SiteConversion"
      ]
    },
    {
      "page": "artmsQualityControlEvidenceBasic",
      "title": "Quality Control analysis of the MaxQuant evidence file",
      "topics": [
        "artmsQualityControlEvidenceBasic"
      ]
    },
    {
      "page": "artmsQualityControlEvidenceExtended",
      "title": "Extended Quality Control of the MaxQuant evidence.txt file",
      "topics": [
        "artmsQualityControlEvidenceExtended"
      ]
    },
    {
      "page": "artmsQualityControlMetabolomics",
      "title": "Quality Control analysis of the evidence-like metabolomics dataset",
      "topics": [
        "artmsQualityControlMetabolomics"
      ]
    },
    {
      "page": "artmsQualityControlSummaryExtended",
      "title": "Quality Control of the MaxQuant summary.txt file",
      "topics": [
        "artmsQualityControlSummaryExtended"
      ]
    },
    {
      "page": "artmsQuantification",
      "title": "Relative quantification using MSstats",
      "topics": [
        "artmsQuantification"
      ]
    },
    {
      "page": "artmsResultsWide",
      "title": "Reshape the MSstats results file from long to wide format",
      "topics": [
        "artmsResultsWide"
      ]
    },
    {
      "page": "artmsSILACtoLong",
      "title": "Convert the SILAC evidence file to MSstats format",
      "topics": [
        "artmsSILACtoLong"
      ]
    },
    {
      "page": "artmsSpectralCounts",
      "title": "Outputs the spectral counts from the MaxQuant evidence file.",
      "topics": [
        "artmsSpectralCounts"
      ]
    },
    {
      "page": "artmsVolcanoPlot",
      "title": "Volcano plot (log2fc / pvalues)",
      "topics": [
        "artmsVolcanoPlot"
      ]
    },
    {
      "page": "artmsWriteConfigYamlFile",
      "title": "Write out a template file of the artMS configuration file (yaml)",
      "topics": [
        "artmsWriteConfigYamlFile"
      ]
    }
  ],
  "_readme": "https://github.com/bioc/artMS/raw/HEAD/README.md",
  "_rundeps": [
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    "bit64",
    "bitops",
    "blob",
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    "bslib",
    "cachem",
    "caTools",
    "checkmate",
    "circlize",
    "cli",
    "cluster",
    "colorspace",
    "corrplot",
    "cpp11",
    "crayon",
    "crosstalk",
    "curl",
    "data.table",
    "DBI",
    "digest",
    "dplyr",
    "evaluate",
    "farver",
    "fastmap",
    "fontawesome",
    "formatR",
    "fs",
    "futile.logger",
    "futile.options",
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    "ggdendro",
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    "ggrepel",
    "GlobalOptions",
    "glue",
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    "gtools",
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    "htmltools",
    "htmlwidgets",
    "httr",
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    "KEGGREST",
    "KernSmooth",
    "knitr",
    "labeling",
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    "lattice",
    "lazyeval",
    "lifecycle",
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    "lme4",
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    "magrittr",
    "marray",
    "MASS",
    "Matrix",
    "memoise",
    "mime",
    "minqa",
    "MSstats",
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    "nlme",
    "nloptr",
    "openssl",
    "openxlsx",
    "org.Hs.eg.db",
    "otel",
    "pheatmap",
    "pillar",
    "pixmap",
    "pkgconfig",
    "plotly",
    "plyr",
    "png",
    "preprocessCore",
    "promises",
    "purrr",
    "R6",
    "rappdirs",
    "rbibutils",
    "RColorBrewer",
    "Rcpp",
    "RcppArmadillo",
    "RcppEigen",
    "Rdpack",
    "reformulas",
    "rlang",
    "rmarkdown",
    "RSQLite",
    "S4Vectors",
    "S7",
    "sass",
    "scales",
    "segmented",
    "Seqinfo",
    "seqinr",
    "shape",
    "sp",
    "statmod",
    "stringi",
    "stringr",
    "survival",
    "sys",
    "tibble",
    "tidyr",
    "tidyselect",
    "tinytex",
    "UpSetR",
    "utf8",
    "vctrs",
    "VennDiagram",
    "viridisLite",
    "withr",
    "xfun",
    "XVector",
    "yaml",
    "zip"
  ],
  "_vignettes": [
    {
      "source": "artMS_vignette.Rmd",
      "filename": "artMS_vignette.html",
      "title": "artMS: Analytical R Tools for Mass Spectrometry",
      "author": "David Jimenez-Morales",
      "engine": "knitr::rmarkdown",
      "headings": [
        "OVERVIEW",
        "What's new?",
        "How to install",
        "Bioconductor",
        "Development version from Github (unstable)",
        "Input files",
        "Configuration file",
        "Basic workflows",
        "Proteomics",
        "Metabolomics (unstable)",
        "REQUIRED INPUT FILES",
        "evidence.txt",
        "keys.txt",
        "contrast.txt",
        "The artMS configuration file",
        "Section: files",
        "Section: qc",
        "Section: data",
        "Section: msstats",
        "Section: output_extras",
        "Special case: Protein fractionation",
        "Special case: SILAC",
        "QUALITY CONTROL",
        "Basic QC (evidence.txt-based)",
        "Extended QC (evidence.txt-based)",
        "Extended QC (summary.txt based)",
        "RELATIVE QUANTIFICATION",
        "Quantification of Changes in Global Protein Abundance",
        "Quantification of Changes in Global Phosphorylation, Ubiquitination, Acetylation (or any PTM)",
        "PTM-Site/Peptide-specific Quantification of Changes (PH, UB, AC)",
        "Output files",
        "TXT (tab delimited) files",
        "Plots (pdf)",
        "ANALYSIS OF QUANTIFICATIONS",
        "Inputs",
        "Outputs",
        "MISCELLANEOUS FUNCTIONS",
        "Annotate data.frame with Gene Symbol, Name, ENTREZ based on Uniprot IDs",
        "Average Intensity, RT, CR",
        "Change column name",
        "Individual abundance dot plots",
        "Enrichment analysis function",
        "Enrichment analysis using gProfileR",
        "MaxQuant evidence file to SAINTexpress format",
        "MaxQuant evidence file to SAINTq format",
        "Generate Phosfate input file",
        "Generate Photon input file",
        "Remove contaminants and empty proteins from the MaxQuant evidence file",
        "Generate ph-site specific evidence file",
        "METABOLOMICS",
        "Convert Metabolomics",
        "QC Metabolomics",
        "Relative Quantification:",
        "TESTING FILES",
        "HELP"
      ],
      "created": "2018-06-13 01:08:40",
      "modified": "2021-07-14 06:53:05",
      "commits": 59
    }
  ],
  "_score": 6.702430536445525,
  "_indexed": true,
  "_nocasepkg": "artms",
  "_universes": [
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    "biodavidjm"
  ],
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