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  "Package": "TFHAZ",
  "Type": "Package",
  "Title": "Transcription Factor High Accumulation Zones",
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  "Author": "Alberto Marchesi, Silvia Cascianelli, Marco Masseroli",
  "Maintainer": "Gaia Ceddia <gaia.ceddia@polimi.it>",
  "Description": "It finds trascription factor (TF) high accumulation DNA\nzones, i.e., regions along the genome where there is a high\npresence of different transcription factors. Starting from a\ndataset containing the genomic positions of TF binding regions,\nfor each base of the selected chromosome the accumulation of\nTFs is computed. Three different types of accumulation (TF,\nregion and base accumulation) are available, together with the\npossibility of considering, in the single base accumulation\ncomputing, the TFs present not only in that single base, but\nalso in its neighborhood, within a window of a given width. Two\ndifferent methods for the search of TF high accumulation DNA\nzones, called \"binding regions\" and \"overlaps\", are available.\nIn addition, some functions are provided in order to analyze,\nvisualize and compare results obtained with different input\nparameters.",
  "License": "Artistic-2.0",
  "Encoding": "UTF-8",
  "biocViews": "Software, BiologicalQuestion, Transcription, ChIPSeq,\nCoverage",
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  "Repository": "https://bioc.r-universe.dev",
  "Date/Publication": "2026-04-28 12:46:22 UTC",
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      "title": "Creates a vector with accumulation counts of transcription factors for each chromosome base.",
      "topics": [
        "accumulation"
      ]
    },
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    },
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      "title": "Plots the accumulation vector obtained with the accumulation function.",
      "topics": [
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    },
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      "topics": [
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      "filename": "TFHAZ.html",
      "title": "TFHAZ",
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      "engine": "knitr::rmarkdown",
      "headings": [
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        "Transcription factor accumulation",
        "Transcription factor dense DNA zones",
        "Transcription factor dense DNA zones analysis",
        "Transcription factor high accumulation DNA zones",
        "Acknowledgement",
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